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• W2134966239 abstract "<h3>Background:</h3> Previous experimental studies have suggested many possible anti-cancer mechanisms for green tea, but epidemiological evidence for the effect of green tea consumption on gastric cancer risk is conflicting. <h3>Objective:</h3> To examine the association between green tea consumption and gastric cancer. <h3>Methods:</h3> We analysed original data from six cohort studies that measured green tea consumption using validated questionnaires at baseline. Hazard ratios (HRs) in the individual studies were calculated, with adjustment for a common set of variables, and combined using a random-effects model. <h3>Results:</h3> During 2 285 968 person-years of follow-up for a total of 219 080 subjects, 3577 cases of gastric cancer were identified. Compared with those drinking <1 cup/day, no significant risk reduction for gastric cancer was observed with increased green tea consumption in men, even in stratified analyses by smoking status and subsite. In women, however, a significantly decreased risk was observed for those with consumption of ⩾5 cups/day (multivariate-adjusted pooled HR = 0.79, 95% confidence interval (CI) = 0.65 to 0.96). This decrease was also significant for the distal subsite (HR = 0.70, 95% CI = 0.50 to 0.96). In contrast, a lack of association for proximal gastric cancer was consistently seen in both men and women. <h3>Conclusions:</h3> Green tea may decrease the risk of distal gastric cancer in women." @default.
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• W2134966239 date "2009-06-07" @default.
• W2134966239 modified "2023-10-17" @default.
• W2134966239 title "Green tea consumption and gastric cancer in Japanese: a pooled analysis of six cohort studies" @default.
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• W2134966239 doi "https://doi.org/10.1136/gut.2008.166710" @default.
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