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- W2135440014 abstract "Three cases of acute myeloid leukæmia developing after treatment of renal disease with cyclophosphamide have been studied. None of the cases was complicated by additional treatment with irradiation or other cytotoxic agents, or by a pre-existing malignancy. Marrow aplasia as a cause of the leukæmia was ruled out. It is suggested that the immunosuppressive action of cyclophosphamide could predispose to the development of malignancy in two ways: malignant clones of cells could emerge and multiply or oncogenic viruses could invade the cells or escape from immunological control and cause induction and development of malignancy." @default.
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- W2135440014 date "1976-10-01" @default.
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- W2135440014 title "ACUTE LEUKqMIA AFTER IMMUNOSUPPRESSIVE THERAPY" @default.
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- W2135440014 doi "https://doi.org/10.1016/s0140-6736(76)90601-2" @default.
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