Matches in SemOpenAlex for { <https://semopenalex.org/work/W2134252080> ?p ?o ?g. }
- W2134252080 endingPage "3707" @default.
- W2134252080 startingPage "3693" @default.
- W2134252080 abstract "During meiosis II in Saccharomyces cerevisiae, the cytoplasmic face of the spindle pole body, referred to as the meiosis II outer plaque (MOP), is modified in both composition and structure to become the initiation site for de novo formation of a membrane called the prospore membrane. The MOP serves as a docking complex for precursor vesicles that are targeted to its surface. Using fluorescence resonance energy transfer analysis, the orientation of coiled-coil proteins within the MOP has been determined. The N-termini of two proteins, Mpc54p and Spo21p, were oriented toward the outer surface of the structure. Mutations in the N-terminus of Mpc54p resulted in a unique phenotype: precursor vesicles loosely tethered to the MOP but did not contact its surface. Thus, these mpc54 mutants separate the steps of vesicle association and docking. Using these mpc54 mutants, we determined that recruitment of the Rab GTPase Sec4p, as well as the exocyst components Sec3p and Sec8p, to the precursor vesicles requires vesicle docking to the MOP. This suggests that the MOP promotes membrane formation both by localization of precursor vesicles to a particular site and by recruitment of a second tethering complex, the exocyst, that stimulates downstream events of fusion." @default.
- W2134252080 created "2016-06-24" @default.
- W2134252080 creator A5022826364 @default.
- W2134252080 creator A5040078355 @default.
- W2134252080 creator A5065008527 @default.
- W2134252080 creator A5066592986 @default.
- W2134252080 creator A5078156454 @default.
- W2134252080 creator A5080231073 @default.
- W2134252080 creator A5087355354 @default.
- W2134252080 date "2010-11-01" @default.
- W2134252080 modified "2023-09-23" @default.
- W2134252080 title "Vesicle Docking to the Spindle Pole Body Is Necessary to Recruit the Exocyst During Membrane Formation in<i>Saccharomyces cerevisiae</i>" @default.
- W2134252080 cites W128906662 @default.
- W2134252080 cites W1492059346 @default.
- W2134252080 cites W1508614407 @default.
- W2134252080 cites W1520187505 @default.
- W2134252080 cites W1663920100 @default.
- W2134252080 cites W1891504318 @default.
- W2134252080 cites W1910653415 @default.
- W2134252080 cites W1939706863 @default.
- W2134252080 cites W1966072209 @default.
- W2134252080 cites W1974054235 @default.
- W2134252080 cites W1979758365 @default.
- W2134252080 cites W1999744850 @default.
- W2134252080 cites W2003345155 @default.
- W2134252080 cites W2010478335 @default.
- W2134252080 cites W2011793938 @default.
- W2134252080 cites W2013026243 @default.
- W2134252080 cites W2018215453 @default.
- W2134252080 cites W2030076269 @default.
- W2134252080 cites W2030445913 @default.
- W2134252080 cites W2030645367 @default.
- W2134252080 cites W2032817187 @default.
- W2134252080 cites W2040108963 @default.
- W2134252080 cites W2055043387 @default.
- W2134252080 cites W2056182641 @default.
- W2134252080 cites W2060337011 @default.
- W2134252080 cites W2065593669 @default.
- W2134252080 cites W2070963888 @default.
- W2134252080 cites W2075240236 @default.
- W2134252080 cites W2082386832 @default.
- W2134252080 cites W2086456903 @default.
- W2134252080 cites W2093081532 @default.
- W2134252080 cites W2095506400 @default.
- W2134252080 cites W2096005517 @default.
- W2134252080 cites W2102019596 @default.
- W2134252080 cites W2106457287 @default.
- W2134252080 cites W2117571939 @default.
- W2134252080 cites W2119905730 @default.
- W2134252080 cites W2131064855 @default.
- W2134252080 cites W2135021919 @default.
- W2134252080 cites W2136125398 @default.
- W2134252080 cites W2141709165 @default.
- W2134252080 cites W2143652092 @default.
- W2134252080 cites W2144407275 @default.
- W2134252080 cites W2148939860 @default.
- W2134252080 cites W2150341205 @default.
- W2134252080 cites W2150470031 @default.
- W2134252080 cites W2152231771 @default.
- W2134252080 cites W2154425220 @default.
- W2134252080 cites W2163795610 @default.
- W2134252080 cites W2164433356 @default.
- W2134252080 cites W2165595538 @default.
- W2134252080 cites W304139261 @default.
- W2134252080 doi "https://doi.org/10.1091/mbc.e10-07-0563" @default.
- W2134252080 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2965686" @default.
- W2134252080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20826607" @default.
- W2134252080 hasPublicationYear "2010" @default.
- W2134252080 type Work @default.
- W2134252080 sameAs 2134252080 @default.
- W2134252080 citedByCount "20" @default.
- W2134252080 countsByYear W21342520802012 @default.
- W2134252080 countsByYear W21342520802013 @default.
- W2134252080 countsByYear W21342520802014 @default.
- W2134252080 countsByYear W21342520802016 @default.
- W2134252080 countsByYear W21342520802017 @default.
- W2134252080 countsByYear W21342520802019 @default.
- W2134252080 countsByYear W21342520802020 @default.
- W2134252080 countsByYear W21342520802021 @default.
- W2134252080 countsByYear W21342520802023 @default.
- W2134252080 crossrefType "journal-article" @default.
- W2134252080 hasAuthorship W2134252080A5022826364 @default.
- W2134252080 hasAuthorship W2134252080A5040078355 @default.
- W2134252080 hasAuthorship W2134252080A5065008527 @default.
- W2134252080 hasAuthorship W2134252080A5066592986 @default.
- W2134252080 hasAuthorship W2134252080A5078156454 @default.
- W2134252080 hasAuthorship W2134252080A5080231073 @default.
- W2134252080 hasAuthorship W2134252080A5087355354 @default.
- W2134252080 hasBestOaLocation W21342520802 @default.
- W2134252080 hasConcept C103038307 @default.
- W2134252080 hasConcept C130316041 @default.
- W2134252080 hasConcept C148785051 @default.
- W2134252080 hasConcept C190062978 @default.
- W2134252080 hasConcept C196330066 @default.
- W2134252080 hasConcept C2777576037 @default.
- W2134252080 hasConcept C2778448323 @default.
- W2134252080 hasConcept C2779222958 @default.
- W2134252080 hasConcept C2780298669 @default.