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• W2134767616 endingPage "4294" @default.
• W2134767616 startingPage "4283" @default.
• W2134767616 abstract "Sister chromatid recombination (SCR) is a potentially error-free pathway for the repair of DNA lesions associated with replication and is thought to be important for suppressing genomic instability. The mechanisms regulating the initiation and termination of SCR in mammalian cells are poorly understood. Previous work has implicated all the Rad51 paralogs in the initiation of gene conversion and the Rad51C/XRCC3 complex in its termination. Here, we show that hamster cells deficient in the Rad51 paralog XRCC2, a component of the Rad51B/Rad51C/Rad51D/XRCC2 complex, reveal a bias in favor of long-tract gene conversion (LTGC) during SCR. This defect is corrected by expression of wild-type XRCC2 and also by XRCC2 mutants defective in ATP binding and hydrolysis. In contrast, XRCC3-mediated homologous recombination and suppression of LTGC are dependent on ATP binding and hydrolysis. These results reveal an unexpectedly general role for Rad51 paralogs in the control of the termination of gene conversion between sister chromatids." @default.
• W2134767616 created "2016-06-24" @default.
• W2134767616 creator A5018857935 @default.
• W2134767616 creator A5026651627 @default.
• W2134767616 creator A5049222210 @default.
• W2134767616 creator A5059044712 @default.
• W2134767616 creator A5084834968 @default.
• W2134767616 date "2009-08-01" @default.
• W2134767616 modified "2023-09-27" @default.
• W2134767616 title "XRCC2 and XRCC3 Regulate the Balance between Short- and Long-Tract Gene Conversions between Sister Chromatids" @default.
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• W2134767616 cites W1512321076 @default.
• W2134767616 cites W1540750107 @default.
• W2134767616 cites W1562677361 @default.
• W2134767616 cites W1570361288 @default.
• W2134767616 cites W1965531809 @default.
• W2134767616 cites W1968469516 @default.
• W2134767616 cites W1970136416 @default.
• W2134767616 cites W1971018769 @default.
• W2134767616 cites W1973711554 @default.
• W2134767616 cites W1974062259 @default.
• W2134767616 cites W1976430502 @default.
• W2134767616 cites W1979385111 @default.
• W2134767616 cites W1980194687 @default.
• W2134767616 cites W1989136612 @default.
• W2134767616 cites W1991984898 @default.
• W2134767616 cites W1992183932 @default.
• W2134767616 cites W2002131406 @default.
• W2134767616 cites W2003755228 @default.
• W2134767616 cites W2004360438 @default.
• W2134767616 cites W2007663015 @default.
• W2134767616 cites W2010711320 @default.
• W2134767616 cites W2011912935 @default.
• W2134767616 cites W2012838063 @default.
• W2134767616 cites W2018520585 @default.
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• W2134767616 cites W2028138760 @default.
• W2134767616 cites W2030639168 @default.
• W2134767616 cites W2032809709 @default.
• W2134767616 cites W2041389422 @default.
• W2134767616 cites W2041929141 @default.
• W2134767616 cites W2047288052 @default.
• W2134767616 cites W2047504175 @default.
• W2134767616 cites W2050345170 @default.
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• W2134767616 cites W2062072040 @default.
• W2134767616 cites W2064728219 @default.
• W2134767616 cites W2066527798 @default.
• W2134767616 cites W2066969492 @default.
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• W2134767616 doi "https://doi.org/10.1128/mcb.01406-08" @default.
• W2134767616 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2715807" @default.
• W2134767616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19470754" @default.
• W2134767616 hasPublicationYear "2009" @default.
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