FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2134675585> ?p ?o ?g. }

• W2134675585 endingPage "4683" @default.
• W2134675585 startingPage "4676" @default.
• W2134675585 abstract "Neural stem/progenitor cells (NSPCs) hold great promise in regenerative medicine; however, controlling their differentiation to a desired phenotype within a defined matrix is challenging. To guide the differentiation of NSPCs, we first created a cell-adhesive matrix of agarose modified with glycine-arginine-glycine-aspartic acid-serine (GRGDS) and then demonstrated the multipotentiality of NSPCs to differentiate to the three primary cell types of the central nervous system on this matrix: neurons, oligodendrocytes and astrocytes. We then examined whether immobilized platelet derived growth factor AA (PDGF-AA) would promote differentiation similarly to the same soluble factor and found similar percentages of NSPCs differentiated to oligodendrocytes as determined by immunohistochemistry (IHC) and quantitative reverse transcription-polymerase chain reaction (qRT-PCR). Interestingly, the gene expression of the differentiated oligodendrocytes was similar for 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) but different for myelin oligodendrocyte glycoprotein (MOG) in the presence of soluble PDGF-AA vs. immobilized PDGF-AA. These results demonstrate for the first time, that it is possible to control the differentiation of NSPCs, and specifically to oligodendrocytes, in cell-adhesive matrices with immobilized PDGF-AA." @default.
• W2134675585 created "2016-06-24" @default.
• W2134675585 creator A5003222708 @default.
• W2134675585 creator A5017899525 @default.
• W2134675585 creator A5022555743 @default.
• W2134675585 creator A5045900479 @default.
• W2134675585 date "2008-12-01" @default.
• W2134675585 modified "2023-10-17" @default.
• W2134675585 title "The effect of immobilized platelet derived growth factor AA on neural stem/progenitor cell differentiation on cell-adhesive hydrogels" @default.
• W2134675585 cites W1598459162 @default.
• W2134675585 cites W1643680178 @default.
• W2134675585 cites W1898365565 @default.
• W2134675585 cites W1970576706 @default.
• W2134675585 cites W1971249619 @default.
• W2134675585 cites W1972914996 @default.
• W2134675585 cites W1977633829 @default.
• W2134675585 cites W1981722629 @default.
• W2134675585 cites W1985925404 @default.
• W2134675585 cites W2018818236 @default.
• W2134675585 cites W2019270281 @default.
• W2134675585 cites W2024568036 @default.
• W2134675585 cites W2030508161 @default.
• W2134675585 cites W2039814124 @default.
• W2134675585 cites W2047134067 @default.
• W2134675585 cites W2048058951 @default.
• W2134675585 cites W2052262017 @default.
• W2134675585 cites W2057669829 @default.
• W2134675585 cites W2057853736 @default.
• W2134675585 cites W2062839477 @default.
• W2134675585 cites W2066465530 @default.
• W2134675585 cites W2066632925 @default.
• W2134675585 cites W2075815684 @default.
• W2134675585 cites W2084652820 @default.
• W2134675585 cites W2086641148 @default.
• W2134675585 cites W2089735370 @default.
• W2134675585 cites W2092471457 @default.
• W2134675585 cites W2116800744 @default.
• W2134675585 cites W2125650861 @default.
• W2134675585 cites W2145925994 @default.
• W2134675585 cites W2148625728 @default.
• W2134675585 cites W2168811660 @default.
• W2134675585 cites W2418430577 @default.
• W2134675585 cites W4239272659 @default.
• W2134675585 doi "https://doi.org/10.1016/j.biomaterials.2008.08.018" @default.
• W2134675585 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18801569" @default.
• W2134675585 hasPublicationYear "2008" @default.
• W2134675585 type Work @default.
• W2134675585 sameAs 2134675585 @default.
• W2134675585 citedByCount "84" @default.
• W2134675585 countsByYear W21346755852012 @default.
• W2134675585 countsByYear W21346755852013 @default.
• W2134675585 countsByYear W21346755852014 @default.
• W2134675585 countsByYear W21346755852015 @default.
• W2134675585 countsByYear W21346755852016 @default.
• W2134675585 countsByYear W21346755852017 @default.
• W2134675585 countsByYear W21346755852018 @default.
• W2134675585 countsByYear W21346755852019 @default.
• W2134675585 countsByYear W21346755852020 @default.
• W2134675585 countsByYear W21346755852021 @default.
• W2134675585 countsByYear W21346755852023 @default.
• W2134675585 crossrefType "journal-article" @default.
• W2134675585 hasAuthorship W2134675585A5003222708 @default.
• W2134675585 hasAuthorship W2134675585A5017899525 @default.
• W2134675585 hasAuthorship W2134675585A5022555743 @default.
• W2134675585 hasAuthorship W2134675585A5045900479 @default.
• W2134675585 hasConcept C104317684 @default.
• W2134675585 hasConcept C136834591 @default.
• W2134675585 hasConcept C148738053 @default.
• W2134675585 hasConcept C153911025 @default.
• W2134675585 hasConcept C170493617 @default.
• W2134675585 hasConcept C185592680 @default.
• W2134675585 hasConcept C201750760 @default.
• W2134675585 hasConcept C2775960820 @default.
• W2134675585 hasConcept C28328180 @default.
• W2134675585 hasConcept C55493867 @default.
• W2134675585 hasConcept C86803240 @default.
• W2134675585 hasConcept C95444343 @default.
• W2134675585 hasConceptScore W2134675585C104317684 @default.
• W2134675585 hasConceptScore W2134675585C136834591 @default.
• W2134675585 hasConceptScore W2134675585C148738053 @default.
• W2134675585 hasConceptScore W2134675585C153911025 @default.
• W2134675585 hasConceptScore W2134675585C170493617 @default.
• W2134675585 hasConceptScore W2134675585C185592680 @default.
• W2134675585 hasConceptScore W2134675585C201750760 @default.
• W2134675585 hasConceptScore W2134675585C2775960820 @default.
• W2134675585 hasConceptScore W2134675585C28328180 @default.
• W2134675585 hasConceptScore W2134675585C55493867 @default.
• W2134675585 hasConceptScore W2134675585C86803240 @default.
• W2134675585 hasConceptScore W2134675585C95444343 @default.
• W2134675585 hasIssue "35" @default.
• W2134675585 hasLocation W21346755851 @default.
• W2134675585 hasLocation W21346755852 @default.
• W2134675585 hasOpenAccess W2134675585 @default.
• W2134675585 hasPrimaryLocation W21346755851 @default.
• W2134675585 hasRelatedWork W2026748421 @default.
• W2134675585 hasRelatedWork W2033631724 @default.
• W2134675585 hasRelatedWork W2063301313 @default.
• W2134675585 hasRelatedWork W2091029514 @default.

• next