FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2134740709> ?p ?o ?g. }

• W2134740709 endingPage "689" @default.
• W2134740709 startingPage "683" @default.
• W2134740709 abstract "ABSTRACT Previous prospective cohort studies have shown that serum levels of sex steroids and sex hormone‐binding globulin (SHBG) associate with nonvertebral fracture risk in men. The predictive value of sex hormones and SHBG for vertebral fracture risk specifically is, however, less studied. Elderly men (aged ≥65 years) from Sweden and Hong Kong participating in the Osteoporotic Fractures in Men (MrOS) study had baseline estradiol and testosterone analyzed by gas chromatography–mass spectrometry (GC‐MS) and SHBG by immunoradiometric assay (IRMA). Incident clinical vertebral fractures ( n = 242 cases) were evaluated in 4324 men during an average follow‐up of 9.1 years. In a subsample of these men ( n = 2256), spine X‐rays were obtained at baseline and after an average follow‐up of 4.3 years to identify incident radiographic vertebral fractures ( n = 157 cases). The likelihood of incident clinical and radiographic vertebral fractures was estimated by Cox proportional hazards models and logistic regression models, respectively. Neither serum estradiol (hazard ratio [HR] per SD increase = 0.93, 95% confidence interval [CI] 0.80–1.08) nor testosterone (1.05, 0.91–1.21) predicted incident clinical vertebral fractures in age‐adjusted models in the combined data set. High serum SHBG, however, associated with increased clinical vertebral fracture risk (1.24, 1.12–1.37). This association remained significant after further adjustment for FRAX with or without bone mineral density (BMD). SHBG also associated with increased incident radiographic vertebral fracture risk (combined data set; odds ratio [OR] per SD increase = 1.23, 95% CI 1.05–1.44). This association remained significant after adjustment for FRAX with or without BMD. In conclusion, high SHBG predicts incident clinical and radiographic vertebral fractures in elderly men and adds moderate information beyond FRAX with BMD for vertebral fracture risk prediction. © 2015 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals, Inc. on behalf of American Society for Bone and Mineral Research." @default.
• W2134740709 created "2016-06-24" @default.
• W2134740709 creator A5015033158 @default.
• W2134740709 creator A5037824580 @default.
• W2134740709 creator A5047826903 @default.
• W2134740709 creator A5053331431 @default.
• W2134740709 creator A5062528819 @default.
• W2134740709 creator A5066637374 @default.
• W2134740709 creator A5074328914 @default.
• W2134740709 creator A5079254917 @default.
• W2134740709 creator A5081677893 @default.
• W2134740709 creator A5082508582 @default.
• W2134740709 creator A5083203170 @default.
• W2134740709 creator A5091032474 @default.
• W2134740709 date "2016-01-20" @default.
• W2134740709 modified "2023-09-27" @default.
• W2134740709 title "High Serum SHBG Predicts Incident Vertebral Fractures in Elderly Men" @default.
• W2134740709 cites W1513674708 @default.
• W2134740709 cites W1976746229 @default.
• W2134740709 cites W1982655803 @default.
• W2134740709 cites W1984796312 @default.
• W2134740709 cites W1992140239 @default.
• W2134740709 cites W1993587682 @default.
• W2134740709 cites W2000337048 @default.
• W2134740709 cites W2002354348 @default.
• W2134740709 cites W2003710746 @default.
• W2134740709 cites W2032575860 @default.
• W2134740709 cites W2044178924 @default.
• W2134740709 cites W2053235351 @default.
• W2134740709 cites W2057680272 @default.
• W2134740709 cites W2070698531 @default.
• W2134740709 cites W2093498393 @default.
• W2134740709 cites W2096540379 @default.
• W2134740709 cites W2106105679 @default.
• W2134740709 cites W2111674612 @default.
• W2134740709 cites W2112316706 @default.
• W2134740709 cites W2114269632 @default.
• W2134740709 cites W2130515633 @default.
• W2134740709 cites W2136914247 @default.
• W2134740709 cites W2139796029 @default.
• W2134740709 cites W2140313736 @default.
• W2134740709 cites W2155000335 @default.
• W2134740709 cites W2162115101 @default.
• W2134740709 cites W2163690987 @default.
• W2134740709 cites W2328176404 @default.
• W2134740709 cites W373968353 @default.
• W2134740709 cites W4232718592 @default.
• W2134740709 cites W4254556107 @default.
• W2134740709 cites W4378638159 @default.
• W2134740709 doi "https://doi.org/10.1002/jbmr.2718" @default.
• W2134740709 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4832265" @default.
• W2134740709 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26391196" @default.
• W2134740709 hasPublicationYear "2016" @default.
• W2134740709 type Work @default.
• W2134740709 sameAs 2134740709 @default.
• W2134740709 citedByCount "34" @default.
• W2134740709 countsByYear W21347407092016 @default.
• W2134740709 countsByYear W21347407092017 @default.
• W2134740709 countsByYear W21347407092018 @default.
• W2134740709 countsByYear W21347407092019 @default.
• W2134740709 countsByYear W21347407092020 @default.
• W2134740709 countsByYear W21347407092021 @default.
• W2134740709 countsByYear W21347407092022 @default.
• W2134740709 countsByYear W21347407092023 @default.
• W2134740709 crossrefType "journal-article" @default.
• W2134740709 hasAuthorship W2134740709A5015033158 @default.
• W2134740709 hasAuthorship W2134740709A5037824580 @default.
• W2134740709 hasAuthorship W2134740709A5047826903 @default.
• W2134740709 hasAuthorship W2134740709A5053331431 @default.
• W2134740709 hasAuthorship W2134740709A5062528819 @default.
• W2134740709 hasAuthorship W2134740709A5066637374 @default.
• W2134740709 hasAuthorship W2134740709A5074328914 @default.
• W2134740709 hasAuthorship W2134740709A5079254917 @default.
• W2134740709 hasAuthorship W2134740709A5081677893 @default.
• W2134740709 hasAuthorship W2134740709A5082508582 @default.
• W2134740709 hasAuthorship W2134740709A5083203170 @default.
• W2134740709 hasAuthorship W2134740709A5091032474 @default.
• W2134740709 hasBestOaLocation W21347407091 @default.
• W2134740709 hasConcept C126322002 @default.
• W2134740709 hasConcept C134018914 @default.
• W2134740709 hasConcept C151956035 @default.
• W2134740709 hasConcept C156957248 @default.
• W2134740709 hasConcept C188816634 @default.
• W2134740709 hasConcept C207103383 @default.
• W2134740709 hasConcept C2776541429 @default.
• W2134740709 hasConcept C2776886416 @default.
• W2134740709 hasConcept C2777525943 @default.
• W2134740709 hasConcept C2777911890 @default.
• W2134740709 hasConcept C2779279991 @default.
• W2134740709 hasConcept C2779329777 @default.
• W2134740709 hasConcept C2994343686 @default.
• W2134740709 hasConcept C30092816 @default.
• W2134740709 hasConcept C44249647 @default.
• W2134740709 hasConcept C50382708 @default.
• W2134740709 hasConcept C71315377 @default.
• W2134740709 hasConcept C71924100 @default.
• W2134740709 hasConceptScore W2134740709C126322002 @default.
• W2134740709 hasConceptScore W2134740709C134018914 @default.

• next