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- W2133319415 abstract "BY THE USE OF radioiodine it has been shown that circulating iodide rapidly appears in the thyroid gland as organic compounds that can be separated into diiodotyrosine′like and thyroxine′like fractions (1, 2). A larger portion of the gland's radioiodine was always present as diiodotyrosine than as thyroxine. In the plasma these labeled organic iodine compounds were present as early as two hours after the introduction of radioiodine. At this early interval the level of organicallybound radioiodine was low in plasma, and the diiodotyrosine fraction predominates. At later intervals the amount of organically′bound radioiodine increased, and the thyroxine′like fraction in the plasma then far exceeded the diiodotyrosine′like fraction, even though the major fraction of the gland's labeled iodine was still present as diiodotyrosine. The gland made hyperactive by the injection of thyrotropic hormone was characterized by a greater uptake of circulating radioiodine than the normal gland(2)." @default.
- W2133319415 created "2016-06-24" @default.
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- W2133319415 date "1942-03-01" @default.
- W2133319415 modified "2023-09-27" @default.
- W2133319415 title "RADIOACTIVE IODINE AS AN INDICATOR OF THE METABOLISM OF IODINE IV. THE DISTRIBUTION OF LABELED THYROXINE AND DIIODOTYROSINE IN LIVER, MUSCLE AND SMALL INTESTINE1" @default.
- W2133319415 doi "https://doi.org/10.1210/endo-30-3-487" @default.
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