Matches in SemOpenAlex for { <https://semopenalex.org/work/W2134965831> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2134965831 endingPage "1139" @default.
- W2134965831 startingPage "1134" @default.
- W2134965831 abstract "The effects of fasting on hepatic prostaglandin E (PGE) receptor characteristics were studied in Sprague-Dawley rats. Plasma membranes were isolated from liver homogenates of animals after 0, 12, 18, 24, and 48 h of fasting. The changes observed in body weight, liver weight, plasma glucose, and plasma beta-hydroxybutyrate during the fast were consistent with those previously reported for a similar fasted rat model. During the transition from the fed to the fasted state there was a decrease in hepatic PGE receptor density (from 0.175 +/- 0.011 pmol bound/mg membrane membrane protein in fed rats to 0.060 +/- 0.009 in rats fasted for 24 h), with no change in binding affinity. This change was observed whether the data were expressed per mg membrane protein isolated or were corrected for total membrane recovery and normalized to initial body weight. Isolated hepatocytes prepared from fed and 24-h fasted animals also demonstrated a significant decrease in PGE-binding site density (from 0.98 +/- 0.05 pmol bound/10(6) cells in fed rats to 0.46 +/- 0.14 in fasted rats), with no change in binding site affinity. The change in binding site density in the hepatocytes was of a magnitude similar to that observed in the liver plasma membranes after the membranes were corrected for recovery and normalized to initial body weight (51% vs. 53%, liver plasma membranes vs. isolated hepatocytes). We conclude that fasting is associated with a decrease in the hepatic PGE receptor density and suggest that this decrease may reflect an increase in hepatic E-series PGs during starvation." @default.
- W2134965831 created "2016-06-24" @default.
- W2134965831 creator A5002808291 @default.
- W2134965831 creator A5059610135 @default.
- W2134965831 date "1987-03-01" @default.
- W2134965831 modified "2023-09-24" @default.
- W2134965831 title "Fasting-Induced Changes in Prostaglandin Binding in Isolated Hepatocytes and Liver Plasma Membranes*" @default.
- W2134965831 cites W1775749144 @default.
- W2134965831 cites W1968636101 @default.
- W2134965831 cites W1974185978 @default.
- W2134965831 cites W1982761340 @default.
- W2134965831 cites W1983538543 @default.
- W2134965831 cites W1983649348 @default.
- W2134965831 cites W1987915694 @default.
- W2134965831 cites W1990540732 @default.
- W2134965831 cites W2001869217 @default.
- W2134965831 cites W2032568692 @default.
- W2134965831 cites W2039495520 @default.
- W2134965831 cites W2044533185 @default.
- W2134965831 cites W2072482644 @default.
- W2134965831 cites W2073212868 @default.
- W2134965831 cites W2076320501 @default.
- W2134965831 cites W2085671830 @default.
- W2134965831 cites W2086049904 @default.
- W2134965831 cites W2137650689 @default.
- W2134965831 cites W2164172489 @default.
- W2134965831 cites W2169503005 @default.
- W2134965831 cites W2285310955 @default.
- W2134965831 cites W2401690367 @default.
- W2134965831 doi "https://doi.org/10.1210/endo-120-3-1134" @default.
- W2134965831 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3467967" @default.
- W2134965831 hasPublicationYear "1987" @default.
- W2134965831 type Work @default.
- W2134965831 sameAs 2134965831 @default.
- W2134965831 citedByCount "12" @default.
- W2134965831 crossrefType "journal-article" @default.
- W2134965831 hasAuthorship W2134965831A5002808291 @default.
- W2134965831 hasAuthorship W2134965831A5059610135 @default.
- W2134965831 hasConcept C107824862 @default.
- W2134965831 hasConcept C126322002 @default.
- W2134965831 hasConcept C134018914 @default.
- W2134965831 hasConcept C170493617 @default.
- W2134965831 hasConcept C185592680 @default.
- W2134965831 hasConcept C202751555 @default.
- W2134965831 hasConcept C2776200302 @default.
- W2134965831 hasConcept C2780664492 @default.
- W2134965831 hasConcept C41625074 @default.
- W2134965831 hasConcept C55493867 @default.
- W2134965831 hasConcept C71924100 @default.
- W2134965831 hasConcept C86803240 @default.
- W2134965831 hasConceptScore W2134965831C107824862 @default.
- W2134965831 hasConceptScore W2134965831C126322002 @default.
- W2134965831 hasConceptScore W2134965831C134018914 @default.
- W2134965831 hasConceptScore W2134965831C170493617 @default.
- W2134965831 hasConceptScore W2134965831C185592680 @default.
- W2134965831 hasConceptScore W2134965831C202751555 @default.
- W2134965831 hasConceptScore W2134965831C2776200302 @default.
- W2134965831 hasConceptScore W2134965831C2780664492 @default.
- W2134965831 hasConceptScore W2134965831C41625074 @default.
- W2134965831 hasConceptScore W2134965831C55493867 @default.
- W2134965831 hasConceptScore W2134965831C71924100 @default.
- W2134965831 hasConceptScore W2134965831C86803240 @default.
- W2134965831 hasIssue "3" @default.
- W2134965831 hasLocation W21349658311 @default.
- W2134965831 hasLocation W21349658312 @default.
- W2134965831 hasOpenAccess W2134965831 @default.
- W2134965831 hasPrimaryLocation W21349658311 @default.
- W2134965831 hasRelatedWork W1996846474 @default.
- W2134965831 hasRelatedWork W2018368842 @default.
- W2134965831 hasRelatedWork W2033472167 @default.
- W2134965831 hasRelatedWork W2034583712 @default.
- W2134965831 hasRelatedWork W2052453588 @default.
- W2134965831 hasRelatedWork W2061429094 @default.
- W2134965831 hasRelatedWork W2063619316 @default.
- W2134965831 hasRelatedWork W2094423915 @default.
- W2134965831 hasRelatedWork W2169225653 @default.
- W2134965831 hasRelatedWork W2414846389 @default.
- W2134965831 hasVolume "120" @default.
- W2134965831 isParatext "false" @default.
- W2134965831 isRetracted "false" @default.
- W2134965831 magId "2134965831" @default.
- W2134965831 workType "article" @default.