Matches in SemOpenAlex for { <https://semopenalex.org/work/W2134711605> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2134711605 endingPage "295" @default.
- W2134711605 startingPage "289" @default.
- W2134711605 abstract "Cells belonging to the malignant clone are found in the peripheral blood in myeloma patients. In order to minimise the content of tumour cells in the stem cell product it is crucial to perform stem cell harvest at a time when tumour cells in the peripheral blood are at a minimum.The aim of the study was to compare the mobilisation kinetics of normal CD34+ cells and myeloma plasma cells during mobilisation with either G-CSF alone or high-dose cyclophosphamide (HDCy) plus G-CSF.Morning blood samples were drawn each day during mobilisation from start of G-CSF or HDCy and to the end of leukapheresis, and were analysed by flow cytometry for content of CD34+ cells and myeloma plasma cells (CD38+ + CD45-). Tumour cells were also estimated by a patient-specific real-time polymerase chain reaction (PCR) method based on the 5' nuclease TaqMan technology.Flow cytometry data from 16 patients showed concomitant mobilisation of CD34+ cells and myeloma plasma cells. Seven patients were mobilised twice; first with G-CSF alone and then with HDCy plus G-CSF. There was no difference between the two mobilisation regimens regarding tumour cell mobilisation kinetics. Real-time PCR was performed in one patient and confirmed the mobilisation of tumour cells at the time when CD34+ blood cells were at a maximum.Tumour cells are mobilised to the peripheral blood at the same time as CD34+ cells in multiple myeloma patients after priming with both G-CSF alone and HDCy in combination with G-CSF." @default.
- W2134711605 created "2016-06-24" @default.
- W2134711605 creator A5050796612 @default.
- W2134711605 creator A5067441032 @default.
- W2134711605 creator A5086469926 @default.
- W2134711605 creator A5089487687 @default.
- W2134711605 date "2001-11-01" @default.
- W2134711605 modified "2023-10-15" @default.
- W2134711605 title "Mobilisation of tumour cells along with CD34<sup>+</sup> cells to peripheral blood in multiple myeloma" @default.
- W2134711605 cites W146026460 @default.
- W2134711605 cites W1591369027 @default.
- W2134711605 cites W1622280622 @default.
- W2134711605 cites W1879666912 @default.
- W2134711605 cites W1976154943 @default.
- W2134711605 cites W1976605570 @default.
- W2134711605 cites W1990099125 @default.
- W2134711605 cites W2000626804 @default.
- W2134711605 cites W2003367269 @default.
- W2134711605 cites W2010365172 @default.
- W2134711605 cites W2020751729 @default.
- W2134711605 cites W2021820418 @default.
- W2134711605 cites W2029534940 @default.
- W2134711605 cites W2043410355 @default.
- W2134711605 cites W2058471214 @default.
- W2134711605 cites W2061243005 @default.
- W2134711605 cites W2068552466 @default.
- W2134711605 cites W2074347158 @default.
- W2134711605 cites W2075052814 @default.
- W2134711605 cites W2079612806 @default.
- W2134711605 cites W2118443286 @default.
- W2134711605 cites W2271876496 @default.
- W2134711605 cites W2319749516 @default.
- W2134711605 cites W2324841806 @default.
- W2134711605 cites W2373939791 @default.
- W2134711605 cites W2418641834 @default.
- W2134711605 cites W3145716452 @default.
- W2134711605 cites W4238040389 @default.
- W2134711605 doi "https://doi.org/10.1034/j.1600-0609.2001.00504.x" @default.
- W2134711605 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11872076" @default.
- W2134711605 hasPublicationYear "2001" @default.
- W2134711605 type Work @default.
- W2134711605 sameAs 2134711605 @default.
- W2134711605 citedByCount "11" @default.
- W2134711605 countsByYear W21347116052016 @default.
- W2134711605 crossrefType "journal-article" @default.
- W2134711605 hasAuthorship W2134711605A5050796612 @default.
- W2134711605 hasAuthorship W2134711605A5067441032 @default.
- W2134711605 hasAuthorship W2134711605A5086469926 @default.
- W2134711605 hasAuthorship W2134711605A5089487687 @default.
- W2134711605 hasConcept C10205521 @default.
- W2134711605 hasConcept C159912055 @default.
- W2134711605 hasConcept C203014093 @default.
- W2134711605 hasConcept C2776364478 @default.
- W2134711605 hasConcept C2777371436 @default.
- W2134711605 hasConcept C28328180 @default.
- W2134711605 hasConcept C502942594 @default.
- W2134711605 hasConcept C54355233 @default.
- W2134711605 hasConcept C552990157 @default.
- W2134711605 hasConcept C553184892 @default.
- W2134711605 hasConcept C71924100 @default.
- W2134711605 hasConcept C81089528 @default.
- W2134711605 hasConcept C86803240 @default.
- W2134711605 hasConceptScore W2134711605C10205521 @default.
- W2134711605 hasConceptScore W2134711605C159912055 @default.
- W2134711605 hasConceptScore W2134711605C203014093 @default.
- W2134711605 hasConceptScore W2134711605C2776364478 @default.
- W2134711605 hasConceptScore W2134711605C2777371436 @default.
- W2134711605 hasConceptScore W2134711605C28328180 @default.
- W2134711605 hasConceptScore W2134711605C502942594 @default.
- W2134711605 hasConceptScore W2134711605C54355233 @default.
- W2134711605 hasConceptScore W2134711605C552990157 @default.
- W2134711605 hasConceptScore W2134711605C553184892 @default.
- W2134711605 hasConceptScore W2134711605C71924100 @default.
- W2134711605 hasConceptScore W2134711605C81089528 @default.
- W2134711605 hasConceptScore W2134711605C86803240 @default.
- W2134711605 hasIssue "5-6" @default.
- W2134711605 hasLocation W21347116051 @default.
- W2134711605 hasLocation W21347116052 @default.
- W2134711605 hasOpenAccess W2134711605 @default.
- W2134711605 hasPrimaryLocation W21347116051 @default.
- W2134711605 hasRelatedWork W2027531937 @default.
- W2134711605 hasRelatedWork W2035637894 @default.
- W2134711605 hasRelatedWork W2078419371 @default.
- W2134711605 hasRelatedWork W2092890208 @default.
- W2134711605 hasRelatedWork W2156425432 @default.
- W2134711605 hasRelatedWork W2356698346 @default.
- W2134711605 hasRelatedWork W2384925166 @default.
- W2134711605 hasRelatedWork W2389117465 @default.
- W2134711605 hasRelatedWork W2410530111 @default.
- W2134711605 hasRelatedWork W2977283648 @default.
- W2134711605 hasVolume "67" @default.
- W2134711605 isParatext "false" @default.
- W2134711605 isRetracted "false" @default.
- W2134711605 magId "2134711605" @default.
- W2134711605 workType "article" @default.