Matches in SemOpenAlex for { <https://semopenalex.org/work/W2134221373> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2134221373 endingPage "112" @default.
- W2134221373 startingPage "104" @default.
- W2134221373 abstract "Left ventricular heart function and its response to long-term estrogen replacement therapy was assessed in 30 postmenopausal women, 20 of whom had modest to severe hot flushes and 10 of whom had never had them. Continuous transdermal estradiol was given to women who had surgically induced menopause, and a combination of transdermal estradiol and sequential medroxyprogesterone acetate was given to those who had spontaneous menopause. Left ventricular systolic and diastolic function was evaluated by complete two-dimensional M-mode and pulsed Doppler echocardiography before and after 6 and 12 months of therapy. The parameters assessed were: systolic and diastolic blood pressure, heart rate, cardiac septal and posterior wall dimensions, left ventricular end-systolic and end-diastolic dimensions and volumes, ejection fraction (EF), ejection time, peak left ventricular outflow velocity (PFV), flow velocity integral (FVI), acceleration time (AT), mean acceleration of systolic flow (MA), duration of early and late filling phase, peak velocity of the early (E) and late (A) mitral flow, and A/E velocity ratio. Although no difference in chamber and wall dimensions between flushers and non-flushers was found, women with hot flushes had lower (not significantly) EF, PFV, FVI, MA, blood pressure and heart rate before therapy. Twelve-month estrogen replacement therapy significantly reduced cardiac wall dimensions and improved systolic function in both flushers and non-flushers. However, stroke volume, EF and MA were increased whereas systolic blood pressure and heart rate were decreased more in flushers. Also, the increase in E mitralflow and decrease in A/E were more pronounced in flushers. Thus, although estrogen replacement therapy significantly improves heart function in healthy postmenopausal women, there appears to be some minor differences in response between flushers and non-flushers." @default.
- W2134221373 created "2016-06-24" @default.
- W2134221373 creator A5006346513 @default.
- W2134221373 creator A5013405829 @default.
- W2134221373 creator A5041939938 @default.
- W2134221373 creator A5088777014 @default.
- W2134221373 date "1999-01-01" @default.
- W2134221373 modified "2023-10-16" @default.
- W2134221373 title "Effect of estrogen replacement therapy on cardiac function in postmenopausal women with and without flushes" @default.
- W2134221373 cites W1964407044 @default.
- W2134221373 cites W1974936785 @default.
- W2134221373 cites W1978658082 @default.
- W2134221373 cites W1979442189 @default.
- W2134221373 cites W1980514293 @default.
- W2134221373 cites W1980574994 @default.
- W2134221373 cites W1985360161 @default.
- W2134221373 cites W2004668568 @default.
- W2134221373 cites W2005520585 @default.
- W2134221373 cites W2023348873 @default.
- W2134221373 cites W2045517298 @default.
- W2134221373 cites W2054153594 @default.
- W2134221373 cites W2057009504 @default.
- W2134221373 cites W2060204800 @default.
- W2134221373 cites W2062126838 @default.
- W2134221373 cites W2084813778 @default.
- W2134221373 cites W2089939005 @default.
- W2134221373 cites W2113083707 @default.
- W2134221373 cites W2113509381 @default.
- W2134221373 doi "https://doi.org/10.3109/09513599909167541" @default.
- W2134221373 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10399055" @default.
- W2134221373 hasPublicationYear "1999" @default.
- W2134221373 type Work @default.
- W2134221373 sameAs 2134221373 @default.
- W2134221373 citedByCount "19" @default.
- W2134221373 countsByYear W21342213732012 @default.
- W2134221373 countsByYear W21342213732014 @default.
- W2134221373 countsByYear W21342213732015 @default.
- W2134221373 countsByYear W21342213732016 @default.
- W2134221373 countsByYear W21342213732022 @default.
- W2134221373 crossrefType "journal-article" @default.
- W2134221373 hasAuthorship W2134221373A5006346513 @default.
- W2134221373 hasAuthorship W2134221373A5013405829 @default.
- W2134221373 hasAuthorship W2134221373A5041939938 @default.
- W2134221373 hasAuthorship W2134221373A5088777014 @default.
- W2134221373 hasConcept C111566952 @default.
- W2134221373 hasConcept C126322002 @default.
- W2134221373 hasConcept C139940330 @default.
- W2134221373 hasConcept C164705383 @default.
- W2134221373 hasConcept C2776306185 @default.
- W2134221373 hasConcept C2777164284 @default.
- W2134221373 hasConcept C2777953023 @default.
- W2134221373 hasConcept C2778198053 @default.
- W2134221373 hasConcept C2778562196 @default.
- W2134221373 hasConcept C2778921608 @default.
- W2134221373 hasConcept C2779279991 @default.
- W2134221373 hasConcept C2780159708 @default.
- W2134221373 hasConcept C57900726 @default.
- W2134221373 hasConcept C71924100 @default.
- W2134221373 hasConcept C78085059 @default.
- W2134221373 hasConcept C80461066 @default.
- W2134221373 hasConcept C84393581 @default.
- W2134221373 hasConceptScore W2134221373C111566952 @default.
- W2134221373 hasConceptScore W2134221373C126322002 @default.
- W2134221373 hasConceptScore W2134221373C139940330 @default.
- W2134221373 hasConceptScore W2134221373C164705383 @default.
- W2134221373 hasConceptScore W2134221373C2776306185 @default.
- W2134221373 hasConceptScore W2134221373C2777164284 @default.
- W2134221373 hasConceptScore W2134221373C2777953023 @default.
- W2134221373 hasConceptScore W2134221373C2778198053 @default.
- W2134221373 hasConceptScore W2134221373C2778562196 @default.
- W2134221373 hasConceptScore W2134221373C2778921608 @default.
- W2134221373 hasConceptScore W2134221373C2779279991 @default.
- W2134221373 hasConceptScore W2134221373C2780159708 @default.
- W2134221373 hasConceptScore W2134221373C57900726 @default.
- W2134221373 hasConceptScore W2134221373C71924100 @default.
- W2134221373 hasConceptScore W2134221373C78085059 @default.
- W2134221373 hasConceptScore W2134221373C80461066 @default.
- W2134221373 hasConceptScore W2134221373C84393581 @default.
- W2134221373 hasIssue "2" @default.
- W2134221373 hasLocation W21342213731 @default.
- W2134221373 hasLocation W21342213732 @default.
- W2134221373 hasOpenAccess W2134221373 @default.
- W2134221373 hasPrimaryLocation W21342213731 @default.
- W2134221373 hasRelatedWork W1981675155 @default.
- W2134221373 hasRelatedWork W2020785319 @default.
- W2134221373 hasRelatedWork W2032155215 @default.
- W2134221373 hasRelatedWork W2316342240 @default.
- W2134221373 hasRelatedWork W2347245660 @default.
- W2134221373 hasRelatedWork W2892714137 @default.
- W2134221373 hasRelatedWork W2895572986 @default.
- W2134221373 hasRelatedWork W2999818207 @default.
- W2134221373 hasRelatedWork W4302760406 @default.
- W2134221373 hasRelatedWork W3023986520 @default.
- W2134221373 hasVolume "13" @default.
- W2134221373 isParatext "false" @default.
- W2134221373 isRetracted "false" @default.
- W2134221373 magId "2134221373" @default.
- W2134221373 workType "article" @default.