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• W2135124067 startingPage "3529" @default.
• W2135124067 abstract "In spite of the long-term interest in the process of balancing selection, its frequency in genomes and evolutionary significance remain unclear due to challenges related to its detection. Current statistical approaches based on patterns of variation observed in molecular data suffer from low power and a high incidence of false positives. This raises the question whether balancing selection is rare or is simply difficult to detect. We discuss genetic signatures produced by this mode of selection and review the current approaches used for their identification in genomes. Advantages and disadvantages of the available methods are presented, and areas where improvement is possible are identified. Increased specificity and reduced rate of false positives may be achieved by using a demographic model, applying combinations of tests, appropriate sampling scheme and taking into account intralocus variation in selection pressures. We emphasize novel solutions, recently developed model-based approaches and good practices that should be implemented in future studies looking for signals of balancing selection. We also draw attention of the readers to the results of recent theoretical studies, which suggest that balancing selection may be ubiquitous but transient, leaving few signatures detectable by existing methods. Testing this new theory may require the development of novel high-throughput methods extending beyond genomic scans." @default.
• W2135124067 created "2016-06-24" @default.
• W2135124067 creator A5024869766 @default.
• W2135124067 creator A5055402697 @default.
• W2135124067 date "2015-06-15" @default.
• W2135124067 modified "2023-10-06" @default.
• W2135124067 title "Detecting balancing selection in genomes: limits and prospects" @default.
• W2135124067 cites W118842673 @default.
• W2135124067 cites W1496529822 @default.
• W2135124067 cites W1519609773 @default.
• W2135124067 cites W1572265772 @default.
• W2135124067 cites W1584565635 @default.
• W2135124067 cites W1791417164 @default.
• W2135124067 cites W1858573497 @default.
• W2135124067 cites W1869520791 @default.
• W2135124067 cites W1888844519 @default.
• W2135124067 cites W1892029173 @default.
• W2135124067 cites W1908004740 @default.
• W2135124067 cites W1927833699 @default.
• W2135124067 cites W1929921649 @default.
• W2135124067 cites W1964205186 @default.
• W2135124067 cites W1965104903 @default.
• W2135124067 cites W1965236503 @default.
• W2135124067 cites W1968410889 @default.
• W2135124067 cites W1968552986 @default.
• W2135124067 cites W1969664539 @default.
• W2135124067 cites W1972531558 @default.
• W2135124067 cites W1980887908 @default.
• W2135124067 cites W1982603712 @default.
• W2135124067 cites W1985993046 @default.
• W2135124067 cites W1986417764 @default.
• W2135124067 cites W1990352386 @default.
• W2135124067 cites W1999169677 @default.
• W2135124067 cites W2006189274 @default.
• W2135124067 cites W2006890333 @default.
• W2135124067 cites W2009148864 @default.
• W2135124067 cites W2009441527 @default.
• W2135124067 cites W2014094060 @default.
• W2135124067 cites W2022411860 @default.
• W2135124067 cites W2022984183 @default.
• W2135124067 cites W2023670697 @default.
• W2135124067 cites W2024745007 @default.
• W2135124067 cites W2025253353 @default.
• W2135124067 cites W2029447690 @default.
• W2135124067 cites W2033754587 @default.
• W2135124067 cites W2033819183 @default.
• W2135124067 cites W2036507199 @default.
• W2135124067 cites W2036762868 @default.
• W2135124067 cites W2038464976 @default.
• W2135124067 cites W2039435867 @default.
• W2135124067 cites W2039656278 @default.
• W2135124067 cites W2040563586 @default.
• W2135124067 cites W2041583082 @default.
• W2135124067 cites W2045641296 @default.
• W2135124067 cites W2047141393 @default.
• W2135124067 cites W2050276404 @default.
• W2135124067 cites W2050340111 @default.
• W2135124067 cites W2055543630 @default.
• W2135124067 cites W2055875318 @default.
• W2135124067 cites W2057158738 @default.
• W2135124067 cites W2057872622 @default.
• W2135124067 cites W2062984704 @default.
• W2135124067 cites W2063733088 @default.
• W2135124067 cites W2064015470 @default.
• W2135124067 cites W2065890256 @default.
• W2135124067 cites W2067058184 @default.
• W2135124067 cites W2072201802 @default.
• W2135124067 cites W2075804448 @default.
• W2135124067 cites W2081081160 @default.
• W2135124067 cites W2082338381 @default.
• W2135124067 cites W2084152659 @default.
• W2135124067 cites W2085199608 @default.
• W2135124067 cites W2090459727 @default.
• W2135124067 cites W2095672786 @default.
• W2135124067 cites W2095779837 @default.
• W2135124067 cites W2099329037 @default.
• W2135124067 cites W2100184529 @default.
• W2135124067 cites W2100957776 @default.
• W2135124067 cites W2101875882 @default.
• W2135124067 cites W2101983588 @default.
• W2135124067 cites W2102327637 @default.
• W2135124067 cites W2103286878 @default.
• W2135124067 cites W2103809514 @default.
• W2135124067 cites W2105722921 @default.
• W2135124067 cites W2109005999 @default.
• W2135124067 cites W2109183238 @default.
• W2135124067 cites W2109195195 @default.
• W2135124067 cites W2112476384 @default.
• W2135124067 cites W2113256460 @default.
• W2135124067 cites W2116416291 @default.
• W2135124067 cites W2116668053 @default.
• W2135124067 cites W2116839011 @default.
• W2135124067 cites W2117189386 @default.
• W2135124067 cites W2118055782 @default.
• W2135124067 cites W2118231722 @default.
• W2135124067 cites W2119191730 @default.
• W2135124067 cites W2120309759 @default.
• W2135124067 cites W2122003337 @default.

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