Matches in SemOpenAlex for { <https://semopenalex.org/work/W2134392979> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2134392979 endingPage "506" @default.
- W2134392979 startingPage "497" @default.
- W2134392979 abstract "Recent progress in sensor technology has led to the development and application of electronic taste sensing systems. Especially taste prediction of pharmaceutical formulations is a matter of particular interest and is increasingly performed using electronic tongues. Several studies have dealt with electronic tongues before, but an analytical approach describing successfully conducted qualification has not been reported yet. Performance qualification of the taste sensing system SA402B (Insent Inc., Atsugi-chi, Japan) equipped with seven lipid membrane sensors was undertaken with special regard to bitter taste assessment. These sensors represent the gustatory stimuli bitterness, umami, saltiness, sourness, and the nociceptive sensation astringency. Specificity, linearity, range, accuracy, precision, detection and quantitation limit as well as robustness were established for each sensor type referring to ICH guideline Q2 (R1). Some items mentioned in the guideline were applicable whereas others had to be modified due to differences of the system to other commonly used analytical techniques. Quinine hydrochloride being one of the bitterest drugs served as model substance. A large range of linearity (0.01–100 mM) with corresponding precision (RSD < 4%) was found for most sensors. One sensor had a lower detection threshold (0.0025 mM) for quinine hydrochloride than humans typically have. Different methods for determination of detection and quantitation limits were implemented and discussed with respect to rationality and feasibility. Therefore the approach based on visual evaluation was found as most adequate. An adapted guidance following ICH guideline Q2 was developed serving qualification of taste sensing systems in the future." @default.
- W2134392979 created "2016-06-24" @default.
- W2134392979 creator A5033603164 @default.
- W2134392979 creator A5053426503 @default.
- W2134392979 creator A5065080932 @default.
- W2134392979 creator A5067053823 @default.
- W2134392979 date "2010-02-01" @default.
- W2134392979 modified "2023-10-16" @default.
- W2134392979 title "Performance qualification of an electronic tongue based on ICH guideline Q2" @default.
- W2134392979 cites W1971464404 @default.
- W2134392979 cites W1986466801 @default.
- W2134392979 cites W2002585391 @default.
- W2134392979 cites W2006473565 @default.
- W2134392979 cites W2008129571 @default.
- W2134392979 cites W2018026400 @default.
- W2134392979 cites W2022265136 @default.
- W2134392979 cites W2029288219 @default.
- W2134392979 cites W2044053760 @default.
- W2134392979 cites W2047605109 @default.
- W2134392979 cites W2067156932 @default.
- W2134392979 cites W2074927293 @default.
- W2134392979 cites W2092557227 @default.
- W2134392979 cites W2110949192 @default.
- W2134392979 cites W2136311118 @default.
- W2134392979 cites W2156145621 @default.
- W2134392979 cites W4255752163 @default.
- W2134392979 doi "https://doi.org/10.1016/j.jpba.2009.09.029" @default.
- W2134392979 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19853397" @default.
- W2134392979 hasPublicationYear "2010" @default.
- W2134392979 type Work @default.
- W2134392979 sameAs 2134392979 @default.
- W2134392979 citedByCount "86" @default.
- W2134392979 countsByYear W21343929792012 @default.
- W2134392979 countsByYear W21343929792013 @default.
- W2134392979 countsByYear W21343929792014 @default.
- W2134392979 countsByYear W21343929792015 @default.
- W2134392979 countsByYear W21343929792016 @default.
- W2134392979 countsByYear W21343929792017 @default.
- W2134392979 countsByYear W21343929792018 @default.
- W2134392979 countsByYear W21343929792019 @default.
- W2134392979 countsByYear W21343929792020 @default.
- W2134392979 countsByYear W21343929792021 @default.
- W2134392979 countsByYear W21343929792022 @default.
- W2134392979 countsByYear W21343929792023 @default.
- W2134392979 crossrefType "journal-article" @default.
- W2134392979 hasAuthorship W2134392979A5033603164 @default.
- W2134392979 hasAuthorship W2134392979A5053426503 @default.
- W2134392979 hasAuthorship W2134392979A5065080932 @default.
- W2134392979 hasAuthorship W2134392979A5067053823 @default.
- W2134392979 hasConcept C119128265 @default.
- W2134392979 hasConcept C121332964 @default.
- W2134392979 hasConcept C142724271 @default.
- W2134392979 hasConcept C162244969 @default.
- W2134392979 hasConcept C185592680 @default.
- W2134392979 hasConcept C2776946002 @default.
- W2134392979 hasConcept C2780182762 @default.
- W2134392979 hasConcept C3020017864 @default.
- W2134392979 hasConcept C31903555 @default.
- W2134392979 hasConcept C43617362 @default.
- W2134392979 hasConcept C62520636 @default.
- W2134392979 hasConcept C71924100 @default.
- W2134392979 hasConcept C77170095 @default.
- W2134392979 hasConcept C8868529 @default.
- W2134392979 hasConceptScore W2134392979C119128265 @default.
- W2134392979 hasConceptScore W2134392979C121332964 @default.
- W2134392979 hasConceptScore W2134392979C142724271 @default.
- W2134392979 hasConceptScore W2134392979C162244969 @default.
- W2134392979 hasConceptScore W2134392979C185592680 @default.
- W2134392979 hasConceptScore W2134392979C2776946002 @default.
- W2134392979 hasConceptScore W2134392979C2780182762 @default.
- W2134392979 hasConceptScore W2134392979C3020017864 @default.
- W2134392979 hasConceptScore W2134392979C31903555 @default.
- W2134392979 hasConceptScore W2134392979C43617362 @default.
- W2134392979 hasConceptScore W2134392979C62520636 @default.
- W2134392979 hasConceptScore W2134392979C71924100 @default.
- W2134392979 hasConceptScore W2134392979C77170095 @default.
- W2134392979 hasConceptScore W2134392979C8868529 @default.
- W2134392979 hasIssue "3" @default.
- W2134392979 hasLocation W21343929791 @default.
- W2134392979 hasLocation W21343929792 @default.
- W2134392979 hasOpenAccess W2134392979 @default.
- W2134392979 hasPrimaryLocation W21343929791 @default.
- W2134392979 hasRelatedWork W1021693813 @default.
- W2134392979 hasRelatedWork W1124642266 @default.
- W2134392979 hasRelatedWork W2082567022 @default.
- W2134392979 hasRelatedWork W2353851779 @default.
- W2134392979 hasRelatedWork W2919199934 @default.
- W2134392979 hasRelatedWork W2972261947 @default.
- W2134392979 hasRelatedWork W3006795590 @default.
- W2134392979 hasRelatedWork W3130922612 @default.
- W2134392979 hasRelatedWork W3195536148 @default.
- W2134392979 hasRelatedWork W4387392684 @default.
- W2134392979 hasVolume "51" @default.
- W2134392979 isParatext "false" @default.
- W2134392979 isRetracted "false" @default.
- W2134392979 magId "2134392979" @default.
- W2134392979 workType "article" @default.