FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2134422416> ?p ?o ?g. }

• W2134422416 endingPage "281" @default.
• W2134422416 startingPage "273" @default.
• W2134422416 abstract "Bombesin (BN) interacts with two mammalian receptor subtypes termed gastrin-releasing peptide (GRP)-preferring (GRP-R) and neuromedin B (NMB)-preferring (NMB-R) that may mediate the satiety action of BN. We examined the feeding behavior of mice that were deficient in the GRP-R (GRP-R KO) to assess the overall contribution of this receptor subtype in the feeding actions of BN-related peptides. GRP-R KO mice failed to suppress glucose intake in response to systemically administered BN and GRP(18-27), whereas both peptides elicited a potent reduction of intake in wild-type (WT) mice. Neither GRP-R KO nor WT mice suppressed glucose intake following NMB administration. Unlike the impaired responses to BN-like peptides, the feeding inhibitory action of cholecystokinin was enhanced in GRP-R KO mice. Consistent with behavioral results, GRP-R KO mice also exhibited a reduction in c-Fos immunoreactivity in the nucleus of the solitary tract (NTS) and paraventricular nucleus (PVN) following peripheral administration of BN. An evaluation of meal patterns showed that GRP-R KO mice ate significantly more at each meal than WT mice, although total 24 h food consumption was equivalent. A long-term analysis of body weight revealed a significant elevation in GRP-R KO mice compared with WT littermates beginning at 45 weeks of age. These data suggest that the GRP-R mediates the feeding effects of BN-like peptides and participates in the termination of meals in mice." @default.
• W2134422416 created "2016-06-24" @default.
• W2134422416 creator A5002600436 @default.
• W2134422416 creator A5014769763 @default.
• W2134422416 creator A5025963512 @default.
• W2134422416 creator A5032349757 @default.
• W2134422416 creator A5043150953 @default.
• W2134422416 creator A5056129068 @default.
• W2134422416 date "2002-08-01" @default.
• W2134422416 modified "2023-10-14" @default.
• W2134422416 title "Disruptions in feeding and body weight control in gastrin-releasing peptide receptor deficient mice" @default.
• W2134422416 cites W1522048223 @default.
• W2134422416 cites W1537449868 @default.
• W2134422416 cites W1718598015 @default.
• W2134422416 cites W1735099752 @default.
• W2134422416 cites W1843346528 @default.
• W2134422416 cites W1966400534 @default.
• W2134422416 cites W1985132004 @default.
• W2134422416 cites W2010704106 @default.
• W2134422416 cites W2015570154 @default.
• W2134422416 cites W2023063407 @default.
• W2134422416 cites W2023660643 @default.
• W2134422416 cites W2028388432 @default.
• W2134422416 cites W2031526127 @default.
• W2134422416 cites W2032276726 @default.
• W2134422416 cites W2051628512 @default.
• W2134422416 cites W2057370521 @default.
• W2134422416 cites W2065571239 @default.
• W2134422416 cites W2068484878 @default.
• W2134422416 cites W2081230878 @default.
• W2134422416 cites W210896705 @default.
• W2134422416 cites W2118175636 @default.
• W2134422416 cites W2133314507 @default.
• W2134422416 cites W2137848795 @default.
• W2134422416 cites W2139996880 @default.
• W2134422416 cites W2156103946 @default.
• W2134422416 cites W2209635166 @default.
• W2134422416 cites W2286651703 @default.
• W2134422416 cites W2506550940 @default.
• W2134422416 doi "https://doi.org/10.1677/joe.0.1740273" @default.
• W2134422416 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12176666" @default.
• W2134422416 hasPublicationYear "2002" @default.
• W2134422416 type Work @default.
• W2134422416 sameAs 2134422416 @default.
• W2134422416 citedByCount "63" @default.
• W2134422416 countsByYear W21344224162012 @default.
• W2134422416 countsByYear W21344224162013 @default.
• W2134422416 countsByYear W21344224162014 @default.
• W2134422416 countsByYear W21344224162015 @default.
• W2134422416 countsByYear W21344224162016 @default.
• W2134422416 countsByYear W21344224162017 @default.
• W2134422416 countsByYear W21344224162019 @default.
• W2134422416 countsByYear W21344224162021 @default.
• W2134422416 countsByYear W21344224162022 @default.
• W2134422416 countsByYear W21344224162023 @default.
• W2134422416 crossrefType "journal-article" @default.
• W2134422416 hasAuthorship W2134422416A5002600436 @default.
• W2134422416 hasAuthorship W2134422416A5014769763 @default.
• W2134422416 hasAuthorship W2134422416A5025963512 @default.
• W2134422416 hasAuthorship W2134422416A5032349757 @default.
• W2134422416 hasAuthorship W2134422416A5043150953 @default.
• W2134422416 hasAuthorship W2134422416A5056129068 @default.
• W2134422416 hasBestOaLocation W21344224161 @default.
• W2134422416 hasConcept C118303440 @default.
• W2134422416 hasConcept C126322002 @default.
• W2134422416 hasConcept C134018914 @default.
• W2134422416 hasConcept C170493617 @default.
• W2134422416 hasConcept C185592680 @default.
• W2134422416 hasConcept C2776998989 @default.
• W2134422416 hasConcept C2777593968 @default.
• W2134422416 hasConcept C2778345441 @default.
• W2134422416 hasConcept C2778448772 @default.
• W2134422416 hasConcept C2779281246 @default.
• W2134422416 hasConcept C2780512811 @default.
• W2134422416 hasConcept C2780838160 @default.
• W2134422416 hasConcept C55493867 @default.
• W2134422416 hasConcept C71924100 @default.
• W2134422416 hasConcept C86803240 @default.
• W2134422416 hasConceptScore W2134422416C118303440 @default.
• W2134422416 hasConceptScore W2134422416C126322002 @default.
• W2134422416 hasConceptScore W2134422416C134018914 @default.
• W2134422416 hasConceptScore W2134422416C170493617 @default.
• W2134422416 hasConceptScore W2134422416C185592680 @default.
• W2134422416 hasConceptScore W2134422416C2776998989 @default.
• W2134422416 hasConceptScore W2134422416C2777593968 @default.
• W2134422416 hasConceptScore W2134422416C2778345441 @default.
• W2134422416 hasConceptScore W2134422416C2778448772 @default.
• W2134422416 hasConceptScore W2134422416C2779281246 @default.
• W2134422416 hasConceptScore W2134422416C2780512811 @default.
• W2134422416 hasConceptScore W2134422416C2780838160 @default.
• W2134422416 hasConceptScore W2134422416C55493867 @default.
• W2134422416 hasConceptScore W2134422416C71924100 @default.
• W2134422416 hasConceptScore W2134422416C86803240 @default.
• W2134422416 hasIssue "2" @default.
• W2134422416 hasLocation W21344224161 @default.
• W2134422416 hasLocation W21344224162 @default.
• W2134422416 hasLocation W21344224163 @default.
• W2134422416 hasOpenAccess W2134422416 @default.

• next