FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2133358158> ?p ?o ?g. }

• W2133358158 endingPage "1149" @default.
• W2133358158 startingPage "1143" @default.
• W2133358158 abstract "Statins are powerful lipid-lowering drugs that have been proved effective in the prevention of coronary artery disease, clearly reducing the risk of mortality and cardiovascular events. Whether hyperlipidemic patients undergoing coronary artery bypass grafting profit from the lipid-lowering beneficial effects of statins is as yet uncertain. We sought to determine whether preoperative statin therapy may have an effect on outcome among hyperlipidemic patients undergoing coronary artery bypass grafting.From January 2000 through March 2006, prospectively recorded clinical data from 3346 consecutive patients undergoing isolated first-time elective coronary artery bypass grafting were analyzed for major adverse cardiac events and all-cause in-hospital mortality. Of these, 167 patients had preoperative statin-untreated hyperlipidemia (group 1), 2592 had statin-treated hyperlipidemia (group 2), and 587 had statin-untreated normolipidemia (group 3).Risk-adjusted multivariate logistic regression analysis revealed statin-treated hyperlipidemia (odds ratio, 0.42; 95% confidence interval, 0.26-0.69; P = .0007) and statin-untreated normolipidemia (odds ratio, 0.42; confidence interval, 0.26-0.69; P = .0007) to be independently associated with reduced in-hospital major adverse cardiac events but not with in-hospital mortality. To further control for selection bias, a computed propensity score matching based on 14 major preoperative risk factors was performed. After propensity matching, conditional logistic regression analysis confirmed statin-treated hyperlipidemia and statin-untreated normolipidemia to be strongly related to reduced in-hospital major adverse cardiac events (odds ratio, 0.41; 95% confidence interval, 0.24-0.71 [P = .0013] and odds ratio, 0.23; 95% confidence interval, 0.11-0.48 [P = .0001]) but not with in-hospital mortality (odds ratio, 1.18; 95% confidence interval, 0.36-3.87 [P = .79] and odds ratio, 1.10; 95% confidence interval, 0.32-4.41 [P = .80]) after coronary artery bypass grafting surgery.Hyperlipidemic, but not normolipidemic, patients have an increased risk for in-hospital major adverse cardiac events and therefore clearly benefit from preoperative statin therapy before coronary artery bypass grafting surgery." @default.
• W2133358158 created "2016-06-24" @default.
• W2133358158 creator A5026578073 @default.
• W2133358158 creator A5027270899 @default.
• W2133358158 creator A5028433112 @default.
• W2133358158 creator A5035620570 @default.
• W2133358158 creator A5038095500 @default.
• W2133358158 creator A5051558412 @default.
• W2133358158 creator A5061950827 @default.
• W2133358158 creator A5078366960 @default.
• W2133358158 creator A5087456689 @default.
• W2133358158 creator A5090617573 @default.
• W2133358158 date "2007-11-01" @default.
• W2133358158 modified "2023-09-23" @default.
• W2133358158 title "Lipid-lowering effect of preoperative statin therapy on postoperative major adverse cardiac events after coronary artery bypass surgery" @default.
• W2133358158 cites W137344628 @default.
• W2133358158 cites W1969100490 @default.
• W2133358158 cites W1998067901 @default.
• W2133358158 cites W2018229264 @default.
• W2133358158 cites W2020686426 @default.
• W2133358158 cites W2030475349 @default.
• W2133358158 cites W2047193080 @default.
• W2133358158 cites W2086110771 @default.
• W2133358158 cites W2087519582 @default.
• W2133358158 cites W2089268045 @default.
• W2133358158 cites W2090639306 @default.
• W2133358158 cites W2100767226 @default.
• W2133358158 cites W2106084279 @default.
• W2133358158 cites W2106343349 @default.
• W2133358158 cites W2114532627 @default.
• W2133358158 cites W2123793954 @default.
• W2133358158 cites W2125639599 @default.
• W2133358158 cites W2128883750 @default.
