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• W2134839941 startingPage "R303" @default.
• W2134839941 abstract "Human chromosome 7 is arguably amongst the most comprehensively characterized segments of the human genome. By microscopic examination, it belongs to the medium-sized group C submetacentric class, and historical studies involving chromosome-length measurements estimated that it accounts for ∼5.3% of the human genome (or 160 Mb). Early successes in molecular genetics led to the identification of some of its biomedically important genes, including the T-cell receptor and homeobox families as well as the erythropoietin and cystic fibrosis genes. The Human Genome Project brought chromosome 7-specific and genome-wide initiatives, generating a wealth of genomic resources that have revealed the presence of over 350 disease-associated genes. Two distinct assemblies of the chromosome 7 sequence have been generated—one based largely on mapped large-insert clones and the other based on an integrated whole-genome shotgun sequencing strategy. These two sequences are mainly identical (<1% difference), and both estimate the unit length of chromosome 7 to be just over 158 Mb, remarkably similar to the originally predicted size. Systematic annotation efforts have anchored to the sequence, amongst many features, over 900 known genes and some 1000 other gene structures, as well as over 650 chromosomal breakpoints identified in patients with characterized phenotypic differences. Chromosome 7 has also been shown to contain the highest content of intra-autosomal segmental duplications in the human genome. The orthologous regions of roughly 22 Mb of chromosome 7 are currently being sequenced in multiple other vertebrate species. Examining these comparative sequence data, in conjunction with the other accumulating genomic information about these regions and the rest of the chromosome, should provide a model for the next generation of structural and functional analyses of the human genome." @default.
• W2134839941 created "2016-06-24" @default.
• W2134839941 creator A5031230494 @default.
• W2134839941 creator A5049296994 @default.
• W2134839941 date "2004-10-01" @default.
• W2134839941 modified "2023-09-23" @default.
• W2134839941 title "Human chromosome 7 circa 2004: a model for structural and functional studies of the human genome" @default.
• W2134839941 cites W1493823666 @default.
• W2134839941 cites W1502331465 @default.
• W2134839941 cites W1504525216 @default.
• W2134839941 cites W15453418 @default.
• W2134839941 cites W1551014578 @default.
• W2134839941 cites W1560970439 @default.
• W2134839941 cites W1572165205 @default.
• W2134839941 cites W1588409425 @default.
• W2134839941 cites W1601595149 @default.
• W2134839941 cites W1608253138 @default.
• W2134839941 cites W1608709490 @default.
• W2134839941 cites W1686085663 @default.
• W2134839941 cites W1723358241 @default.
• W2134839941 cites W1752843106 @default.
• W2134839941 cites W1923579966 @default.
• W2134839941 cites W1965007620 @default.
• W2134839941 cites W1965313969 @default.
• W2134839941 cites W1966435498 @default.
• W2134839941 cites W1967054494 @default.
• W2134839941 cites W1968350650 @default.
• W2134839941 cites W1969697265 @default.
• W2134839941 cites W1971514835 @default.
• W2134839941 cites W1971646616 @default.
• W2134839941 cites W1972113189 @default.
• W2134839941 cites W1974353375 @default.
• W2134839941 cites W1979949441 @default.
• W2134839941 cites W1979984261 @default.
• W2134839941 cites W1980255502 @default.
• W2134839941 cites W1981147791 @default.
• W2134839941 cites W1984195830 @default.
• W2134839941 cites W1984222668 @default.
• W2134839941 cites W1987191916 @default.
• W2134839941 cites W1988322592 @default.
• W2134839941 cites W1992752077 @default.
• W2134839941 cites W1992989994 @default.
• W2134839941 cites W1993056927 @default.
• W2134839941 cites W1999389174 @default.
• W2134839941 cites W2005149292 @default.
• W2134839941 cites W2006455155 @default.
• W2134839941 cites W2006698454 @default.
• W2134839941 cites W2007192246 @default.
• W2134839941 cites W2008249067 @default.
• W2134839941 cites W2009692755 @default.
• W2134839941 cites W2014364643 @default.
• W2134839941 cites W2016899885 @default.
• W2134839941 cites W2019439252 @default.
• W2134839941 cites W2019573100 @default.
• W2134839941 cites W2019996957 @default.
• W2134839941 cites W2021608281 @default.
• W2134839941 cites W202267581 @default.
• W2134839941 cites W2023471002 @default.
• W2134839941 cites W2030423815 @default.
• W2134839941 cites W2030973831 @default.
• W2134839941 cites W2031328908 @default.
• W2134839941 cites W2031900111 @default.
• W2134839941 cites W2035037356 @default.
• W2134839941 cites W2037272998 @default.
• W2134839941 cites W2039599894 @default.
• W2134839941 cites W2040724884 @default.
• W2134839941 cites W2041112284 @default.
• W2134839941 cites W2043609644 @default.
• W2134839941 cites W2044151942 @default.
• W2134839941 cites W2045040686 @default.
• W2134839941 cites W2045304058 @default.
• W2134839941 cites W2047038307 @default.
• W2134839941 cites W2054852715 @default.
• W2134839941 cites W2055628432 @default.
• W2134839941 cites W2058221210 @default.
• W2134839941 cites W2066381476 @default.
• W2134839941 cites W2067858813 @default.
• W2134839941 cites W2067984601 @default.
• W2134839941 cites W2070476377 @default.
• W2134839941 cites W2071092346 @default.
• W2134839941 cites W2072840658 @default.
• W2134839941 cites W2074106198 @default.
• W2134839941 cites W2075186587 @default.
• W2134839941 cites W2080782322 @default.
• W2134839941 cites W2084430205 @default.
• W2134839941 cites W2086078269 @default.
• W2134839941 cites W2088858763 @default.
• W2134839941 cites W2090647665 @default.
• W2134839941 cites W2098001104 @default.
• W2134839941 cites W2098798436 @default.
• W2134839941 cites W2100990361 @default.
• W2134839941 cites W2101845540 @default.
• W2134839941 cites W2106730339 @default.
• W2134839941 cites W2107934935 @default.
• W2134839941 cites W2108066473 @default.
• W2134839941 cites W2108742137 @default.
• W2134839941 cites W2114169525 @default.
• W2134839941 cites W2115261027 @default.

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