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• W2133792826 endingPage "711" @default.
• W2133792826 startingPage "703" @default.
• W2133792826 abstract "Adipose tissue is an endocrine organ secreting biologically active factors called adipokines that act on both local and distant tissues. Adipokines have an important role in the development of obesity-related comorbidities not only in adults but also in children and adolescents. Retinol binding protein 4 (RBP4) is a recently identified adipokine suggested to link obesity with its comorbidities, especially insulin resistance, type 2 diabetes (T2D), and certain components of the metabolic syndrome. However, data, especially resulting from the clinical studies, are conflicting. In this review, we summarize up-to-date knowledge on RBP4's role in obesity, development of insulin resistance, and T2D. Special attention is given to studies on children and adolescents. We also discuss the role of possible confounding factors that should be taken into account when critically evaluating published studies or planning new studies on this exciting adipokine." @default.
• W2133792826 created "2016-06-24" @default.
• W2133792826 creator A5047788791 @default.
• W2133792826 creator A5060959515 @default.
• W2133792826 creator A5089547723 @default.
• W2133792826 date "2011-11-01" @default.
• W2133792826 modified "2023-09-23" @default.
• W2133792826 title "RBP4: a controversial adipokine" @default.
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• W2133792826 doi "https://doi.org/10.1530/eje-11-0431" @default.
• W2133792826 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21835764" @default.

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