• W2133358158 cites W2135014890 @default.
• W2133358158 cites W2144448307 @default.
• W2133358158 cites W2155598961 @default.
• W2133358158 cites W2165560542 @default.
• W2133358158 cites W2247997571 @default.
• W2133358158 cites W4213213858 @default.
• W2133358158 doi "https://doi.org/10.1016/j.jtcvs.2007.07.029" @default.
• W2133358158 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17976441" @default.
• W2133358158 hasPublicationYear "2007" @default.
• W2133358158 type Work @default.
• W2133358158 sameAs 2133358158 @default.
• W2133358158 citedByCount "53" @default.
• W2133358158 countsByYear W21333581582012 @default.
• W2133358158 countsByYear W21333581582013 @default.
• W2133358158 countsByYear W21333581582014 @default.
• W2133358158 countsByYear W21333581582015 @default.
• W2133358158 countsByYear W21333581582016 @default.
• W2133358158 countsByYear W21333581582017 @default.
• W2133358158 countsByYear W21333581582018 @default.
• W2133358158 countsByYear W21333581582019 @default.
• W2133358158 crossrefType "journal-article" @default.
• W2133358158 hasAuthorship W2133358158A5026578073 @default.
• W2133358158 hasAuthorship W2133358158A5027270899 @default.
• W2133358158 hasAuthorship W2133358158A5028433112 @default.
• W2133358158 hasAuthorship W2133358158A5035620570 @default.
• W2133358158 hasAuthorship W2133358158A5038095500 @default.
• W2133358158 hasAuthorship W2133358158A5051558412 @default.
• W2133358158 hasAuthorship W2133358158A5061950827 @default.
• W2133358158 hasAuthorship W2133358158A5078366960 @default.
• W2133358158 hasAuthorship W2133358158A5087456689 @default.
• W2133358158 hasAuthorship W2133358158A5090617573 @default.
• W2133358158 hasBestOaLocation W21333581581 @default.
• W2133358158 hasConcept C126322002 @default.
• W2133358158 hasConcept C134018914 @default.
• W2133358158 hasConcept C141071460 @default.
• W2133358158 hasConcept C156957248 @default.
• W2133358158 hasConcept C164705383 @default.
• W2133358158 hasConcept C17923572 @default.
• W2133358158 hasConcept C197934379 @default.
• W2133358158 hasConcept C2775901492 @default.
• W2133358158 hasConcept C2776820930 @default.
• W2133358158 hasConcept C2776839432 @default.
• W2133358158 hasConcept C2778213512 @default.
• W2133358158 hasConcept C2778789114 @default.
• W2133358158 hasConcept C2779091943 @default.
• W2133358158 hasConcept C44249647 @default.
• W2133358158 hasConcept C555293320 @default.
• W2133358158 hasConcept C71924100 @default.
• W2133358158 hasConceptScore W2133358158C126322002 @default.
• W2133358158 hasConceptScore W2133358158C134018914 @default.
• W2133358158 hasConceptScore W2133358158C141071460 @default.
• W2133358158 hasConceptScore W2133358158C156957248 @default.
• W2133358158 hasConceptScore W2133358158C164705383 @default.
• W2133358158 hasConceptScore W2133358158C17923572 @default.
• W2133358158 hasConceptScore W2133358158C197934379 @default.
• W2133358158 hasConceptScore W2133358158C2775901492 @default.
• W2133358158 hasConceptScore W2133358158C2776820930 @default.
• W2133358158 hasConceptScore W2133358158C2776839432 @default.
• W2133358158 hasConceptScore W2133358158C2778213512 @default.
• W2133358158 hasConceptScore W2133358158C2778789114 @default.
• W2133358158 hasConceptScore W2133358158C2779091943 @default.
• W2133358158 hasConceptScore W2133358158C44249647 @default.
• W2133358158 hasConceptScore W2133358158C555293320 @default.
• W2133358158 hasConceptScore W2133358158C71924100 @default.
• W2133358158 hasIssue "5" @default.

• next