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• W2133673890 endingPage "24" @default.
• W2133673890 startingPage "24" @default.
• W2133673890 abstract "The targeted inactivation of a single oncogene can induce dramatic tumor regression, suggesting that cancers are “oncogene addicted.” Tumor regression following oncogene inactivation has been thought to be a consequence of restoration of normal physiological programs that induce proliferative arrest, apoptosis, differentiation, and cellular senescence. However, recent observations illustrate that oncogene addiction is highly dependent upon the host immune cells. In particular, CD4⁺ helper T cells were shown to be essential to the mechanism by which MYC or BCR-ABL inactivation elicits “oncogene withdrawal.” Hence, immune mediators contribute in multiple ways to the pathogenesis, prevention, and treatment of cancer, including mechanisms of tumor initiation, progression, and surveillance, but also oncogene inactivation-mediated tumor regression. Data from both the bench and the bedside illustrates that the inactivation of a driver oncogene can induce activation of the immune system that appears to be essential for sustained tumor regression." @default.
• W2133673890 created "2016-06-24" @default.
• W2133673890 creator A5010630509 @default.
• W2133673890 creator A5028169162 @default.
• W2133673890 creator A5044556894 @default.
• W2133673890 creator A5059317683 @default.
• W2133673890 date "2014-01-01" @default.
• W2133673890 modified "2023-09-23" @default.
• W2133673890 title "Oncogene withdrawal engages the immune system to induce sustained cancer regression" @default.
• W2133673890 cites W1483388049 @default.
• W2133673890 cites W1508135631 @default.
• W2133673890 cites W1522653492 @default.
• W2133673890 cites W1532472884 @default.
• W2133673890 cites W1572020409 @default.
• W2133673890 cites W1573646548 @default.
• W2133673890 cites W1595856931 @default.
• W2133673890 cites W1600042637 @default.
• W2133673890 cites W1637209605 @default.
• W2133673890 cites W188996788 @default.
• W2133673890 cites W1924088703 @default.
• W2133673890 cites W1964154017 @default.
• W2133673890 cites W1964703707 @default.
• W2133673890 cites W1964838758 @default.
• W2133673890 cites W1968713285 @default.
• W2133673890 cites W1969648097 @default.
• W2133673890 cites W1970798331 @default.
• W2133673890 cites W1976617226 @default.
• W2133673890 cites W1978236936 @default.
• W2133673890 cites W1982393730 @default.
• W2133673890 cites W1984940554 @default.
• W2133673890 cites W1991365287 @default.
• W2133673890 cites W1991505853 @default.
• W2133673890 cites W1992141113 @default.
• W2133673890 cites W1996949194 @default.
• W2133673890 cites W1999936662 @default.
• W2133673890 cites W2000033481 @default.
• W2133673890 cites W2000712177 @default.
• W2133673890 cites W2001415306 @default.
• W2133673890 cites W2004678195 @default.
• W2133673890 cites W2009197694 @default.
• W2133673890 cites W2009590986 @default.
• W2133673890 cites W2010069724 @default.
• W2133673890 cites W2010109350 @default.
• W2133673890 cites W2011435623 @default.
• W2133673890 cites W2013090484 @default.
• W2133673890 cites W2014624348 @default.
• W2133673890 cites W2016396363 @default.
• W2133673890 cites W2016612145 @default.
• W2133673890 cites W2017289276 @default.
• W2133673890 cites W2018105469 @default.
• W2133673890 cites W2019109464 @default.
• W2133673890 cites W2022861507 @default.
• W2133673890 cites W2023556472 @default.
• W2133673890 cites W2024735083 @default.
• W2133673890 cites W2026042733 @default.
• W2133673890 cites W2026164481 @default.
• W2133673890 cites W2028543184 @default.
• W2133673890 cites W2030816211 @default.
• W2133673890 cites W2031659092 @default.
• W2133673890 cites W2031751531 @default.
• W2133673890 cites W2032220572 @default.
• W2133673890 cites W2035982119 @default.
• W2133673890 cites W2036748804 @default.
• W2133673890 cites W2038444562 @default.
• W2133673890 cites W2042382656 @default.
• W2133673890 cites W2044341880 @default.
• W2133673890 cites W2044835625 @default.
• W2133673890 cites W2044886076 @default.
• W2133673890 cites W2045345142 @default.
• W2133673890 cites W2046161326 @default.
• W2133673890 cites W2049298804 @default.
• W2133673890 cites W2052874737 @default.
• W2133673890 cites W2054657650 @default.
• W2133673890 cites W2055724502 @default.
• W2133673890 cites W2056354270 @default.
• W2133673890 cites W2059888416 @default.
• W2133673890 cites W2060425936 @default.
• W2133673890 cites W2063192133 @default.
• W2133673890 cites W206701898 @default.
• W2133673890 cites W2068277353 @default.
• W2133673890 cites W2068302554 @default.
• W2133673890 cites W2070970701 @default.
• W2133673890 cites W2071507111 @default.
• W2133673890 cites W2076335443 @default.
• W2133673890 cites W2076866768 @default.
• W2133673890 cites W2086517030 @default.
• W2133673890 cites W2092018061 @default.
• W2133673890 cites W2092908366 @default.
• W2133673890 cites W2101040581 @default.
• W2133673890 cites W2102557111 @default.
• W2133673890 cites W2103675014 @default.
• W2133673890 cites W2103894337 @default.
• W2133673890 cites W2111381709 @default.
• W2133673890 cites W2114553148 @default.
• W2133673890 cites W2115586700 @default.
• W2133673890 cites W2116376943 @default.
• W2133673890 cites W2116813877 @default.
• W2133673890 cites W2117692326 @default.

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