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- W2134672144 abstract "Two transcription initiation sites have been identified in the mouse μ-opioid receptor (MOR) gene at approximately −793 and −268 upstream of the translation start site. To test if the MOR gene contains two functional promoters, chimeric constructs of mouse MOR deletion fragments, fused to a luciferase reporter gene, were transiently transfected into the neuroblastoma cell line SK-N-SH, a MOR-expressing cell line, and two MOR-non-expressing cell lines. Results from transient transfection assays confirmed the existence of two functional independent promoters in the mouse MOR gene, and also revealed that the region from −1337 to −93 does not contain all the elements necessary to confer tissue-specific expression of the MOR gene." @default.
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- W2134672144 date "1997-09-01" @default.
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- W2134672144 title "Transcription of the mouse μ-opioid receptor gene is regulated by two promoters" @default.
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- W2134672144 doi "https://doi.org/10.1016/s0006-8993(97)00854-8" @default.
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