FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2134214894> ?p ?o ?g. }

• W2134214894 abstract "The yeast Xanthophyllomyces dendrorhous synthesizes astaxanthin, a carotenoid with high commercial interest. The proposed biosynthetic route in this organism is isopentenyl-pyrophosphate (IPP) --> geranyleranyl pyrophosphate (GGPP) --> phytoene --> lycopene --> beta-carotene --> astaxanthin. Recently, it has been published that the conversion of beta-carotene into astaxanthin requires only one enzyme, astaxanthin synthase or CrtS, encoded by crtS gene. This enzyme belongs to the cytochrome P450 protein family.In this work, a crtR gene was isolated from X. dendrorhous yeast, which encodes a cytochrome P450 reductase (CPR) that provides CrtS with the necessary electrons for substrate oxygenation. We determined the structural organization of the crtR gene and its location in the yeast electrophoretic karyotype. Two transformants, CBSTr and T13, were obtained by deleting the crtR gene and inserting a hygromycin B resistance cassette. The carotenoid composition of the transformants was altered in relation to the wild type strain. CBSTr forms yellow colonies because it is unable to produce astaxanthin, hence accumulating beta-carotene. T13 forms pale colonies because its astaxanthin content is reduced and its beta-carotene content is increased.In addition to the crtS gene, X. dendrorhous requires a novel gene, crtR, for the conversion of beta-carotene to astaxanthin." @default.
• W2134214894 created "2016-06-24" @default.
• W2134214894 creator A5001729088 @default.
• W2134214894 creator A5010874761 @default.
• W2134214894 creator A5018681577 @default.
• W2134214894 creator A5024705447 @default.
• W2134214894 creator A5039375365 @default.
• W2134214894 creator A5047810254 @default.
• W2134214894 creator A5077608946 @default.
• W2134214894 creator A5077775619 @default.
• W2134214894 creator A5090656094 @default.
• W2134214894 date "2008-10-06" @default.
• W2134214894 modified "2023-09-30" @default.
• W2134214894 title "Cloning of the cytochrome p450 reductase (crtR) gene and its involvement in the astaxanthin biosynthesis of Xanthophyllomyces dendrorhous" @default.
• W2134214894 cites W1498020519 @default.
• W2134214894 cites W1519684776 @default.
• W2134214894 cites W1870962374 @default.
• W2134214894 cites W1912698848 @default.
• W2134214894 cites W1979646251 @default.
• W2134214894 cites W1987130890 @default.
• W2134214894 cites W1991440112 @default.
• W2134214894 cites W1994218934 @default.
• W2134214894 cites W2006352258 @default.
• W2134214894 cites W2006465601 @default.
• W2134214894 cites W2007332439 @default.
• W2134214894 cites W2017186312 @default.
• W2134214894 cites W2028201207 @default.
• W2134214894 cites W2034254870 @default.
• W2134214894 cites W2036068456 @default.
• W2134214894 cites W2060848640 @default.
• W2134214894 cites W2067352299 @default.
• W2134214894 cites W2071865335 @default.
• W2134214894 cites W2075925050 @default.
• W2134214894 cites W2076579091 @default.
• W2134214894 cites W2079458070 @default.
• W2134214894 cites W2080053967 @default.
• W2134214894 cites W2081282862 @default.
• W2134214894 cites W2081493686 @default.
• W2134214894 cites W2085901479 @default.
• W2134214894 cites W2095044970 @default.
• W2134214894 cites W2111304437 @default.
• W2134214894 cites W2125113432 @default.
• W2134214894 cites W2126405860 @default.
• W2134214894 cites W2134812217 @default.
• W2134214894 cites W2141667719 @default.
• W2134214894 cites W2142202544 @default.
• W2134214894 cites W2153810819 @default.
• W2134214894 cites W2158327382 @default.
• W2134214894 cites W2167364538 @default.
• W2134214894 cites W2169392014 @default.
• W2134214894 cites W4294216491 @default.
• W2134214894 cites W85796967 @default.
• W2134214894 cites W97293328 @default.
• W2134214894 doi "https://doi.org/10.1186/1471-2180-8-169" @default.
• W2134214894 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2575211" @default.
• W2134214894 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18837978" @default.
• W2134214894 hasPublicationYear "2008" @default.
• W2134214894 type Work @default.
• W2134214894 sameAs 2134214894 @default.
• W2134214894 citedByCount "71" @default.
• W2134214894 countsByYear W21342148942012 @default.
• W2134214894 countsByYear W21342148942013 @default.
• W2134214894 countsByYear W21342148942014 @default.
• W2134214894 countsByYear W21342148942015 @default.
• W2134214894 countsByYear W21342148942016 @default.
• W2134214894 countsByYear W21342148942017 @default.
• W2134214894 countsByYear W21342148942018 @default.
• W2134214894 countsByYear W21342148942019 @default.
• W2134214894 countsByYear W21342148942020 @default.
• W2134214894 countsByYear W21342148942021 @default.
• W2134214894 countsByYear W21342148942022 @default.
• W2134214894 countsByYear W21342148942023 @default.
• W2134214894 crossrefType "journal-article" @default.
• W2134214894 hasAuthorship W2134214894A5001729088 @default.
• W2134214894 hasAuthorship W2134214894A5010874761 @default.
• W2134214894 hasAuthorship W2134214894A5018681577 @default.
• W2134214894 hasAuthorship W2134214894A5024705447 @default.
• W2134214894 hasAuthorship W2134214894A5039375365 @default.
• W2134214894 hasAuthorship W2134214894A5047810254 @default.
• W2134214894 hasAuthorship W2134214894A5077608946 @default.
• W2134214894 hasAuthorship W2134214894A5077775619 @default.
• W2134214894 hasAuthorship W2134214894A5090656094 @default.
• W2134214894 hasBestOaLocation W21342148941 @default.
• W2134214894 hasConcept C104317684 @default.
• W2134214894 hasConcept C153911025 @default.
• W2134214894 hasConcept C2776824099 @default.
• W2134214894 hasConcept C2779222958 @default.
• W2134214894 hasConcept C2780022147 @default.
• W2134214894 hasConcept C2780962900 @default.
• W2134214894 hasConcept C28781525 @default.
• W2134214894 hasConcept C55493867 @default.
• W2134214894 hasConcept C86803240 @default.
• W2134214894 hasConceptScore W2134214894C104317684 @default.
• W2134214894 hasConceptScore W2134214894C153911025 @default.
• W2134214894 hasConceptScore W2134214894C2776824099 @default.
• W2134214894 hasConceptScore W2134214894C2779222958 @default.
• W2134214894 hasConceptScore W2134214894C2780022147 @default.
• W2134214894 hasConceptScore W2134214894C2780962900 @default.
• W2134214894 hasConceptScore W2134214894C28781525 @default.
• W2134214894 hasConceptScore W2134214894C55493867 @default.

• next