FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2133516263> ?p ?o ?g. }

• W2133516263 endingPage "e81214" @default.
• W2133516263 startingPage "e81214" @default.
• W2133516263 abstract "Tick-borne encephalitis virus (TBEV) infects bank voles (Myodes glareolus) in nature, but the relevance of rodents for TBEV transmission and maintenance is unclear. We infected colonized bank voles subcutaneously to study and compare the infection kinetics, acute infection, and potential viral persistence of the three known TBEV subtypes: European (TBEV-Eur), Siberian (TBEV-Sib) and Far Eastern (TBEV-FE). All strains representing the three subtypes were infective and highly neurotropic. They induced (meningo)encephalitis in some of the animals, however most of the cases did not present with apparent clinical symptoms. TBEV-RNA was cleared significantly slower from the brain as compared to other organs studied. Supporting our earlier findings in natural rodent populations, TBEV-RNA could be detected in the brain for up to 168 days post infection, but we could not demonstrate infectivity by cell culture isolation. Throughout all time points post infection, RNA of the TBEV-FE was detected significantly more often than RNA of the other two strains in all organs studied. TBEV-FE also induced prolonged viremia, indicating distinctive kinetics in rodents in comparison to the other two subtypes. This study shows that bank voles can develop a neuroinvasive TBEV infection with persistence of viral RNA in brain, and mount an anti-TBEV IgG response. The findings also provide further evidence that bank voles can serve as sentinels for TBEV endemicity." @default.
• W2133516263 created "2016-06-24" @default.
• W2133516263 creator A5008115544 @default.
• W2133516263 creator A5009181517 @default.
• W2133516263 creator A5023869007 @default.
• W2133516263 creator A5024623241 @default.
• W2133516263 creator A5025873520 @default.
• W2133516263 creator A5028805230 @default.
• W2133516263 creator A5067119126 @default.
• W2133516263 date "2013-12-13" @default.
• W2133516263 modified "2023-10-16" @default.
• W2133516263 title "The Three Subtypes of Tick-Borne Encephalitis Virus Induce Encephalitis in a Natural Host, the Bank Vole (Myodes glareolus)" @default.
• W2133516263 cites W1964593874 @default.
• W2133516263 cites W1969861420 @default.
• W2133516263 cites W1979022596 @default.
• W2133516263 cites W1984143185 @default.
• W2133516263 cites W1986994060 @default.
• W2133516263 cites W1990432440 @default.
• W2133516263 cites W1993272811 @default.
• W2133516263 cites W1993620610 @default.
• W2133516263 cites W1996490949 @default.
• W2133516263 cites W2007510392 @default.
• W2133516263 cites W2009705112 @default.
• W2133516263 cites W2013208900 @default.
• W2133516263 cites W2013295291 @default.
• W2133516263 cites W2014192687 @default.
• W2133516263 cites W2015042599 @default.
• W2133516263 cites W2021485826 @default.
• W2133516263 cites W2022542855 @default.
• W2133516263 cites W2030684079 @default.
• W2133516263 cites W2035303426 @default.
• W2133516263 cites W2040690511 @default.
• W2133516263 cites W2056849822 @default.
• W2133516263 cites W2061804069 @default.
• W2133516263 cites W2062382041 @default.
• W2133516263 cites W2066164024 @default.
• W2133516263 cites W2070226770 @default.
• W2133516263 cites W2073366677 @default.
• W2133516263 cites W2074892837 @default.
• W2133516263 cites W2081069064 @default.
• W2133516263 cites W2082990183 @default.
• W2133516263 cites W2097563508 @default.
• W2133516263 cites W2128521636 @default.
• W2133516263 cites W2128694535 @default.
• W2133516263 cites W2135064888 @default.
• W2133516263 cites W2136533779 @default.
• W2133516263 cites W2139675730 @default.
• W2133516263 cites W2140025627 @default.
• W2133516263 cites W2141604566 @default.
• W2133516263 cites W2144578574 @default.
• W2133516263 cites W2152917543 @default.
• W2133516263 cites W2156473621 @default.
• W2133516263 cites W2159981210 @default.
• W2133516263 cites W2161330405 @default.
• W2133516263 cites W2166277388 @default.
• W2133516263 cites W2178397718 @default.
• W2133516263 cites W2259640758 @default.
• W2133516263 cites W2329239633 @default.
• W2133516263 cites W2597853440 @default.
• W2133516263 cites W4376849567 @default.
• W2133516263 doi "https://doi.org/10.1371/journal.pone.0081214" @default.
• W2133516263 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3862475" @default.
• W2133516263 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24349041" @default.
• W2133516263 hasPublicationYear "2013" @default.
• W2133516263 type Work @default.
• W2133516263 sameAs 2133516263 @default.
• W2133516263 citedByCount "48" @default.
• W2133516263 countsByYear W21335162632014 @default.
• W2133516263 countsByYear W21335162632015 @default.
• W2133516263 countsByYear W21335162632016 @default.
• W2133516263 countsByYear W21335162632017 @default.
• W2133516263 countsByYear W21335162632018 @default.
• W2133516263 countsByYear W21335162632019 @default.
• W2133516263 countsByYear W21335162632020 @default.
• W2133516263 countsByYear W21335162632021 @default.
• W2133516263 countsByYear W21335162632022 @default.
• W2133516263 countsByYear W21335162632023 @default.
• W2133516263 crossrefType "journal-article" @default.
• W2133516263 hasAuthorship W2133516263A5008115544 @default.
• W2133516263 hasAuthorship W2133516263A5009181517 @default.
• W2133516263 hasAuthorship W2133516263A5023869007 @default.
• W2133516263 hasAuthorship W2133516263A5024623241 @default.
• W2133516263 hasAuthorship W2133516263A5025873520 @default.
• W2133516263 hasAuthorship W2133516263A5028805230 @default.
• W2133516263 hasAuthorship W2133516263A5067119126 @default.
• W2133516263 hasBestOaLocation W21335162631 @default.
• W2133516263 hasConcept C106358424 @default.
• W2133516263 hasConcept C126831891 @default.
• W2133516263 hasConcept C127413603 @default.
• W2133516263 hasConcept C159047783 @default.
• W2133516263 hasConcept C187320778 @default.
• W2133516263 hasConcept C18903297 @default.
• W2133516263 hasConcept C2522874641 @default.
• W2133516263 hasConcept C2776185481 @default.
• W2133516263 hasConcept C2776281056 @default.
• W2133516263 hasConcept C2777262387 @default.
• W2133516263 hasConcept C2778914748 @default.
• W2133516263 hasConcept C2779404267 @default.

• next