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• W2134109964 abstract "Although the use of RRT to support critically ill patients with AKI has become routine, many of the fundamental questions regarding optimal management of RRT remain. Although absolute indications for initiating RRT, such as hyperkalemia and overt uremic symptoms, are well recognized, the optimal timing of therapy in patients without these indications continues to be a subject of debate. The selection of modality does not appear to have a major impact on mortality or recovery of kidney function. Selection of modality for renal support should therefore be based on local expertise and logistic factors, with the emphasis on ensuring that the treatment provided is the safest and most cost-efficient for the particular health setting. Finally, reasonable minimal standards for the delivered dose of therapy appear to have been identified; a process for local quality assurance and performance improvement should be implemented to ensure that these are achieved. The mortality associated with severe AKI remains unacceptably high; however there is little evidence to suggest that this mortality will be substantially altered by improvements in the delivery of renal support. Rather, we must be realistic in our expectations of what dialysis and hemofiltration can accomplish and vigorously pursue other strategies to improve the care of these patients." @default.
• W2134109964 created "2016-06-24" @default.
• W2134109964 creator A5025865647 @default.
• W2134109964 date "2013-01-01" @default.
• W2134109964 modified "2023-09-27" @default.
• W2134109964 title "Renal Replacement Therapy in Acute Kidney Injury" @default.
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• W2134109964 doi "https://doi.org/10.1053/j.ackd.2012.09.004" @default.
• W2134109964 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3531877" @default.
• W2134109964 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23265599" @default.
• W2134109964 hasPublicationYear "2013" @default.
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