FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135020076> ?p ?o ?g. }

• W2135020076 endingPage "3414" @default.
• W2135020076 startingPage "3408" @default.
• W2135020076 abstract "ABSTRACT Haemophilus influenzae is subject to phase variation mediated by changes in the length of simple sequence repeat regions within several genes, most of which encode either surface proteins or enzymes involved in the synthesis of lipopolysaccharides (LPS). The translational repeat regions that have been described thus far all consist of tandemly repeated tetranucleotides. We describe an octanucleotide repeat region within a putative LPS biosynthetic gene, losA . Approximately 20 percent of nontypeable H. influenzae strains contain copies of losA and losB in a genetic locus flanked by infA and ksgA . Of 30 strains containing losA at this site, 24 contained 2 tandem copies of the octanucleotide CGAGCATA, allowing full-length translation of losA (on), and 6 strains contained 3, 4, 6, or 10 tandem copies ( losA off). For a serum-sensitive strain, R3063, with losA off (10 repeat units), selection for serum-resistant variants yielded a heterogeneous population in which colonies with increased serum resistance had losA on (2, 8, or 11 repeat units), and colonies with unchanged sensitivity to serum had 10 repeats. Inactivation of losA in strains R3063 and R2846 (strain 12) by insertion of the cat gene decreased the serum resistance of these strains compared to losA -on variants and altered the electrophoretic mobility of LPS. We conclude that expression of losA , a gene that contributes to LPS structure and affects serum resistance, is determined by octanucleotide repeat variation." @default.
• W2135020076 created "2016-06-24" @default.
• W2135020076 creator A5035168217 @default.
• W2135020076 creator A5038184064 @default.
• W2135020076 creator A5046409365 @default.
• W2135020076 creator A5061999503 @default.
• W2135020076 creator A5062863174 @default.
• W2135020076 creator A5077066310 @default.
• W2135020076 creator A5089952929 @default.
• W2135020076 date "2006-06-01" @default.
• W2135020076 modified "2023-09-26" @default.
• W2135020076 title "Heterogeneity in Tandem Octanucleotides within <i>Haemophilus influenzae</i> Lipopolysaccharide Biosynthetic Gene <i>losA</i> Affects Serum Resistance" @default.
• W2135020076 cites W1499576962 @default.
• W2135020076 cites W1520289893 @default.
• W2135020076 cites W1527704417 @default.
• W2135020076 cites W1608493062 @default.
• W2135020076 cites W1965655901 @default.
• W2135020076 cites W1971403296 @default.
• W2135020076 cites W1984741582 @default.
• W2135020076 cites W1985782125 @default.
• W2135020076 cites W1987292348 @default.
• W2135020076 cites W1992687509 @default.
• W2135020076 cites W1996081765 @default.
• W2135020076 cites W1997524999 @default.
• W2135020076 cites W2012932968 @default.
• W2135020076 cites W2017597673 @default.
• W2135020076 cites W2037193073 @default.
• W2135020076 cites W2047231665 @default.
• W2135020076 cites W2058477464 @default.
• W2135020076 cites W2086996504 @default.
• W2135020076 cites W2111553955 @default.
• W2135020076 cites W2112814753 @default.
• W2135020076 cites W2112927445 @default.
• W2135020076 cites W2114035410 @default.
• W2135020076 cites W2115159819 @default.
• W2135020076 cites W2119538193 @default.
• W2135020076 cites W2119550447 @default.
• W2135020076 cites W2127546816 @default.
• W2135020076 cites W2128380543 @default.
• W2135020076 cites W2135691741 @default.
• W2135020076 cites W2136211808 @default.
• W2135020076 cites W2149373729 @default.
• W2135020076 cites W2149775793 @default.
• W2135020076 cites W2151198139 @default.
• W2135020076 cites W2157976477 @default.
• W2135020076 doi "https://doi.org/10.1128/iai.01540-05" @default.
• W2135020076 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1479228" @default.
• W2135020076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16714571" @default.
• W2135020076 hasPublicationYear "2006" @default.
• W2135020076 type Work @default.
• W2135020076 sameAs 2135020076 @default.
• W2135020076 citedByCount "27" @default.
• W2135020076 countsByYear W21350200762012 @default.
• W2135020076 countsByYear W21350200762013 @default.
• W2135020076 countsByYear W21350200762014 @default.
• W2135020076 countsByYear W21350200762016 @default.
• W2135020076 countsByYear W21350200762018 @default.
• W2135020076 countsByYear W21350200762023 @default.
• W2135020076 crossrefType "journal-article" @default.
• W2135020076 hasAuthorship W2135020076A5035168217 @default.
• W2135020076 hasAuthorship W2135020076A5038184064 @default.
• W2135020076 hasAuthorship W2135020076A5046409365 @default.
• W2135020076 hasAuthorship W2135020076A5061999503 @default.
• W2135020076 hasAuthorship W2135020076A5062863174 @default.
• W2135020076 hasAuthorship W2135020076A5077066310 @default.
• W2135020076 hasAuthorship W2135020076A5089952929 @default.
• W2135020076 hasBestOaLocation W21350200762 @default.
• W2135020076 hasConcept C104317684 @default.
• W2135020076 hasConcept C141231307 @default.
• W2135020076 hasConcept C144024400 @default.
• W2135020076 hasConcept C149923435 @default.
• W2135020076 hasConcept C153911025 @default.
• W2135020076 hasConcept C179069550 @default.
• W2135020076 hasConcept C27149982 @default.
• W2135020076 hasConcept C2776925733 @default.
• W2135020076 hasConcept C2908647359 @default.
• W2135020076 hasConcept C523546767 @default.
• W2135020076 hasConcept C54355233 @default.
• W2135020076 hasConcept C60987743 @default.
• W2135020076 hasConcept C62130838 @default.
• W2135020076 hasConcept C84597430 @default.
• W2135020076 hasConcept C86803240 @default.
• W2135020076 hasConcept C89423630 @default.
• W2135020076 hasConceptScore W2135020076C104317684 @default.
• W2135020076 hasConceptScore W2135020076C141231307 @default.
• W2135020076 hasConceptScore W2135020076C144024400 @default.
• W2135020076 hasConceptScore W2135020076C149923435 @default.
• W2135020076 hasConceptScore W2135020076C153911025 @default.
• W2135020076 hasConceptScore W2135020076C179069550 @default.
• W2135020076 hasConceptScore W2135020076C27149982 @default.
• W2135020076 hasConceptScore W2135020076C2776925733 @default.
• W2135020076 hasConceptScore W2135020076C2908647359 @default.
• W2135020076 hasConceptScore W2135020076C523546767 @default.
• W2135020076 hasConceptScore W2135020076C54355233 @default.
• W2135020076 hasConceptScore W2135020076C60987743 @default.
• W2135020076 hasConceptScore W2135020076C62130838 @default.
• W2135020076 hasConceptScore W2135020076C84597430 @default.
• W2135020076 hasConceptScore W2135020076C86803240 @default.

• next