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- W2135406504 abstract "A method is presented which allows the identification and assay of a nucleoside in the presence of other analogues and homologues. The method is based on the conventional multiple reaction monitoring approach performed on the [M + H]+ ions of wild-type and modified nucleosides produced by the turbo ionspray ionization method on a triple-quadrupole mass spectrometer. The accuracy of the quantitative determination relies on the evaluation of a response factor rho, which takes into account the kinetics of dissociation of the parent ions into the protonated [B + 2H]+ nucleobase ions. The evaluation of the absolute concentration of each analyte in the examined mixture does not require any previous chromatographic separation." @default.
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- W2135406504 date "2004-01-01" @default.
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- W2135406504 title "Identification and assay of wild-type and modified nucleoside mixtures by turbo ionspray ionization tandem mass spectrometry" @default.
- W2135406504 doi "https://doi.org/10.1002/jms.553" @default.
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