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- W2135280497 abstract "Fluorescence-labeled glycoconjugate polymers carrying carbohydrate segments of a globotriaosyl ceramide (Gb3) were synthesized and subjected to biological assays using Escherichia coli O-157 strains and Shiga-like toxins (Stx-I and Stx-II). For the fluorescence labeling, a new polymerizable fluorescent monomer with a TBMB carbonyl chromophore (Ex. 325 nm, Em. 410 nm) was designed. A glycosyl monomer of the trisaccharide segment of Gb3 was prepared from p-nitrophenyl β-lactoside and copolymerized with acrylamide and the fluorescent monomer to prepare a fluorescence-labeled glycoconjugate copolymer carrying [α-d-galactopyranosyl-(1→)-β-d-galactopyranosyl]-(1→)-β-d-glucopyranoside. The polymer showed potent neutralization activity against Stx-I and also binding activity onto E. coli O-157 strains." @default.
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- W2135280497 date "1999-09-01" @default.
- W2135280497 modified "2023-10-16" @default.
- W2135280497 title "Synthesis of an artificial glycoconjugate polymer carrying P k -antigenic trisaccharide and its potent neutralization activity against Shiga-like toxin" @default.
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- W2135280497 doi "https://doi.org/10.1016/s0968-0896(99)00129-7" @default.
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