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• W2134764336 abstract "We report the isolation of two different homeo box genes, HB3 and HB4, from the Hawaiian sea urchin Tripneustes gratilla . DNA sequencing revealed a definitive Antennapedia(Antp) class homeo box in each gene. Southern transfer hybridizations showed the genes to be single-copy. A 5.7-kb transcript of the HB3 gene was found in ovary, testis, small intestine and gastrula poly(A) + RNA. The HB4 gene produces three transcripts. A 3.7-kb and a 4.4-kb transcript are expressed during embryogenesis. A 3.5-kb transcript appears in each of the adult tissues studied. The HB4 gene appears to be the sea urchin cognate of the Drosophila infrabdominal-7 (iab-7) gene, the mouse Hox 1.7 and Hox 3.2 genes and the Xenopus XlHbox 6 gene. An examination of Antp class homeo box genes in deuterostomes indicates that a chromosomal duplication has taken place in the evolutionary line leading to the vertebrates after the divergence of the echinoderms. Thus, the sea urchin represents the primitive condition." @default.
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• W2134764336 date "1988-01-01" @default.
• W2134764336 modified "2023-09-26" @default.
• W2134764336 title "Stage- and tissue-specific expression of two homeo box genes in sea urchin embryos and adults" @default.
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• W2134764336 doi "https://doi.org/10.1093/nar/16.24.11543" @default.
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