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- W2135322597 abstract "The ability of a killed phase I Coxiella burnetii vaccine to induce cell-mediated immune responses in guinea pigs was studied. Cell-mediated immune responses were assessed by the inhibition of macrophage migration and lymphocyte transformation assays. The macrophage migration response occurred rapidly and was detected at high levels, but was relatively short-lived. In contrast, the lymphocyte transformation response developed more slowly, and persisted for a longer period. The vaccine, given in a single dose or in two doses 1 week apart, protected guinea pigs from a subsequent virulent challenge." @default.
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- W2135322597 date "1978-01-01" @default.
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- W2135322597 title "Cell-mediated immune responses of guinea pigs to an inactivated phase I Coxiella burnetii vaccine" @default.
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- W2135322597 doi "https://doi.org/10.1128/iai.19.1.194-198.1978" @default.
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