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• W2134928110 abstract "Daptomycin pharmacokinetics were evaluated for burn patients. Burn patients had decreases in the maximum concentration of the drug in serum (44%) and the area under the concentration-time curve (47%) and increases in the volume of distribution (64%) and total clearance (77%) compared to healthy volunteers. In burn patients, daptomycin at 10 to 12 mg/kg of body weight/day would be required to achieve drug exposures similar to those for healthy volunteers receiving 6 mg/kg." @default.
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• W2134928110 date "2008-05-01" @default.
• W2134928110 modified "2023-09-26" @default.
• W2134928110 title "Pharmacokinetic Evaluation of Single-Dose Intravenous Daptomycin in Patients with Thermal Burn Injury" @default.
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• W2134928110 doi "https://doi.org/10.1128/aac.01321-07" @default.
• W2134928110 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2346633" @default.
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