Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135202053> ?p ?o ?g. }
- W2135202053 endingPage "1377" @default.
- W2135202053 startingPage "1371" @default.
- W2135202053 abstract "Modulation of NK activity of PBLs from ALL patients was studied following exposure to IFN-alpha, staphylococcal protein A and interleukin-2. Only 52% of ALL patients responded to IFN-alpha stimulation, where the majority of controls showed positive enhancement of NK activity. Protein A failed to cause a significant stimulation of ALL patient PBLs whereas all controls showed a positive response. The majority of ALL patient and child control PBLs were however able to produce significant levels of IFN-gamma (protein A stimulation) and IFN-alpha (Sendai virus stimulation), although significantly more of both types of interferon could be induced in adult PBL samples. The ability of IL-2 to activate NK activity of ALL PBL samples showed a similar trend to IFN-alpha stimulation; thus, not all ALL patients showed positive augmentation of NK activity upon IL-2 stimulation. It is clear from these results that interferons and IL-2 may not necessarily lead to activated NK cytolytic activity, and in the present study approx. 50% of ALL patients failed to respond to lymphokine stimulation." @default.
- W2135202053 created "2016-06-24" @default.
- W2135202053 creator A5014842076 @default.
- W2135202053 creator A5022787118 @default.
- W2135202053 creator A5069665879 @default.
- W2135202053 creator A5076442089 @default.
- W2135202053 date "1987-09-01" @default.
- W2135202053 modified "2023-10-18" @default.
- W2135202053 title "Immunomodulation of natural killer activity in children with acute lymphoblastic leukaemia" @default.
- W2135202053 cites W1496255841 @default.
- W2135202053 cites W1534220439 @default.
- W2135202053 cites W1556252201 @default.
- W2135202053 cites W1562945187 @default.
- W2135202053 cites W1582089166 @default.
- W2135202053 cites W1653924208 @default.
- W2135202053 cites W1920873020 @default.
- W2135202053 cites W1979343444 @default.
- W2135202053 cites W1981586091 @default.
- W2135202053 cites W1988349837 @default.
- W2135202053 cites W1991360369 @default.
- W2135202053 cites W2002313968 @default.
- W2135202053 cites W2003464992 @default.
- W2135202053 cites W2008338915 @default.
- W2135202053 cites W2022285897 @default.
- W2135202053 cites W2034056616 @default.
- W2135202053 cites W2037849908 @default.
- W2135202053 cites W2041837132 @default.
- W2135202053 cites W2044025468 @default.
- W2135202053 cites W2063448006 @default.
- W2135202053 cites W2070229745 @default.
- W2135202053 cites W2088740471 @default.
- W2135202053 cites W2089259667 @default.
- W2135202053 cites W2100673560 @default.
- W2135202053 cites W2109794500 @default.
- W2135202053 cites W2117735867 @default.
- W2135202053 cites W2238025998 @default.
- W2135202053 cites W2318163315 @default.
- W2135202053 cites W2412356640 @default.
- W2135202053 cites W2440058403 @default.
- W2135202053 doi "https://doi.org/10.1016/0277-5379(87)90122-2" @default.
- W2135202053 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3500050" @default.
- W2135202053 hasPublicationYear "1987" @default.
- W2135202053 type Work @default.
- W2135202053 sameAs 2135202053 @default.
- W2135202053 citedByCount "2" @default.
- W2135202053 crossrefType "journal-article" @default.
- W2135202053 hasAuthorship W2135202053A5014842076 @default.
- W2135202053 hasAuthorship W2135202053A5022787118 @default.
- W2135202053 hasAuthorship W2135202053A5069665879 @default.
- W2135202053 hasAuthorship W2135202053A5076442089 @default.
- W2135202053 hasConcept C109316439 @default.
- W2135202053 hasConcept C126322002 @default.
- W2135202053 hasConcept C159110408 @default.
- W2135202053 hasConcept C202751555 @default.
- W2135202053 hasConcept C203014093 @default.
- W2135202053 hasConcept C24998067 @default.
- W2135202053 hasConcept C2522874641 @default.
- W2135202053 hasConcept C2775944032 @default.
- W2135202053 hasConcept C2776178377 @default.
- W2135202053 hasConcept C2780127873 @default.
- W2135202053 hasConcept C49382859 @default.
- W2135202053 hasConcept C49453240 @default.
- W2135202053 hasConcept C55493867 @default.
- W2135202053 hasConcept C64943373 @default.
- W2135202053 hasConcept C71924100 @default.
- W2135202053 hasConcept C73588182 @default.
- W2135202053 hasConcept C86803240 @default.
- W2135202053 hasConcept C8891405 @default.
- W2135202053 hasConceptScore W2135202053C109316439 @default.
- W2135202053 hasConceptScore W2135202053C126322002 @default.
- W2135202053 hasConceptScore W2135202053C159110408 @default.
- W2135202053 hasConceptScore W2135202053C202751555 @default.
- W2135202053 hasConceptScore W2135202053C203014093 @default.
- W2135202053 hasConceptScore W2135202053C24998067 @default.
- W2135202053 hasConceptScore W2135202053C2522874641 @default.
- W2135202053 hasConceptScore W2135202053C2775944032 @default.
- W2135202053 hasConceptScore W2135202053C2776178377 @default.
- W2135202053 hasConceptScore W2135202053C2780127873 @default.
- W2135202053 hasConceptScore W2135202053C49382859 @default.
- W2135202053 hasConceptScore W2135202053C49453240 @default.
- W2135202053 hasConceptScore W2135202053C55493867 @default.
- W2135202053 hasConceptScore W2135202053C64943373 @default.
- W2135202053 hasConceptScore W2135202053C71924100 @default.
- W2135202053 hasConceptScore W2135202053C73588182 @default.
- W2135202053 hasConceptScore W2135202053C86803240 @default.
- W2135202053 hasConceptScore W2135202053C8891405 @default.
- W2135202053 hasIssue "9" @default.
- W2135202053 hasLocation W21352020531 @default.
- W2135202053 hasLocation W21352020532 @default.
- W2135202053 hasOpenAccess W2135202053 @default.
- W2135202053 hasPrimaryLocation W21352020531 @default.
- W2135202053 hasRelatedWork W143528160 @default.
- W2135202053 hasRelatedWork W1631214664 @default.
- W2135202053 hasRelatedWork W1642658014 @default.
- W2135202053 hasRelatedWork W1932808662 @default.
- W2135202053 hasRelatedWork W2009193852 @default.
- W2135202053 hasRelatedWork W2072913773 @default.
- W2135202053 hasRelatedWork W2091552406 @default.