FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135044594> ?p ?o ?g. }

• W2135044594 endingPage "659" @default.
• W2135044594 startingPage "655" @default.
• W2135044594 abstract "Metabolic abnormalities, including impairment of glucose homeostasis, have been well characterized in HIV-infected patients. In contrast to adults, insulin resistance and diabetes mellitus appear to be relatively uncommon finding in youth.We assessed insulin resistance, and associated risk factors, in a population of vertically HIV-infected children and young adults, when compared with a control population of healthy children.At the time of enrolment, weeks of pregnancy, birth weight, sex, age, weight, height, body mass index (BMI), pubertal stages, CDC classification, blood pressure, clinical lipodystrophy, hepatitis B or C co-infection, antiretroviral therapy, CD4 T lymphocyte counts, and HIV-RNA levels were recorded. Fasting plasma glucose and insulin levels and homeostatic model assessment-insulin resistance (HOMA-IR) were determined. These parameters were compared between HIV patients and healthy controls with multivariate analyses.Fasting insulin levels (OR=1.21, P<0.001) and glycemia (OR=0.89, P<0.001) were significantly different between HIV-infected patients and controls. Antiretroviral therapy duration (r=0.281, P<0.05), triglyceride levels (r=0.286, P<0.05), age (r=0.299, P<0.05), and BMI SDS (r=0.485, P<0.001) were significant predictor variables of insulin resistance, expressed as HOMA-IR. Moreover, clinical lipodystrophy seems to be strongly correlated to glycemia (P<0.05), triglyceride levels (P<0.05), serum insulin levels (P<0.001), HOMA-IR (P<0.05), and also with therapy duration (P<0.05).Both HIV infection and antiretroviral therapy demonstrate differential effects on glucose metabolism in HIV-infected children. Targeted prevention of insulin resistance and diabetes mellitus in HIV-infected children and young adults is needed in order to avoid the associated long-term complications that would otherwise occur, given the improvement in life expectancy of HIV-infected individuals." @default.
• W2135044594 created "2016-06-24" @default.
• W2135044594 creator A5015544677 @default.
• W2135044594 creator A5017885138 @default.
• W2135044594 creator A5025782579 @default.
• W2135044594 creator A5027655486 @default.
• W2135044594 creator A5028875156 @default.
• W2135044594 creator A5031754069 @default.
• W2135044594 creator A5036034386 @default.
• W2135044594 creator A5041930025 @default.
• W2135044594 creator A5058024552 @default.
• W2135044594 creator A5086571402 @default.
• W2135044594 date "2007-11-01" @default.
• W2135044594 modified "2023-10-17" @default.
• W2135044594 title "Evaluation of insulin resistance in a cohort of HIV-infected youth" @default.
• W2135044594 cites W1486704179 @default.
• W2135044594 cites W1950185295 @default.
• W2135044594 cites W1965153851 @default.
• W2135044594 cites W1976022560 @default.
• W2135044594 cites W1988829185 @default.
• W2135044594 cites W2007061668 @default.
• W2135044594 cites W2026546405 @default.
• W2135044594 cites W2030108212 @default.
• W2135044594 cites W2035586426 @default.
• W2135044594 cites W2048018726 @default.
• W2135044594 cites W2061496424 @default.
• W2135044594 cites W2068899490 @default.
• W2135044594 cites W2076768567 @default.
• W2135044594 cites W2080507282 @default.
• W2135044594 cites W2090963139 @default.
• W2135044594 cites W2092014129 @default.
• W2135044594 cites W2133417811 @default.
• W2135044594 cites W2135032077 @default.
• W2135044594 cites W2135138105 @default.
• W2135044594 cites W2142932338 @default.
• W2135044594 cites W2144485854 @default.
• W2135044594 cites W2467047110 @default.
• W2135044594 cites W4238766605 @default.
• W2135044594 cites W4250274096 @default.
• W2135044594 cites W4253923586 @default.
• W2135044594 doi "https://doi.org/10.1530/eje-07-0414" @default.
• W2135044594 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17984246" @default.
• W2135044594 hasPublicationYear "2007" @default.
• W2135044594 type Work @default.
• W2135044594 sameAs 2135044594 @default.
• W2135044594 citedByCount "28" @default.
• W2135044594 countsByYear W21350445942013 @default.
• W2135044594 countsByYear W21350445942014 @default.
• W2135044594 countsByYear W21350445942015 @default.
• W2135044594 countsByYear W21350445942016 @default.
• W2135044594 countsByYear W21350445942017 @default.
• W2135044594 countsByYear W21350445942018 @default.
• W2135044594 countsByYear W21350445942019 @default.
• W2135044594 countsByYear W21350445942020 @default.
• W2135044594 countsByYear W21350445942021 @default.
• W2135044594 crossrefType "journal-article" @default.
• W2135044594 hasAuthorship W2135044594A5015544677 @default.
• W2135044594 hasAuthorship W2135044594A5017885138 @default.
• W2135044594 hasAuthorship W2135044594A5025782579 @default.
• W2135044594 hasAuthorship W2135044594A5027655486 @default.
• W2135044594 hasAuthorship W2135044594A5028875156 @default.
• W2135044594 hasAuthorship W2135044594A5031754069 @default.
• W2135044594 hasAuthorship W2135044594A5036034386 @default.
• W2135044594 hasAuthorship W2135044594A5041930025 @default.
• W2135044594 hasAuthorship W2135044594A5058024552 @default.
• W2135044594 hasAuthorship W2135044594A5086571402 @default.
• W2135044594 hasBestOaLocation W21350445941 @default.
• W2135044594 hasConcept C126322002 @default.
• W2135044594 hasConcept C134018914 @default.
• W2135044594 hasConcept C142462285 @default.
• W2135044594 hasConcept C203014093 @default.
• W2135044594 hasConcept C2777391703 @default.
• W2135044594 hasConcept C2778163477 @default.
• W2135044594 hasConcept C2778535154 @default.
• W2135044594 hasConcept C2778913445 @default.
• W2135044594 hasConcept C2779306644 @default.
• W2135044594 hasConcept C2780221984 @default.
• W2135044594 hasConcept C2780941825 @default.
• W2135044594 hasConcept C2908647359 @default.
• W2135044594 hasConcept C2993143319 @default.
• W2135044594 hasConcept C3013748606 @default.
• W2135044594 hasConcept C555293320 @default.
• W2135044594 hasConcept C71924100 @default.
• W2135044594 hasConcept C99454951 @default.
• W2135044594 hasConceptScore W2135044594C126322002 @default.
• W2135044594 hasConceptScore W2135044594C134018914 @default.
• W2135044594 hasConceptScore W2135044594C142462285 @default.
• W2135044594 hasConceptScore W2135044594C203014093 @default.
• W2135044594 hasConceptScore W2135044594C2777391703 @default.
• W2135044594 hasConceptScore W2135044594C2778163477 @default.
• W2135044594 hasConceptScore W2135044594C2778535154 @default.
• W2135044594 hasConceptScore W2135044594C2778913445 @default.
• W2135044594 hasConceptScore W2135044594C2779306644 @default.
• W2135044594 hasConceptScore W2135044594C2780221984 @default.
• W2135044594 hasConceptScore W2135044594C2780941825 @default.
• W2135044594 hasConceptScore W2135044594C2908647359 @default.
• W2135044594 hasConceptScore W2135044594C2993143319 @default.
• W2135044594 hasConceptScore W2135044594C3013748606 @default.

• next