Matches in SemOpenAlex for { <https://semopenalex.org/work/W2134769436> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2134769436 endingPage "38" @default.
- W2134769436 startingPage "34" @default.
- W2134769436 abstract "Delporte C, Miller G, Kagami H, Lillibridge CD, O'Connell BC, Atkinson JC, Baum BJ: Safety of salivary gland-administered replication-deficient recombinant adenovirus in rats. J Oral Pathol Med 1998; 27: 34–8. © Munksgaard, 1998. We have examined the safety of a replication-deficient recombinant adenovirus administered at a single, high dose intraductally to rat submandibular glands or systemically via the femoral vein. The virus used directed the synthesis of human aquaporin-1, a water channel protein, and is termed AdhAQPl. Comparisons were made 1 and 9 days post-infection with animals administered either a similar virus encoding no transgene or the viral suspension buffer. Animals were specifically not given anti-inflammatory drugs to impede the well-known immunopathologic response to recombinant adenoviral administration. Serum chemistries and hematological parameters were monitored. Rats were subjected to complete gross necropsy and selected tissues were evaluated by histopathology. Most clinical chemistry and hematology values were within normal ranges; however, evidence of inflammation (e.g., elevated lactic dehydrogenase, total leukocyte count) was seen. Gross pathology was normal, as was histopathology, excepting rare focal areas of necrosis. The results show that intrasalivary gland or intravenous AdhAQPl administration leads to low levels of toxicity in rats." @default.
- W2134769436 created "2016-06-24" @default.
- W2134769436 creator A5000020735 @default.
- W2134769436 creator A5013466490 @default.
- W2134769436 creator A5020417873 @default.
- W2134769436 creator A5059509627 @default.
- W2134769436 creator A5064451543 @default.
- W2134769436 creator A5068692055 @default.
- W2134769436 creator A5083435709 @default.
- W2134769436 date "2007-07-13" @default.
- W2134769436 modified "2023-09-26" @default.
- W2134769436 title "Safety of salivary gland-administered replication-deficient recombinant adenovirus in rats" @default.
- W2134769436 cites W1981702861 @default.
- W2134769436 cites W1989669523 @default.
- W2134769436 cites W1999157369 @default.
- W2134769436 cites W2011213447 @default.
- W2134769436 cites W2023329018 @default.
- W2134769436 cites W2048873879 @default.
- W2134769436 cites W2065244674 @default.
- W2134769436 cites W2067379696 @default.
- W2134769436 cites W2075350162 @default.
- W2134769436 cites W2079209506 @default.
- W2134769436 cites W2085583466 @default.
- W2134769436 cites W2090983403 @default.
- W2134769436 cites W2093082335 @default.
- W2134769436 cites W2131306390 @default.
- W2134769436 doi "https://doi.org/10.1111/j.1600-0714.1998.tb02088.x" @default.
- W2134769436 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9466733" @default.
- W2134769436 hasPublicationYear "2007" @default.
- W2134769436 type Work @default.
- W2134769436 sameAs 2134769436 @default.
- W2134769436 citedByCount "14" @default.
- W2134769436 countsByYear W21347694362014 @default.
- W2134769436 countsByYear W21347694362015 @default.
- W2134769436 countsByYear W21347694362016 @default.
- W2134769436 countsByYear W21347694362021 @default.
- W2134769436 crossrefType "journal-article" @default.
- W2134769436 hasAuthorship W2134769436A5000020735 @default.
- W2134769436 hasAuthorship W2134769436A5013466490 @default.
- W2134769436 hasAuthorship W2134769436A5020417873 @default.
- W2134769436 hasAuthorship W2134769436A5059509627 @default.
- W2134769436 hasAuthorship W2134769436A5064451543 @default.
- W2134769436 hasAuthorship W2134769436A5068692055 @default.
- W2134769436 hasAuthorship W2134769436A5083435709 @default.
- W2134769436 hasConcept C104317684 @default.
- W2134769436 hasConcept C126322002 @default.
- W2134769436 hasConcept C142724271 @default.
- W2134769436 hasConcept C194409129 @default.
- W2134769436 hasConcept C203014093 @default.
- W2134769436 hasConcept C2522874641 @default.
- W2134769436 hasConcept C2776954459 @default.
- W2134769436 hasConcept C2778937882 @default.
- W2134769436 hasConcept C39060996 @default.
- W2134769436 hasConcept C40767141 @default.
- W2134769436 hasConcept C544855455 @default.
- W2134769436 hasConcept C55493867 @default.
- W2134769436 hasConcept C71924100 @default.
- W2134769436 hasConcept C86803240 @default.
- W2134769436 hasConceptScore W2134769436C104317684 @default.
- W2134769436 hasConceptScore W2134769436C126322002 @default.
- W2134769436 hasConceptScore W2134769436C142724271 @default.
- W2134769436 hasConceptScore W2134769436C194409129 @default.
- W2134769436 hasConceptScore W2134769436C203014093 @default.
- W2134769436 hasConceptScore W2134769436C2522874641 @default.
- W2134769436 hasConceptScore W2134769436C2776954459 @default.
- W2134769436 hasConceptScore W2134769436C2778937882 @default.
- W2134769436 hasConceptScore W2134769436C39060996 @default.
- W2134769436 hasConceptScore W2134769436C40767141 @default.
- W2134769436 hasConceptScore W2134769436C544855455 @default.
- W2134769436 hasConceptScore W2134769436C55493867 @default.
- W2134769436 hasConceptScore W2134769436C71924100 @default.
- W2134769436 hasConceptScore W2134769436C86803240 @default.
- W2134769436 hasIssue "1" @default.
- W2134769436 hasLocation W21347694361 @default.
- W2134769436 hasLocation W21347694362 @default.
- W2134769436 hasOpenAccess W2134769436 @default.
- W2134769436 hasPrimaryLocation W21347694361 @default.
- W2134769436 hasRelatedWork W1966003144 @default.
- W2134769436 hasRelatedWork W2024334721 @default.
- W2134769436 hasRelatedWork W2088538321 @default.
- W2134769436 hasRelatedWork W2142885368 @default.
- W2134769436 hasRelatedWork W2144111621 @default.
- W2134769436 hasRelatedWork W2232603015 @default.
- W2134769436 hasRelatedWork W2327903412 @default.
- W2134769436 hasRelatedWork W2502200583 @default.
- W2134769436 hasRelatedWork W3035174909 @default.
- W2134769436 hasRelatedWork W3116393210 @default.
- W2134769436 hasVolume "27" @default.
- W2134769436 isParatext "false" @default.
- W2134769436 isRetracted "false" @default.
- W2134769436 magId "2134769436" @default.
- W2134769436 workType "article" @default.