FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135277595> ?p ?o ?g. }

• W2135277595 endingPage "157" @default.
• W2135277595 startingPage "151" @default.
• W2135277595 abstract "Supercritical fluid extraction (SFE) of daphnoretin, 7-methoxy-daphnoretin and 1,5-diphenyl-1- pentanone from Stellera chamaejasme L. was performed. An orthogonal L9 (3)4 test design was applied to select the optimum extraction parameters including pressure, temperature, modifier and sample particle size on yield using an analytical-scale SFE system. The process was then scaled up by 100 times using a preparative SFE system under the optimized conditions of 25 MPa of pressure, 45 °C of temperature, 40–60 mesh of sample particle size and modified CO2 with 20% methanol. The yield of the crude extract from preparative SFE was 2.65%, which contained daphnoretin 25.2%, 7-methoxy-daphnoretin 22.8% and 1,5-diphenyl-1-pentanone 21.1%, respectively. Then the crude extract was successfully isolated and separated by preparative high-speed counter-current chromatography (HSCCC) with a two-phase solvent system composed of n-hexane–ethyl acetate–methanol–water (10:13:13:10, v/v) by increasing the flow-rate of the mobile phase stepwise from 1.0 to 2.0 ml/min after 90 min. The target compounds isolated and purified by HSCCC were analyzed by high-performance liquid chromatography (HPLC). The separation produced total of 69.2 mg of daphnoretin at 99.2% purity, 63.4 mg of 7-methoxy-daphnoretin at 98.7% purity and 58.3 mg of 1,5-diphenyl-1-pentanone at 98.1% purity from 300 mg of the crude extract in one-step separation. The recoveries of daphnoretin, 7-methoxy-daphnoretin and 1,5-diphenyl-1-pentanone were 90.8, 91.5 and 90.4%, respectively, in HSCCC isolation step and the chemical structure identification was carried out by MS, 1H NMR and 13C NMR." @default.
• W2135277595 created "2016-06-24" @default.
• W2135277595 creator A5020655470 @default.
• W2135277595 creator A5028310890 @default.
• W2135277595 creator A5036064136 @default.
• W2135277595 creator A5059388246 @default.
• W2135277595 creator A5065801806 @default.
• W2135277595 creator A5076653718 @default.
• W2135277595 creator A5077584441 @default.
• W2135277595 creator A5083629023 @default.
• W2135277595 creator A5091253676 @default.
• W2135277595 date "2006-12-01" @default.
• W2135277595 modified "2023-10-18" @default.
• W2135277595 title "Orthogonal test design for optimization of supercritical fluid extraction of daphnoretin, 7-methoxy-daphnoretin and 1,5-diphenyl-1-pentanone from Stellera chamaejasme L. and subsequent isolation by high-speed counter-current chromatography" @default.
• W2135277595 cites W1973056231 @default.
• W2135277595 cites W1978111359 @default.
• W2135277595 cites W1984297788 @default.
• W2135277595 cites W1990673132 @default.
• W2135277595 cites W1992236831 @default.
• W2135277595 cites W2012366930 @default.
• W2135277595 cites W2012620412 @default.
• W2135277595 cites W2016962159 @default.
• W2135277595 cites W2028788583 @default.
• W2135277595 cites W2030514272 @default.
• W2135277595 cites W2042669418 @default.
• W2135277595 cites W2047060062 @default.
• W2135277595 cites W2053171398 @default.
• W2135277595 cites W2080688595 @default.
• W2135277595 cites W2102006603 @default.
• W2135277595 cites W2102714815 @default.
• W2135277595 cites W2112991946 @default.
• W2135277595 cites W4241439347 @default.
• W2135277595 doi "https://doi.org/10.1016/j.chroma.2006.08.099" @default.
• W2135277595 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17070822" @default.
• W2135277595 hasPublicationYear "2006" @default.
• W2135277595 type Work @default.
• W2135277595 sameAs 2135277595 @default.
• W2135277595 citedByCount "51" @default.
• W2135277595 countsByYear W21352775952012 @default.
• W2135277595 countsByYear W21352775952013 @default.
• W2135277595 countsByYear W21352775952014 @default.
• W2135277595 countsByYear W21352775952015 @default.
• W2135277595 countsByYear W21352775952016 @default.
• W2135277595 countsByYear W21352775952017 @default.
• W2135277595 countsByYear W21352775952018 @default.
• W2135277595 countsByYear W21352775952019 @default.
• W2135277595 countsByYear W21352775952020 @default.
• W2135277595 countsByYear W21352775952021 @default.
• W2135277595 countsByYear W21352775952022 @default.
• W2135277595 countsByYear W21352775952023 @default.
• W2135277595 crossrefType "journal-article" @default.
• W2135277595 hasAuthorship W2135277595A5020655470 @default.
• W2135277595 hasAuthorship W2135277595A5028310890 @default.
• W2135277595 hasAuthorship W2135277595A5036064136 @default.
• W2135277595 hasAuthorship W2135277595A5059388246 @default.
• W2135277595 hasAuthorship W2135277595A5065801806 @default.
• W2135277595 hasAuthorship W2135277595A5076653718 @default.
• W2135277595 hasAuthorship W2135277595A5077584441 @default.
• W2135277595 hasAuthorship W2135277595A5083629023 @default.
• W2135277595 hasAuthorship W2135277595A5091253676 @default.
• W2135277595 hasConcept C113196181 @default.
• W2135277595 hasConcept C118419359 @default.
• W2135277595 hasConcept C134121241 @default.
• W2135277595 hasConcept C178790620 @default.
• W2135277595 hasConcept C185592680 @default.
• W2135277595 hasConcept C191897082 @default.
• W2135277595 hasConcept C192562407 @default.
• W2135277595 hasConcept C2779607525 @default.
• W2135277595 hasConcept C43617362 @default.
• W2135277595 hasConcept C4725764 @default.
• W2135277595 hasConceptScore W2135277595C113196181 @default.
• W2135277595 hasConceptScore W2135277595C118419359 @default.
• W2135277595 hasConceptScore W2135277595C134121241 @default.
• W2135277595 hasConceptScore W2135277595C178790620 @default.
• W2135277595 hasConceptScore W2135277595C185592680 @default.
• W2135277595 hasConceptScore W2135277595C191897082 @default.
• W2135277595 hasConceptScore W2135277595C192562407 @default.
• W2135277595 hasConceptScore W2135277595C2779607525 @default.
• W2135277595 hasConceptScore W2135277595C43617362 @default.
• W2135277595 hasConceptScore W2135277595C4725764 @default.
• W2135277595 hasIssue "2" @default.
• W2135277595 hasLocation W21352775951 @default.
• W2135277595 hasLocation W21352775952 @default.
• W2135277595 hasOpenAccess W2135277595 @default.
• W2135277595 hasPrimaryLocation W21352775951 @default.
• W2135277595 hasRelatedWork W2025745156 @default.
• W2135277595 hasRelatedWork W2027625156 @default.
• W2135277595 hasRelatedWork W2110306891 @default.
• W2135277595 hasRelatedWork W2151819095 @default.
• W2135277595 hasRelatedWork W2351640234 @default.
• W2135277595 hasRelatedWork W2401463829 @default.
• W2135277595 hasRelatedWork W2949184651 @default.
• W2135277595 hasRelatedWork W2952649848 @default.
• W2135277595 hasRelatedWork W828661296 @default.
• W2135277595 hasRelatedWork W2121404800 @default.
• W2135277595 hasVolume "1135" @default.
• W2135277595 isParatext "false" @default.
• W2135277595 isRetracted "false" @default.

• next