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• W2134444484 startingPage "3609" @default.
• W2134444484 abstract "Retroviral Gag proteins direct virus particle assembly from the plasma membrane (PM). Phosphatidylinositol-(4,5)-bisphosphate [PI(4,5)P(2)] plays a role in PM targeting of several retroviral Gag proteins. Here we report that depletion of intracellular PI(4,5)P(2) and phosphatidylinositol-(3,4,5)-triphosphate [PI(3,4,5)P(3)] levels impaired Rous sarcoma virus (RSV) Gag PM localization. Gag mutants deficient in nuclear trafficking were less sensitive to reduction of intracellular PI(4,5)P(2) and PI(3,4,5)P(3), suggesting a possible connection between Gag nuclear trafficking and phosphoinositide-dependent PM targeting." @default.
• W2134444484 created "2016-06-24" @default.
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• W2134444484 creator A5054735839 @default.
• W2134444484 date "2013-03-15" @default.
• W2134444484 modified "2023-10-13" @default.
• W2134444484 title "Alterations in the MA and NC Domains Modulate Phosphoinositide-Dependent Plasma Membrane Localization of the Rous Sarcoma Virus Gag Protein" @default.
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• W2134444484 doi "https://doi.org/10.1128/jvi.03059-12" @default.
• W2134444484 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3592118" @default.
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