Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135432022> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2135432022 endingPage "1624" @default.
- W2135432022 startingPage "1613" @default.
- W2135432022 abstract "The cognate sequence of transcription factor PTF1, which plays a key role in pancreas-specific gene expression, has a bipartite organization. Two separate DNA domains, the A and the B boxes, are required for efficient binding of the factor. The structure of PTF1 was elucidated by cross-linking purified PTF1 to DNA templates that had been differentially substituted with azido-deoxyuridine (N3.dU). This site-directed UV cross-linking shows that PTF1 contains two DNA-binding proteins, distinct in size and sensitivity to Staphylococcus aureus V8 protease. A 64-kD protein is cross-linked with DNA containing N3.dU substitutions in the A box, and a 48-kD protein is cross-linked with DNA containing N3.dU substitutions in the B box. Both proteins bind simultaneously to the same DNA molecule. The data indicate that PTF1 is a heteromeric oligomer and that its cell-specific DNA-binding potential is the result of a concerted activity of two DNA-binding subunits." @default.
- W2135432022 created "2016-06-24" @default.
- W2135432022 creator A5004096471 @default.
- W2135432022 creator A5009761125 @default.
- W2135432022 creator A5036860444 @default.
- W2135432022 creator A5059280249 @default.
- W2135432022 date "1989-10-01" @default.
- W2135432022 modified "2023-10-15" @default.
- W2135432022 title "The cell-specific transcription factor PTF1 contains two different subunits that interact with the DNA." @default.
- W2135432022 cites W1976039017 @default.
- W2135432022 cites W1987897953 @default.
- W2135432022 cites W1993243592 @default.
- W2135432022 cites W2009348996 @default.
- W2135432022 cites W2011630904 @default.
- W2135432022 cites W2037753946 @default.
- W2135432022 cites W2048356148 @default.
- W2135432022 cites W2056315045 @default.
- W2135432022 cites W2071525868 @default.
- W2135432022 cites W2076134621 @default.
- W2135432022 cites W2081062649 @default.
- W2135432022 cites W2083141726 @default.
- W2135432022 cites W2100837269 @default.
- W2135432022 cites W55452206 @default.
- W2135432022 doi "https://doi.org/10.1101/gad.3.10.1613" @default.
- W2135432022 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2612907" @default.
- W2135432022 hasPublicationYear "1989" @default.
- W2135432022 type Work @default.
- W2135432022 sameAs 2135432022 @default.
- W2135432022 citedByCount "79" @default.
- W2135432022 countsByYear W21354320222013 @default.
- W2135432022 countsByYear W21354320222014 @default.
- W2135432022 countsByYear W21354320222015 @default.
- W2135432022 countsByYear W21354320222016 @default.
- W2135432022 countsByYear W21354320222017 @default.
- W2135432022 countsByYear W21354320222022 @default.
- W2135432022 crossrefType "journal-article" @default.
- W2135432022 hasAuthorship W2135432022A5004096471 @default.
- W2135432022 hasAuthorship W2135432022A5009761125 @default.
- W2135432022 hasAuthorship W2135432022A5036860444 @default.
- W2135432022 hasAuthorship W2135432022A5059280249 @default.
- W2135432022 hasBestOaLocation W21354320221 @default.
- W2135432022 hasConcept C101762097 @default.
- W2135432022 hasConcept C104317684 @default.
- W2135432022 hasConcept C150194340 @default.
- W2135432022 hasConcept C153911025 @default.
- W2135432022 hasConcept C156719811 @default.
- W2135432022 hasConcept C31254050 @default.
- W2135432022 hasConcept C3662595 @default.
- W2135432022 hasConcept C5179208 @default.
- W2135432022 hasConcept C54355233 @default.
- W2135432022 hasConcept C552990157 @default.
- W2135432022 hasConcept C67705224 @default.
- W2135432022 hasConcept C86339819 @default.
- W2135432022 hasConcept C86803240 @default.
- W2135432022 hasConcept C94966510 @default.
- W2135432022 hasConceptScore W2135432022C101762097 @default.
- W2135432022 hasConceptScore W2135432022C104317684 @default.
- W2135432022 hasConceptScore W2135432022C150194340 @default.
- W2135432022 hasConceptScore W2135432022C153911025 @default.
- W2135432022 hasConceptScore W2135432022C156719811 @default.
- W2135432022 hasConceptScore W2135432022C31254050 @default.
- W2135432022 hasConceptScore W2135432022C3662595 @default.
- W2135432022 hasConceptScore W2135432022C5179208 @default.
- W2135432022 hasConceptScore W2135432022C54355233 @default.
- W2135432022 hasConceptScore W2135432022C552990157 @default.
- W2135432022 hasConceptScore W2135432022C67705224 @default.
- W2135432022 hasConceptScore W2135432022C86339819 @default.
- W2135432022 hasConceptScore W2135432022C86803240 @default.
- W2135432022 hasConceptScore W2135432022C94966510 @default.
- W2135432022 hasIssue "10" @default.
- W2135432022 hasLocation W21354320221 @default.
- W2135432022 hasLocation W21354320222 @default.
- W2135432022 hasOpenAccess W2135432022 @default.
- W2135432022 hasPrimaryLocation W21354320221 @default.
- W2135432022 hasRelatedWork W1776902257 @default.
- W2135432022 hasRelatedWork W1870851597 @default.
- W2135432022 hasRelatedWork W1926921733 @default.
- W2135432022 hasRelatedWork W1974642429 @default.
- W2135432022 hasRelatedWork W2028056900 @default.
- W2135432022 hasRelatedWork W2030922238 @default.
- W2135432022 hasRelatedWork W2052894840 @default.
- W2135432022 hasRelatedWork W2094829359 @default.
- W2135432022 hasRelatedWork W2099901107 @default.
- W2135432022 hasRelatedWork W2148072770 @default.
- W2135432022 hasVolume "3" @default.
- W2135432022 isParatext "false" @default.
- W2135432022 isRetracted "false" @default.
- W2135432022 magId "2135432022" @default.
- W2135432022 workType "article" @default.