Matches in SemOpenAlex for { <https://semopenalex.org/work/W2133750897> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W2133750897 endingPage "1819" @default.
- W2133750897 startingPage "1819" @default.
- W2133750897 abstract "Thrombotic arterial occlusion is the major cause of acute cardiovascular syndromes such as stroke and myocardial infarction. Exposing the thrombus to microbubbles in the presence of ultrasound facilitates thrombus disruption, and is thus a potentially powerful therapeutic strategy for thromboembolic diseases. However, optimization of “sonothrombolysis” is constrained by a lack of understanding of underlying mechanisms for blood clot disruption in response to ultrasound-induced microbubble vibrations. We tested the hypothesis that inertial cavitation induces mechanical clot disruption by optically characterizing lipid microbubble interactions with thrombus + ultrasound using an ultra-high speed microscopy imaging system capable of imaging at MHz frame rates. A microscope/acoustic stage was used to hold an experimentally created thrombus and microbubbles, which were insonified (1 MHz) during synchronized high speed imaging. Large amplitude microbubble oscillations in response to an inertial cavitation regime caused thrombus deformation and pitting. These data implicate a direct mechanical effect of oscillating microbubbles on mediating clot disruption." @default.
- W2133750897 created "2016-06-24" @default.
- W2133750897 creator A5081571713 @default.
- W2133750897 date "2015-09-01" @default.
- W2133750897 modified "2023-09-25" @default.
- W2133750897 title "Insights into mechanisms of sonothrombolysis using high speed imaging" @default.
- W2133750897 doi "https://doi.org/10.1121/1.4933771" @default.
- W2133750897 hasPublicationYear "2015" @default.
- W2133750897 type Work @default.
- W2133750897 sameAs 2133750897 @default.
- W2133750897 citedByCount "0" @default.
- W2133750897 crossrefType "journal-article" @default.
- W2133750897 hasAuthorship W2133750897A5081571713 @default.
- W2133750897 hasConcept C121332964 @default.
- W2133750897 hasConcept C126838900 @default.
- W2133750897 hasConcept C136229726 @default.
- W2133750897 hasConcept C143753070 @default.
- W2133750897 hasConcept C164705383 @default.
- W2133750897 hasConcept C192562407 @default.
- W2133750897 hasConcept C207057113 @default.
- W2133750897 hasConcept C24890656 @default.
- W2133750897 hasConcept C2781362458 @default.
- W2133750897 hasConcept C2985948822 @default.
- W2133750897 hasConcept C2986892559 @default.
- W2133750897 hasConcept C64012434 @default.
- W2133750897 hasConcept C71924100 @default.
- W2133750897 hasConceptScore W2133750897C121332964 @default.
- W2133750897 hasConceptScore W2133750897C126838900 @default.
- W2133750897 hasConceptScore W2133750897C136229726 @default.
- W2133750897 hasConceptScore W2133750897C143753070 @default.
- W2133750897 hasConceptScore W2133750897C164705383 @default.
- W2133750897 hasConceptScore W2133750897C192562407 @default.
- W2133750897 hasConceptScore W2133750897C207057113 @default.
- W2133750897 hasConceptScore W2133750897C24890656 @default.
- W2133750897 hasConceptScore W2133750897C2781362458 @default.
- W2133750897 hasConceptScore W2133750897C2985948822 @default.
- W2133750897 hasConceptScore W2133750897C2986892559 @default.
- W2133750897 hasConceptScore W2133750897C64012434 @default.
- W2133750897 hasConceptScore W2133750897C71924100 @default.
- W2133750897 hasIssue "3_Supplement" @default.
- W2133750897 hasLocation W21337508971 @default.
- W2133750897 hasOpenAccess W2133750897 @default.
- W2133750897 hasPrimaryLocation W21337508971 @default.
- W2133750897 hasRelatedWork W2045824469 @default.
- W2133750897 hasRelatedWork W2074882522 @default.
- W2133750897 hasRelatedWork W2098950482 @default.
- W2133750897 hasRelatedWork W2127480193 @default.
- W2133750897 hasRelatedWork W2131023610 @default.
- W2133750897 hasRelatedWork W2543550102 @default.
- W2133750897 hasRelatedWork W2622334269 @default.
- W2133750897 hasRelatedWork W2907222515 @default.
- W2133750897 hasRelatedWork W2965455797 @default.
- W2133750897 hasRelatedWork W4382199085 @default.
- W2133750897 hasVolume "138" @default.
- W2133750897 isParatext "false" @default.
- W2133750897 isRetracted "false" @default.
- W2133750897 magId "2133750897" @default.
- W2133750897 workType "article" @default.