Matches in SemOpenAlex for { <https://semopenalex.org/work/W2134926481> ?p ?o ?g. }
- W2134926481 endingPage "735" @default.
- W2134926481 startingPage "723" @default.
- W2134926481 abstract "The complex protein capsids of many viruses exhibit dramatic reorganizations at critical stages in their life-cycle. Here, time-resolved solution X-ray scattering was used to study a dynamic, large-scale conformational maturation of the 420 subunit, 13 MDa, icosahedrally symmetric HK97 bacteriophage capsid. Isoscattering points in the time-resolved scattering patterns and singular value decomposition revealed that the expansion occurs as a cooperative, two-state reaction. The analysis demonstrates that the population shift from Prohead-II to Expansion Intermediate I, EI-I (60 A larger than Prohead-II) occurs in minutes, but does not reveal the time required for individual transitions that occur stochastically. Any intermediate forms that may be traversed during this conversion are unstable and do not constitute an appreciable population of the ensemble of particles. In an energetic landscape view, particles must undergo an energy barrier-crossing event in order to successfully convert from Prohead-II to EI-I. This implies that the particles hop over the energy barrier stochastically as they individually attain an expansion-active state. Interestingly, systematic deviations from single-exponential kinetics were observed for the population shift. This may indicate that in undergoing the irreversible conversion from Prohead-II to EI-I, particles are subject to a complex energy landscape that links the initial and final particle forms." @default.
- W2134926481 created "2016-06-24" @default.
- W2134926481 creator A5038647247 @default.
- W2134926481 creator A5049971572 @default.
- W2134926481 creator A5065689974 @default.
- W2134926481 creator A5072521798 @default.
- W2134926481 creator A5078724396 @default.
- W2134926481 date "2005-09-01" @default.
- W2134926481 modified "2023-09-25" @default.
- W2134926481 title "Cooperative Reorganization of a 420 Subunit Virus Capsid" @default.
- W2134926481 cites W1493606279 @default.
- W2134926481 cites W1520644305 @default.
- W2134926481 cites W1522064770 @default.
- W2134926481 cites W1557627802 @default.
- W2134926481 cites W194875141 @default.
- W2134926481 cites W1964396287 @default.
- W2134926481 cites W1966204777 @default.
- W2134926481 cites W1972635072 @default.
- W2134926481 cites W1974797324 @default.
- W2134926481 cites W1975410659 @default.
- W2134926481 cites W1986152551 @default.
- W2134926481 cites W1991011918 @default.
- W2134926481 cites W1993916665 @default.
- W2134926481 cites W1997451621 @default.
- W2134926481 cites W2002256385 @default.
- W2134926481 cites W2015016494 @default.
- W2134926481 cites W2020925077 @default.
- W2134926481 cites W2025505853 @default.
- W2134926481 cites W204991446 @default.
- W2134926481 cites W2054643353 @default.
- W2134926481 cites W2054795493 @default.
- W2134926481 cites W2054948254 @default.
- W2134926481 cites W2057228803 @default.
- W2134926481 cites W2063896079 @default.
- W2134926481 cites W2072575434 @default.
- W2134926481 cites W2076131096 @default.
- W2134926481 cites W2083616765 @default.
- W2134926481 cites W2086985578 @default.
- W2134926481 cites W2088082120 @default.
- W2134926481 cites W2089521177 @default.
- W2134926481 cites W2096599403 @default.
- W2134926481 cites W2101895029 @default.
- W2134926481 cites W2112299865 @default.
- W2134926481 cites W2131209038 @default.
- W2134926481 cites W2143288276 @default.
- W2134926481 cites W2145499932 @default.
- W2134926481 cites W2148502733 @default.
- W2134926481 cites W2152764495 @default.
- W2134926481 cites W2159772529 @default.
- W2134926481 cites W2165843771 @default.
- W2134926481 cites W4231542564 @default.
- W2134926481 doi "https://doi.org/10.1016/j.jmb.2005.07.024" @default.
- W2134926481 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16095623" @default.
- W2134926481 hasPublicationYear "2005" @default.
- W2134926481 type Work @default.
- W2134926481 sameAs 2134926481 @default.
- W2134926481 citedByCount "30" @default.
- W2134926481 countsByYear W21349264812012 @default.
- W2134926481 countsByYear W21349264812013 @default.
- W2134926481 countsByYear W21349264812014 @default.
- W2134926481 countsByYear W21349264812015 @default.
- W2134926481 countsByYear W21349264812016 @default.
- W2134926481 countsByYear W21349264812018 @default.
- W2134926481 countsByYear W21349264812019 @default.
- W2134926481 countsByYear W21349264812021 @default.
- W2134926481 crossrefType "journal-article" @default.
- W2134926481 hasAuthorship W2134926481A5038647247 @default.
- W2134926481 hasAuthorship W2134926481A5049971572 @default.
- W2134926481 hasAuthorship W2134926481A5065689974 @default.
- W2134926481 hasAuthorship W2134926481A5072521798 @default.
- W2134926481 hasAuthorship W2134926481A5078724396 @default.
- W2134926481 hasConcept C104292427 @default.
- W2134926481 hasConcept C104317684 @default.
- W2134926481 hasConcept C119621388 @default.
- W2134926481 hasConcept C121332964 @default.
- W2134926481 hasConcept C12554922 @default.
- W2134926481 hasConcept C135889238 @default.
- W2134926481 hasConcept C144024400 @default.
- W2134926481 hasConcept C148898269 @default.
- W2134926481 hasConcept C149923435 @default.
- W2134926481 hasConcept C159467904 @default.
- W2134926481 hasConcept C185592680 @default.
- W2134926481 hasConcept C18903297 @default.
- W2134926481 hasConcept C191486275 @default.
- W2134926481 hasConcept C202878990 @default.
- W2134926481 hasConcept C2778517922 @default.
- W2134926481 hasConcept C2908647359 @default.
- W2134926481 hasConcept C55493867 @default.
- W2134926481 hasConcept C62520636 @default.
- W2134926481 hasConcept C8010536 @default.
- W2134926481 hasConcept C86803240 @default.
- W2134926481 hasConceptScore W2134926481C104292427 @default.
- W2134926481 hasConceptScore W2134926481C104317684 @default.
- W2134926481 hasConceptScore W2134926481C119621388 @default.
- W2134926481 hasConceptScore W2134926481C121332964 @default.
- W2134926481 hasConceptScore W2134926481C12554922 @default.
- W2134926481 hasConceptScore W2134926481C135889238 @default.
- W2134926481 hasConceptScore W2134926481C144024400 @default.