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• W2134732904 abstract "The hypothesis of this study was that 17β-estradiol (estradiol) stimulates turkey skeletal muscle growth by influencing myogenic satellite cell proliferation, differentiation, and the gene expression of selected proteins important in regulating growth and development. Increasing levels of estradiol were administered in basal medium containing additional nutrients. Female-derived pectoralis major (PM) satellite cell proliferation was stimulated by estradiol at a level of 10− 9 M following 4 days of treatment. Male PM and biceps femoris (BF) satellite cell proliferation was increased at 10− 12 M estradiol. Turkey embryonic myoblast proliferation, however, decreased with 10− 9 M and 10− 5 M estradiol following 3 days under these conditions. Estradiol had no effect on the differentiation of any of the 4 groups of cells. Likewise, glypican-1 expression was unaffected by estradiol treatment. MyoD expression decreased in male PM but not BF cells. MyoD expression in female PM cells and embryonic myoblasts were also unaffected by estradiol administration. Estradiol decreased myogenin expression in male satellite cells, but had no effect on female cells. There was a slight decrease in myogenin expression in embryonic myoblasts. The results demonstrate a direct effect of estradiol on avian satellite cell proliferation independent of glypican-1, and decreased expression of MyoD and myogenin in some myogenic cells, coinciding with increased cellular proliferation." @default.
• W2134732904 created "2016-06-24" @default.
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• W2134732904 date "2013-04-01" @default.
• W2134732904 modified "2023-09-28" @default.
• W2134732904 title "Effects of 17β-estradiol on turkey myogenic satellite cell proliferation, differentiation, and expression of glypican-1, MyoD and myogenin" @default.
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• W2134732904 doi "https://doi.org/10.1016/j.cbpa.2013.01.001" @default.
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