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• W2133956305 abstract "Objectives We aimed to compare the differences in caries lesion changes when measured by QLF-D as fluorescence loss and by SS-OCT as lesion depth with respect to demineralized time, during formation of artificial early caries lesion. We also demonstrated that QLF-D and SS-OCT can be used effectively in monitoring the longitudinal progression of simulated caries lesions. Methods Ten bovine incisors were sectioned (5×4 mm) and embedded in epoxy resin. An acid-resistant nail varnish was applied to a part of the tooth surfaces to protect sound enamel (2×4 mm). To generate lesions, each specimen was immersed in 40 ml of a demineralizing gel for 20 days at 37°C. To measure mineral loss of the demineralized specimens, fluorescence loss (∆F, %) was measured by QLF-D and lesion depth (μm) was determined by SS-OCT from the captured cross-sectional image. All the specimens were analyzed daily by QLF-D image analysis software and SS-OCT image analysis program for 20 days. The repeated measures analysis of ∆F and lesion depth was used. The paired t-test was used to assess differences between each day. The correlation between ∆F and lesion depth was determined using the Pearson’s correlation coefficient. Results On the 5th, 10th, and 15th day, compared to baseline values, ∆F decreased in 12.7%, 25.0%, and 33.6% of the specimens, respectively, and the lesion depth increased in 9.9%, 16.0%, and 22.6% of the specimens, respectively. However, after 15 days, there was no change in the ∆F and lesion depth. High significant correlation was identified between the resultant values of ∆F obtained by QLF-D and those of lesion depth obtained by SS-OCT (r = ―0.811, P<0.0001). Conclusions The QLF-D and SS-OCT could detect subtle changes in mineral loss and lesion depth with respect to demineralized time. Furthermore, these devices were useful for monitoring changes in mineral amount and lesion depth." @default.
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• W2133956305 date "2014-01-01" @default.
• W2133956305 modified "2023-09-27" @default.
• W2133956305 title "Detection of early changes in caries lesion using QLF-D and OCT" @default.
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• W2133956305 doi "https://doi.org/10.11149/jkaoh.2014.38.1.10" @default.
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