FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135324963> ?p ?o ?g. }

• W2135324963 endingPage "565" @default.
• W2135324963 startingPage "555" @default.
• W2135324963 abstract "Chemical exchange saturation transfer (CEST) MRI holds great promise for the imaging of pH. However, routine CEST measurement varies not only with the pH-dependent chemical exchange rate, but also with CEST agent concentration, providing pH-weighted information. Conventional ratiometric CEST imaging normalizes the confounding concentration factor by analyzing the relative CEST effect from different exchangeable groups, requiring CEST agents with multiple chemically distinguishable labile proton sites. Recently, a radiofrequency (RF) power-based ratiometric CEST MRI approach has been developed for concentration-independent pH MRI using CEST agents with a single exchangeable group. To facilitate quantification and optimization of the new ratiometric analysis, we quantified the RF power-based ratiometric CEST ratio (rCESTR) and derived its signal-to-noise and contrast-to-noise ratios. Using creatine as a representative CEST agent containing a single exchangeable site, our study demonstrated that optimized RF power-based ratiometric analysis provides good pH sensitivity. We showed that rCESTR follows a base-catalyzed exchange relationship with pH independent of creatine concentration. The pH accuracy of RF power-based ratiometric MRI was within 0.15–0.20 pH units. Furthermore, the absolute exchange rate can be obtained from the proposed ratiometric analysis. To summarize, RF power-based ratiometric CEST analysis provides concentration-independent pH-sensitive imaging and complements conventional multiple labile proton group-based ratiometric CEST analysis. Copyright © 2015 John Wiley & Sons, Ltd." @default.
• W2135324963 created "2016-06-24" @default.
• W2135324963 creator A5038724542 @default.
• W2135324963 creator A5060043482 @default.
• W2135324963 creator A5087993732 @default.
• W2135324963 creator A5091810273 @default.
• W2135324963 date "2015-03-23" @default.
• W2135324963 modified "2023-09-24" @default.
• W2135324963 title "Quantitative description of radiofrequency (RF) power-based ratiometric chemical exchange saturation transfer (CEST) pH imaging" @default.
• W2135324963 cites W1482675544 @default.
• W2135324963 cites W1484173095 @default.
• W2135324963 cites W1523464062 @default.
• W2135324963 cites W1529856712 @default.
• W2135324963 cites W1564236750 @default.
• W2135324963 cites W1567012656 @default.
• W2135324963 cites W1575499116 @default.
• W2135324963 cites W1742015296 @default.
• W2135324963 cites W1777733060 @default.
• W2135324963 cites W1893000610 @default.
• W2135324963 cites W1913590073 @default.
• W2135324963 cites W1969270500 @default.
• W2135324963 cites W1971077570 @default.
• W2135324963 cites W1985021401 @default.
• W2135324963 cites W1986357760 @default.
• W2135324963 cites W1986720548 @default.
• W2135324963 cites W1989272787 @default.
• W2135324963 cites W1995721991 @default.
• W2135324963 cites W1999936166 @default.
• W2135324963 cites W2003663522 @default.
• W2135324963 cites W2012678826 @default.
• W2135324963 cites W2015570539 @default.
• W2135324963 cites W2024143103 @default.
• W2135324963 cites W2034197771 @default.
• W2135324963 cites W2038423126 @default.
• W2135324963 cites W2039462446 @default.
• W2135324963 cites W2045543202 @default.
• W2135324963 cites W2047653117 @default.
• W2135324963 cites W2052194504 @default.
• W2135324963 cites W2064588148 @default.
• W2135324963 cites W2070231190 @default.
• W2135324963 cites W2072418533 @default.
• W2135324963 cites W2072510712 @default.
• W2135324963 cites W2076766917 @default.
• W2135324963 cites W2081626096 @default.
• W2135324963 cites W2087991725 @default.
• W2135324963 cites W2092996352 @default.
• W2135324963 cites W2093864226 @default.
• W2135324963 cites W2095925829 @default.
• W2135324963 cites W2099520567 @default.
• W2135324963 cites W2109983572 @default.
• W2135324963 cites W2118264574 @default.
• W2135324963 cites W2123554390 @default.
• W2135324963 cites W2125566554 @default.
• W2135324963 cites W2130433813 @default.
• W2135324963 cites W2131489888 @default.
• W2135324963 cites W2132514922 @default.
• W2135324963 cites W2152095654 @default.
• W2135324963 cites W2153548049 @default.
• W2135324963 cites W2156619632 @default.
• W2135324963 cites W2169504259 @default.
• W2135324963 cites W2187309988 @default.
• W2135324963 doi "https://doi.org/10.1002/nbm.3284" @default.
• W2135324963 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4423622" @default.
• W2135324963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25807919" @default.
• W2135324963 hasPublicationYear "2015" @default.
• W2135324963 type Work @default.
• W2135324963 sameAs 2135324963 @default.
• W2135324963 citedByCount "52" @default.
• W2135324963 countsByYear W21353249632015 @default.
• W2135324963 countsByYear W21353249632016 @default.
• W2135324963 countsByYear W21353249632017 @default.
• W2135324963 countsByYear W21353249632018 @default.
• W2135324963 countsByYear W21353249632019 @default.
• W2135324963 countsByYear W21353249632020 @default.
• W2135324963 countsByYear W21353249632021 @default.
• W2135324963 countsByYear W21353249632022 @default.
• W2135324963 countsByYear W21353249632023 @default.
• W2135324963 crossrefType "journal-article" @default.
• W2135324963 hasAuthorship W2135324963A5038724542 @default.
• W2135324963 hasAuthorship W2135324963A5060043482 @default.
• W2135324963 hasAuthorship W2135324963A5087993732 @default.
• W2135324963 hasAuthorship W2135324963A5091810273 @default.
• W2135324963 hasBestOaLocation W21353249632 @default.
• W2135324963 hasConcept C113196181 @default.
• W2135324963 hasConcept C114614502 @default.
• W2135324963 hasConcept C121332964 @default.
• W2135324963 hasConcept C126838900 @default.
• W2135324963 hasConcept C134897140 @default.
• W2135324963 hasConcept C143409427 @default.
• W2135324963 hasConcept C185592680 @default.
• W2135324963 hasConcept C192562407 @default.
• W2135324963 hasConcept C194257627 @default.
• W2135324963 hasConcept C196054291 @default.
• W2135324963 hasConcept C2779896295 @default.
• W2135324963 hasConcept C33923547 @default.
• W2135324963 hasConcept C43617362 @default.
• W2135324963 hasConcept C46141821 @default.
• W2135324963 hasConcept C46362747 @default.

• next