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- W2134827116 abstract "Empirical experimental pain research suggests that women show greater pain responsivity than men. In children, this sex difference has not been as clearly demonstrated, perhaps due to developmental confounds associated with puberty. We sought to understand how gender (sex), age, and puberty relate to experimental pain in children (aged 8 to 18 years). The sample included 234 healthy children (mean age 12.7, SD 2.9): 109 in early puberty (54 female, 55 male) and 125 in late puberty (63 female, 62 male). Participants completed cold, heat, and pressure pain tasks and provided behavioral measures of pain tolerance and self-reports of pain intensity and distress, with all three measures comprising the dependent variables (DVs). Self-reporting of pubertal stage was made by Tanner pictographs. Age, sex, and puberty (dichotomized early/late) along with sex-by-age and sex-by-puberty interaction terms were entered as independent variables in general linear models to predict each of the DVs. Results indicate tolerance to the pressure task was higher in late puberty and in males than in early puberty and females, respectively. For the heat task, tolerance was positively related with age, but further predicted by the sex-by-age interaction term (tolerance in males increased at a greater rate than in females with increasing age). Late puberty was related to higher cold task tolerance, and a sex-by-age interaction indicated male tolerance increased with age, while female tolerance decreased. Age and pain intensity self-ratings were positively related for the heat and pressure tasks, as were age and pain distress for heat. These results provide some support for diverging developmental trajectories in pain tolerance for boys and girls. Limited evidence also suggests that puberty, after accounting for age, impacts pain responsivity, although the high age/puberty correlation makes teasing these two apart difficult. Data on hormonal and other factors may help explain our findings." @default.
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- W2134827116 date "2005-03-01" @default.
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- W2134827116 title "Gender, age, and puberty in children’s experimental pain" @default.
- W2134827116 doi "https://doi.org/10.1016/j.jpain.2005.01.005" @default.
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