Matches in SemOpenAlex for { <https://semopenalex.org/work/W2133336368> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2133336368 endingPage "419" @default.
- W2133336368 startingPage "415" @default.
- W2133336368 abstract "Rats and mice have been used to evaluate effects of natural and synthetic oestrogens. However, data about oestrogen's effects on haemostasis in rodents is very limited. The aim of this work was to standardize blood coagulation screening tests in adult male, female, and ovariectomized (Ovx) Wistar rats and CD1 mice in an effort to evaluate the influence of gender and species differences on haemostasis.Values were obtained for the following haemostatic parameters: prothrombin time (PT), activated partial thromboplastin time (aPTT), thrombin clotting time (TT), and fibrinogen (FIB), through modifications of the conventional techniques used for human blood coagulation analysis.Both rats and mice showed gender intra-species and inter-species differences of high significance in PT, aPTT, TT, and FIB values. Intra-species differences were found in TT (+10% p<0.01) and FIB concentration (-21% p<0.001) between male and Ovx rats. Male vs. Ovx mice showed a TT difference of -20% (p<0.001). The main inter-species differences found were PT values of male rats vs. male mice (-39%) and female rats vs. female mice (-35%, both p<0.001). Female rats and mice aPTT values vs. those corresponding to Ovx animals showed differences of +15% and +32% (p<0.001), respectively.These data reveal the great importance of gender intra- and inter-species differences on the values of haemostatic screening tests, which should be taken into consideration when evaluating the effects of oestrogens and other drugs on the coagulation system." @default.
- W2133336368 created "2016-06-24" @default.
- W2133336368 creator A5013664664 @default.
- W2133336368 creator A5036690099 @default.
- W2133336368 creator A5082570591 @default.
- W2133336368 date "2007-01-01" @default.
- W2133336368 modified "2023-10-03" @default.
- W2133336368 title "Gender and inter-species influence on coagulation tests of rats and mice" @default.
- W2133336368 cites W138463622 @default.
- W2133336368 cites W1841210688 @default.
- W2133336368 cites W1978039741 @default.
- W2133336368 cites W1991152004 @default.
- W2133336368 cites W1996199972 @default.
- W2133336368 cites W2003660935 @default.
- W2133336368 cites W2036705142 @default.
- W2133336368 cites W2039945612 @default.
- W2133336368 cites W2041349540 @default.
- W2133336368 cites W2045951087 @default.
- W2133336368 cites W2050638589 @default.
- W2133336368 cites W2067306065 @default.
- W2133336368 cites W2084108616 @default.
- W2133336368 cites W2091246651 @default.
- W2133336368 cites W2118282690 @default.
- W2133336368 cites W2128191051 @default.
- W2133336368 cites W2333330110 @default.
- W2133336368 cites W2405052465 @default.
- W2133336368 cites W4230354809 @default.
- W2133336368 cites W4252093373 @default.
- W2133336368 doi "https://doi.org/10.1016/j.thromres.2006.10.012" @default.
- W2133336368 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17156826" @default.
- W2133336368 hasPublicationYear "2007" @default.
- W2133336368 type Work @default.
- W2133336368 sameAs 2133336368 @default.
- W2133336368 citedByCount "39" @default.
- W2133336368 countsByYear W21333363682012 @default.
- W2133336368 countsByYear W21333363682013 @default.
- W2133336368 countsByYear W21333363682014 @default.
- W2133336368 countsByYear W21333363682015 @default.
- W2133336368 countsByYear W21333363682016 @default.
- W2133336368 countsByYear W21333363682017 @default.
- W2133336368 countsByYear W21333363682018 @default.
- W2133336368 countsByYear W21333363682019 @default.
- W2133336368 countsByYear W21333363682020 @default.
- W2133336368 countsByYear W21333363682022 @default.
- W2133336368 countsByYear W21333363682023 @default.
- W2133336368 crossrefType "journal-article" @default.
- W2133336368 hasAuthorship W2133336368A5013664664 @default.
- W2133336368 hasAuthorship W2133336368A5036690099 @default.
- W2133336368 hasAuthorship W2133336368A5082570591 @default.
- W2133336368 hasConcept C126322002 @default.
- W2133336368 hasConcept C134018914 @default.
- W2133336368 hasConcept C16124881 @default.
- W2133336368 hasConcept C2777164284 @default.
- W2133336368 hasConcept C2778261982 @default.
- W2133336368 hasConcept C2778382381 @default.
- W2133336368 hasConcept C2778589496 @default.
- W2133336368 hasConcept C2779036427 @default.
- W2133336368 hasConcept C2780077467 @default.
- W2133336368 hasConcept C2780434524 @default.
- W2133336368 hasConcept C71924100 @default.
- W2133336368 hasConcept C77171857 @default.
- W2133336368 hasConcept C8264082 @default.
- W2133336368 hasConceptScore W2133336368C126322002 @default.
- W2133336368 hasConceptScore W2133336368C134018914 @default.
- W2133336368 hasConceptScore W2133336368C16124881 @default.
- W2133336368 hasConceptScore W2133336368C2777164284 @default.
- W2133336368 hasConceptScore W2133336368C2778261982 @default.
- W2133336368 hasConceptScore W2133336368C2778382381 @default.
- W2133336368 hasConceptScore W2133336368C2778589496 @default.
- W2133336368 hasConceptScore W2133336368C2779036427 @default.
- W2133336368 hasConceptScore W2133336368C2780077467 @default.
- W2133336368 hasConceptScore W2133336368C2780434524 @default.
- W2133336368 hasConceptScore W2133336368C71924100 @default.
- W2133336368 hasConceptScore W2133336368C77171857 @default.
- W2133336368 hasConceptScore W2133336368C8264082 @default.
- W2133336368 hasIssue "3" @default.
- W2133336368 hasLocation W21333363681 @default.
- W2133336368 hasLocation W21333363682 @default.
- W2133336368 hasOpenAccess W2133336368 @default.
- W2133336368 hasPrimaryLocation W21333363681 @default.
- W2133336368 hasRelatedWork W1591132000 @default.
- W2133336368 hasRelatedWork W1975287477 @default.
- W2133336368 hasRelatedWork W2010203179 @default.
- W2133336368 hasRelatedWork W2357452117 @default.
- W2133336368 hasRelatedWork W2379432586 @default.
- W2133336368 hasRelatedWork W2389270980 @default.
- W2133336368 hasRelatedWork W2413023519 @default.
- W2133336368 hasRelatedWork W2921976368 @default.
- W2133336368 hasRelatedWork W3031692095 @default.
- W2133336368 hasRelatedWork W4285367771 @default.
- W2133336368 hasVolume "120" @default.
- W2133336368 isParatext "false" @default.
- W2133336368 isRetracted "false" @default.
- W2133336368 magId "2133336368" @default.
- W2133336368 workType "article" @default.