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- W2135182134 abstract "Although the absolute proportion of severe diarrhoeal disease prevented is still much higher in the African setting, the relative poor performance of enteric vaccines in these populations deserves further mechanistic study.Two issues deserve consideration in assessing this vaccine in low-income, high-burden countries. First, although use of the endpoint of severe diarrhoea across sites provides standardisation, diff erences in care-seeking behaviour and out-of-pocket payment for paediatric health-care services in some settings could compromise case ascertainment.Second, rotavirus infection is a systemic illness with diarrhoea as the predominant manifestation. There are many reports of extraintestinal mani festations of rotavirus infection in children," @default.
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- W2135182134 date "2010-12-01" @default.
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- W2135182134 title "Rotavirus vaccine efficacy in African and Asian countries" @default.
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- W2135182134 doi "https://doi.org/10.1016/s0140-6736(10)62206-4" @default.
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