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- W2134977237 abstract "Communication between cells ensures coordination of behavior. In prokaryotes, this signaling is usually referred to as quorum sensing, while eukaryotic cells communicate through hormones. In recent years, a growing number of reports have shown that small signaling molecules produced by organisms from different kingdoms of nature can facilitate cross-talk, communication, or signal interference. This trans-kingdom communication (also termed as trans-kingdom signaling or inter-kingdom signaling) mediates symbiotic and pathogenic relationships between various organisms (e.g., microorganisms and their hosts). Strikingly, it has been discovered that microRNAs (miRNAs)—single-stranded noncoding RNAs with an average length of 22 nt—can be transmitted from one species to another, inducing posttranscriptional gene silencing in distant species, even in a cross-kingdom fashion. Here, we discuss several recent studies concerning miRNA-mediated cross-kingdom gene regulation. WIREs RNA 2012 doi: 10.1002/wrna.1127 This article is categorized under: RNA Interactions with Proteins and Other Molecules > Protein–RNA Interactions: Functional Implications Regulatory RNAs/RNAi/Riboswitches > Regulatory RNAs RNA Processing > Capping and 5' End Modifications RNA in Disease and Development > RNA in Development" @default.
- W2134977237 created "2016-06-24" @default.
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- W2134977237 date "2012-06-27" @default.
- W2134977237 modified "2023-09-23" @default.
- W2134977237 title "Regulation of mammalian gene expression by exogenous microRNAs" @default.
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- W2134977237 doi "https://doi.org/10.1002/wrna.1127" @default.
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