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• W2134467508 endingPage "8815" @default.
• W2134467508 startingPage "8809" @default.
• W2134467508 abstract "Aryl-fused 2-azabicyclo[2.2.2]octanes were prepared by a novel sequence of Cu-catalyzed three-component coupling of diversely substituted N-benzyl o-bromoaryl imines with methacryloyl chloride and vinyltributyl stannane followed by Pd-catalyzed Heck annulation. Subsequent diversification of the aryl-fused 2-azabicyclo[2.2.2]octane core was achieved by attaching a flexible linker and a potential second pharmacophore via Ru-catalyzed cross-metathesis and a nucleophilic substitution." @default.
• W2134467508 created "2016-06-24" @default.
• W2134467508 creator A5050389619 @default.
• W2134467508 creator A5068823215 @default.
• W2134467508 date "2013-08-13" @default.
• W2134467508 modified "2023-09-29" @default.
• W2134467508 title "Modular Strategy for the Synthesis of Functionalized Aryl-Fused Azabicyclo[2.2.2]octanes via Sequential Cu/Pd/Ru Catalysis" @default.
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• W2134467508 doi "https://doi.org/10.1021/jo400974k" @default.
• W2134467508 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23941387" @default.
• W2134467508 hasPublicationYear "2013" @default.
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