Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135087011> ?p ?o ?g. }
- W2135087011 endingPage "1622" @default.
- W2135087011 startingPage "1616" @default.
- W2135087011 abstract "ABSTRACT We have characterized a major regulatory element of ground squirrel hepatitis virus (GSHV) located within a 90-nucleotide fragment of the core promoter upstream sequences and have compared its organization to that of woodchuck hepatitis virus (WHV) enhancer II (We2). The GSHV element (Ge2) stimulates transcription from the viral core promoter and heterologous promoters in an orientation-independent manner but displays a lower level of activity than We2 in transient transfection assays in human hepatoma cells. The general organization of Ge2 into binding sites for the liver-enriched HNF-1 and HNF-4 proteins and for ubiquitous factors of the NF1 and Oct families was found to be mostly conserved with respect to the homologous We2 region. Accordingly, transactivation by HNF-1 and HNF-4 plays an essential role in the liver-specific transcriptional activity of both the GSHV and WHV core promoters. Distinctive features of the GSHV enhancer consist of its ability to bind C/EBP family factors in a central motif that overlaps with one of the two HNF-4 sites and its differential binding affinities for HNF-4." @default.
- W2135087011 created "2016-06-24" @default.
- W2135087011 creator A5003120349 @default.
- W2135087011 creator A5017310909 @default.
- W2135087011 creator A5058031113 @default.
- W2135087011 creator A5061972994 @default.
- W2135087011 creator A5091558539 @default.
- W2135087011 date "1998-02-01" @default.
- W2135087011 modified "2023-09-25" @default.
- W2135087011 title "Functional Analysis of Ground Squirrel Hepatitis Virus Enhancer II" @default.
- W2135087011 cites W11602674 @default.
- W2135087011 cites W117387909 @default.
- W2135087011 cites W1427850581 @default.
- W2135087011 cites W1485144497 @default.
- W2135087011 cites W1495876720 @default.
- W2135087011 cites W1578555932 @default.
- W2135087011 cites W1611884612 @default.
- W2135087011 cites W1661434665 @default.
- W2135087011 cites W1841361350 @default.
- W2135087011 cites W1902381992 @default.
- W2135087011 cites W1912385731 @default.
- W2135087011 cites W1929153087 @default.
- W2135087011 cites W1954373135 @default.
- W2135087011 cites W1970968166 @default.
- W2135087011 cites W1973912514 @default.
- W2135087011 cites W1974281044 @default.
- W2135087011 cites W1985784851 @default.
- W2135087011 cites W1997816609 @default.
- W2135087011 cites W2005019916 @default.
- W2135087011 cites W2024668373 @default.
- W2135087011 cites W2031698517 @default.
- W2135087011 cites W2033522034 @default.
- W2135087011 cites W2052548885 @default.
- W2135087011 cites W2058312859 @default.
- W2135087011 cites W2060695079 @default.
- W2135087011 cites W2072683091 @default.
- W2135087011 cites W2077261780 @default.
- W2135087011 cites W2089369839 @default.
- W2135087011 cites W2097805530 @default.
- W2135087011 cites W2101448549 @default.
- W2135087011 cites W2113180849 @default.
- W2135087011 cites W2122709844 @default.
- W2135087011 cites W2141313102 @default.
- W2135087011 cites W2145218360 @default.
- W2135087011 cites W2153017169 @default.
- W2135087011 cites W2159146123 @default.
- W2135087011 cites W2170242075 @default.
- W2135087011 cites W2199170296 @default.
- W2135087011 cites W2341022548 @default.
- W2135087011 cites W38016356 @default.
- W2135087011 cites W4239135224 @default.
- W2135087011 cites W4256208404 @default.
- W2135087011 doi "https://doi.org/10.1128/jvi.72.2.1616-1622.1998" @default.
- W2135087011 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/124644" @default.
- W2135087011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9445066" @default.
- W2135087011 hasPublicationYear "1998" @default.
- W2135087011 type Work @default.
- W2135087011 sameAs 2135087011 @default.
- W2135087011 citedByCount "0" @default.
- W2135087011 crossrefType "journal-article" @default.
- W2135087011 hasAuthorship W2135087011A5003120349 @default.
- W2135087011 hasAuthorship W2135087011A5017310909 @default.
- W2135087011 hasAuthorship W2135087011A5058031113 @default.
- W2135087011 hasAuthorship W2135087011A5061972994 @default.
- W2135087011 hasAuthorship W2135087011A5091558539 @default.
- W2135087011 hasBestOaLocation W21350870111 @default.
- W2135087011 hasConcept C101762097 @default.
- W2135087011 hasConcept C104317684 @default.
- W2135087011 hasConcept C107824862 @default.
- W2135087011 hasConcept C111936080 @default.
- W2135087011 hasConcept C1292079 @default.
- W2135087011 hasConcept C138885662 @default.
- W2135087011 hasConcept C150194340 @default.
- W2135087011 hasConcept C153911025 @default.
- W2135087011 hasConcept C159047783 @default.
- W2135087011 hasConcept C179926584 @default.
- W2135087011 hasConcept C21592294 @default.
- W2135087011 hasConcept C2522874641 @default.
- W2135087011 hasConcept C2780115692 @default.
- W2135087011 hasConcept C2780593183 @default.
- W2135087011 hasConcept C2780617729 @default.
- W2135087011 hasConcept C2781079990 @default.
- W2135087011 hasConcept C41895202 @default.
- W2135087011 hasConcept C54355233 @default.
- W2135087011 hasConcept C86339819 @default.
- W2135087011 hasConcept C86803240 @default.
- W2135087011 hasConceptScore W2135087011C101762097 @default.
- W2135087011 hasConceptScore W2135087011C104317684 @default.
- W2135087011 hasConceptScore W2135087011C107824862 @default.
- W2135087011 hasConceptScore W2135087011C111936080 @default.
- W2135087011 hasConceptScore W2135087011C1292079 @default.
- W2135087011 hasConceptScore W2135087011C138885662 @default.
- W2135087011 hasConceptScore W2135087011C150194340 @default.
- W2135087011 hasConceptScore W2135087011C153911025 @default.
- W2135087011 hasConceptScore W2135087011C159047783 @default.
- W2135087011 hasConceptScore W2135087011C179926584 @default.
- W2135087011 hasConceptScore W2135087011C21592294 @default.
- W2135087011 hasConceptScore W2135087011C2522874641 @default.