SemOpenAlex |

SemOpenAlex

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2134037171> ?p ?o ?g. }

Showing items 1 to 100 of ±104 with 100 items per page.

W2134037171 endingPage "941" @default.
W2134037171 startingPage "933" @default.
W2134037171 abstract "The neuropeptide galanin (GAL) is found in neurons in the biliary tract of several species. We mapped the distribution of GAL-like immunoreactive nerve (GAL-LI) fibers in the sphincter of Oddi of the Australian brush-tailed possum by immunohistochemistry. The pharmacological effects of GAL in vitro and in vivo were studied by measuring sphincter of Oddi muscle strip contractility and transsphincteric flow, respectively. Muscle layers, and ganglionated and perivascular plexuses, contained GAL-LI nerve fibers. Exogenous GAL caused a concentration-dependent (10−9–10−6 M) increase in the spontaneous longitudinal but not circular muscle contractions. At 10−6 M GAL, contractile activity was elevated two- to fourfold. This response was tetrodotoxin insensitive but competitively inhibited by galantide (10−8–10−7 M). In vivo, intra-arterial bolus injections of GAL (100–1000 ng/kg), decreased transsphincteric flow, with a maximum reduction to 80.2 ± 6.8% of control. In conclusion, GAL appears to selectively stimulate longitudinally oriented sphincter of Oddi smooth muscle via a direct mechanism, which results in a modest reduction in transsphincteric flow." @default.
W2134037171 created "2016-06-24" @default.
W2134037171 creator A5016325648 @default.
W2134037171 creator A5019780497 @default.
W2134037171 creator A5037840112 @default.
W2134037171 creator A5053664013 @default.
W2134037171 creator A5073318594 @default.
W2134037171 date "1996-01-01" @default.
W2134037171 modified "2023-10-15" @default.
W2134037171 title "Galanin modulates sphincter of Oddi function in the Australian brush-tailed possum" @default.
W2134037171 cites W1964373371 @default.
W2134037171 cites W1965578455 @default.
W2134037171 cites W1966452363 @default.
W2134037171 cites W1967616884 @default.
W2134037171 cites W1972976241 @default.
W2134037171 cites W1975192104 @default.
W2134037171 cites W1978075056 @default.
W2134037171 cites W1984537109 @default.
W2134037171 cites W1997585172 @default.
W2134037171 cites W1999720135 @default.
W2134037171 cites W2000390819 @default.
W2134037171 cites W2027159024 @default.
W2134037171 cites W2027439932 @default.
W2134037171 cites W2030195234 @default.
W2134037171 cites W2038145345 @default.
W2134037171 cites W2074185076 @default.
W2134037171 cites W2079465733 @default.
W2134037171 cites W2086669245 @default.
W2134037171 cites W2088167629 @default.
W2134037171 cites W2089411167 @default.
W2134037171 cites W2108949956 @default.
W2134037171 cites W215190647 @default.
W2134037171 cites W2341027565 @default.
W2134037171 cites W260028236 @default.
W2134037171 doi "https://doi.org/10.1016/0196-9781(96)00147-7" @default.
W2134037171 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8899811" @default.
W2134037171 hasPublicationYear "1996" @default.
W2134037171 type Work @default.
W2134037171 sameAs 2134037171 @default.
W2134037171 citedByCount "18" @default.
W2134037171 countsByYear W21340371712012 @default.
W2134037171 countsByYear W21340371712013 @default.
W2134037171 countsByYear W21340371712014 @default.
W2134037171 countsByYear W21340371712016 @default.
W2134037171 countsByYear W21340371712018 @default.
W2134037171 countsByYear W21340371712023 @default.
W2134037171 crossrefType "journal-article" @default.
W2134037171 hasAuthorship W2134037171A5016325648 @default.
W2134037171 hasAuthorship W2134037171A5019780497 @default.
W2134037171 hasAuthorship W2134037171A5037840112 @default.
W2134037171 hasAuthorship W2134037171A5053664013 @default.
W2134037171 hasAuthorship W2134037171A5073318594 @default.
W2134037171 hasConcept C105702510 @default.
W2134037171 hasConcept C118303440 @default.
W2134037171 hasConcept C126322002 @default.
W2134037171 hasConcept C134018914 @default.
W2134037171 hasConcept C150903083 @default.
W2134037171 hasConcept C170493617 @default.
W2134037171 hasConcept C185592680 @default.
W2134037171 hasConcept C19519825 @default.
W2134037171 hasConcept C207001950 @default.
W2134037171 hasConcept C2776741303 @default.
W2134037171 hasConcept C2777891700 @default.
W2134037171 hasConcept C2780877482 @default.
W2134037171 hasConcept C39133596 @default.
W2134037171 hasConcept C71924100 @default.
W2134037171 hasConcept C86803240 @default.
W2134037171 hasConceptScore W2134037171C105702510 @default.
W2134037171 hasConceptScore W2134037171C118303440 @default.
W2134037171 hasConceptScore W2134037171C126322002 @default.
W2134037171 hasConceptScore W2134037171C134018914 @default.
W2134037171 hasConceptScore W2134037171C150903083 @default.
W2134037171 hasConceptScore W2134037171C170493617 @default.
W2134037171 hasConceptScore W2134037171C185592680 @default.
W2134037171 hasConceptScore W2134037171C19519825 @default.
W2134037171 hasConceptScore W2134037171C207001950 @default.
W2134037171 hasConceptScore W2134037171C2776741303 @default.
W2134037171 hasConceptScore W2134037171C2777891700 @default.
W2134037171 hasConceptScore W2134037171C2780877482 @default.
W2134037171 hasConceptScore W2134037171C39133596 @default.
W2134037171 hasConceptScore W2134037171C71924100 @default.
W2134037171 hasConceptScore W2134037171C86803240 @default.
W2134037171 hasIssue "6" @default.
W2134037171 hasLocation W21340371711 @default.
W2134037171 hasLocation W21340371712 @default.
W2134037171 hasOpenAccess W2134037171 @default.
W2134037171 hasPrimaryLocation W21340371711 @default.
W2134037171 hasRelatedWork W1571629474 @default.
W2134037171 hasRelatedWork W1994593453 @default.
W2134037171 hasRelatedWork W2014039316 @default.
W2134037171 hasRelatedWork W2050563506 @default.
W2134037171 hasRelatedWork W2055017397 @default.
W2134037171 hasRelatedWork W2070673985 @default.
W2134037171 hasRelatedWork W2078096231 @default.
W2134037171 hasRelatedWork W2086376537 @default.
W2134037171 hasRelatedWork W2136280470 @default.
W2134037171 hasRelatedWork W2884368152 @default.
W2134037171 hasVolume "17" @default.