FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2134795478> ?p ?o ?g. }

• W2134795478 endingPage "37" @default.
• W2134795478 startingPage "37" @default.
• W2134795478 abstract "Technological advances in molecular and in silico research have enabled significant progress towards personalized transplantation medicine. It is now possible to conduct comprehensive biomarker development studies of transplant organ pathologies, correlating genomic, transcriptomic and proteomic information from donor and recipient with clinical and histological phenotypes. Translation of these advances to the clinical setting will allow assessment of an individual patient's risk of allograft damage or accommodation. Transplantation biomarkers are needed for active monitoring of immunosuppression, to reduce patient morbidity, and to improve long-term allograft function and life expectancy. Here, we highlight recent pre- and post-transplantation biomarkers of acute and chronic allograft damage or adaptation, focusing on peripheral blood-based methodologies for non-invasive application. We then critically discuss current findings with respect to their future application in routine clinical transplantation medicine. Complement-system-associated SNPs present potential biomarkers that may be used to indicate the baseline risk for allograft damage prior to transplantation. The detection of antibodies against novel, non-HLA, MICA antigens, and the expression of cytokine genes and proteins and cytotoxicity-related genes have been correlated with allograft damage and are potential post-transplantation biomarkers indicating allograft damage at the molecular level, although these do not have clinical relevance yet. Several multi-gene expression-based biomarker panels have been identified that accurately predicted graft accommodation in liver transplant recipients and may be developed into a predictive biomarker assay." @default.
• W2134795478 created "2016-06-24" @default.
• W2134795478 creator A5041269832 @default.
• W2134795478 creator A5076606355 @default.
• W2134795478 creator A5078309982 @default.
• W2134795478 creator A5083763463 @default.
• W2134795478 date "2011-01-01" @default.
• W2134795478 modified "2023-10-16" @default.
• W2134795478 title "Biomarkers in solid organ transplantation: establishing personalized transplantation medicine" @default.
• W2134795478 cites W1964141277 @default.
• W2134795478 cites W1964405385 @default.
• W2134795478 cites W1965971863 @default.
• W2134795478 cites W1973588103 @default.
• W2134795478 cites W1974321626 @default.
• W2134795478 cites W1975129554 @default.
• W2134795478 cites W1975667891 @default.
• W2134795478 cites W1976103632 @default.
• W2134795478 cites W1977083976 @default.
• W2134795478 cites W1978206249 @default.
• W2134795478 cites W1986974300 @default.
• W2134795478 cites W1990440809 @default.
• W2134795478 cites W1992563074 @default.
• W2134795478 cites W1993577458 @default.
• W2134795478 cites W1993707861 @default.
• W2134795478 cites W1993992417 @default.
• W2134795478 cites W1994085514 @default.
• W2134795478 cites W1995653774 @default.
• W2134795478 cites W1998271677 @default.
• W2134795478 cites W1998331046 @default.
• W2134795478 cites W1998501202 @default.
• W2134795478 cites W1998668551 @default.
• W2134795478 cites W1999419565 @default.
• W2134795478 cites W2001121246 @default.
• W2134795478 cites W2001775960 @default.
• W2134795478 cites W2004882261 @default.
• W2134795478 cites W2005981959 @default.
• W2134795478 cites W2006453595 @default.
• W2134795478 cites W2007241835 @default.
• W2134795478 cites W2008161741 @default.
• W2134795478 cites W2009705033 @default.
• W2134795478 cites W2010637767 @default.
• W2134795478 cites W2010715886 @default.
• W2134795478 cites W2011810052 @default.
• W2134795478 cites W2014200075 @default.
• W2134795478 cites W2014955040 @default.
• W2134795478 cites W2016980966 @default.
• W2134795478 cites W2017250121 @default.
• W2134795478 cites W2018137555 @default.
• W2134795478 cites W2019671943 @default.
• W2134795478 cites W2021560851 @default.
• W2134795478 cites W2025048568 @default.
• W2134795478 cites W2028426093 @default.
• W2134795478 cites W2039499065 @default.
• W2134795478 cites W2040553735 @default.
• W2134795478 cites W2041199873 @default.
• W2134795478 cites W2042060413 @default.
• W2134795478 cites W2046965152 @default.
• W2134795478 cites W2050281416 @default.
• W2134795478 cites W2056933088 @default.
• W2134795478 cites W2065318289 @default.
• W2134795478 cites W2073793989 @default.
• W2134795478 cites W2078745327 @default.
• W2134795478 cites W2082253471 @default.
• W2134795478 cites W2086007558 @default.
• W2134795478 cites W2088299419 @default.
• W2134795478 cites W2090006740 @default.
• W2134795478 cites W2090184061 @default.
• W2134795478 cites W2094446254 @default.
• W2134795478 cites W2096037842 @default.
• W2134795478 cites W2096269949 @default.
• W2134795478 cites W2099801548 @default.
• W2134795478 cites W2103724228 @default.
• W2134795478 cites W2115083462 @default.
• W2134795478 cites W2116493322 @default.
• W2134795478 cites W2116642156 @default.
• W2134795478 cites W2118674671 @default.
• W2134795478 cites W2118816312 @default.
• W2134795478 cites W2130193496 @default.
• W2134795478 cites W2130264854 @default.
• W2134795478 cites W2130820062 @default.
• W2134795478 cites W2133571578 @default.
• W2134795478 cites W2137442990 @default.
• W2134795478 cites W2141478377 @default.
• W2134795478 cites W2145117163 @default.
• W2134795478 cites W2145646761 @default.
• W2134795478 cites W2146532256 @default.
• W2134795478 cites W2148001303 @default.
• W2134795478 cites W2155388222 @default.
• W2134795478 cites W2165349573 @default.
• W2134795478 cites W2165596518 @default.
• W2134795478 cites W2320300118 @default.
• W2134795478 cites W2337008570 @default.
• W2134795478 cites W2913527798 @default.
• W2134795478 doi "https://doi.org/10.1186/gm253" @default.
• W2134795478 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3218811" @default.
• W2134795478 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21658299" @default.
• W2134795478 hasPublicationYear "2011" @default.
• W2134795478 type Work @default.

• next