FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135480887> ?p ?o ?g. }

• W2135480887 endingPage "811" @default.
• W2135480887 startingPage "803" @default.
• W2135480887 abstract "Abstract Eating disorders (EDs) are common, complex psychiatric disorders thought to be caused by both genetic and environmental factors. They share many symptoms, behaviors, and personality traits, which may have overlapping heritability. The aim of the present study is to perform a genome‐wide association scan (GWAS) of six ED phenotypes comprising three symptom traits from the Eating Disorders Inventory 2 [Drive for Thinness (DT), Body Dissatisfaction (BD), and Bulimia], Weight Fluctuation symptom, Breakfast Skipping behavior and Childhood Obsessive‐Compulsive Personality Disorder trait (CHIRP). Investigated traits were derived from standardized self‐report questionnaires completed by the TwinsUK population‐based cohort. We tested 283,744 directly typed SNPs across six phenotypes of interest in the TwinsUK discovery dataset and followed‐up signals from various strata using a two‐stage replication strategy in two independent cohorts of European ancestry. We meta‐analyzed a total of 2,698 individuals for DT, 2,680 for BD, 2,789 (821 cases/1,968 controls) for Bulimia, 1,360 (633 cases/727 controls) for Childhood Obsessive‐Compulsive Personality Disorder trait, 2,773 (761 cases/2,012 controls) for Breakfast Skipping, and 2,967 (798 cases/2,169 controls) for Weight Fluctuation symptom. In this GWAS analysis of six ED‐related phenotypes, we detected association of eight genetic variants with P < 10 −5 . Genetic variants that showed suggestive evidence of association were previously associated with several psychiatric disorders and ED‐related phenotypes. Our study indicates that larger‐scale collaborative studies will be needed to achieve the necessary power to detect loci underlying ED‐related traits. © 2012 Wiley Periodicals, Inc." @default.
• W2135480887 created "2016-06-24" @default.
• W2135480887 creator A5001189613 @default.
• W2135480887 creator A5002163035 @default.
• W2135480887 creator A5002275174 @default.
• W2135480887 creator A5003288631 @default.
• W2135480887 creator A5007372549 @default.
• W2135480887 creator A5008603870 @default.
• W2135480887 creator A5014265218 @default.
• W2135480887 creator A5022974046 @default.
• W2135480887 creator A5029450538 @default.
• W2135480887 creator A5033960191 @default.
• W2135480887 creator A5034429982 @default.
• W2135480887 creator A5039024549 @default.
• W2135480887 creator A5040292172 @default.
• W2135480887 creator A5040396775 @default.
• W2135480887 creator A5044451947 @default.
• W2135480887 creator A5045227106 @default.
• W2135480887 creator A5069142629 @default.
• W2135480887 creator A5084864301 @default.
• W2135480887 creator A5088314605 @default.
• W2135480887 creator A5091657371 @default.
• W2135480887 date "2012-08-22" @default.
• W2135480887 modified "2023-10-17" @default.
• W2135480887 title "Genome‐wide association analysis of eating disorder‐related symptoms, behaviors, and personality traits" @default.
• W2135480887 cites W1967798359 @default.
• W2135480887 cites W1972336119 @default.
• W2135480887 cites W1977489472 @default.
• W2135480887 cites W1982907532 @default.
• W2135480887 cites W1984623971 @default.
• W2135480887 cites W1993286472 @default.
• W2135480887 cites W1997372554 @default.
• W2135480887 cites W2004001050 @default.
• W2135480887 cites W2014576907 @default.
• W2135480887 cites W2018081447 @default.
• W2135480887 cites W2020954807 @default.
• W2135480887 cites W2029382650 @default.
• W2135480887 cites W2029691985 @default.
• W2135480887 cites W2034464183 @default.
• W2135480887 cites W2041588928 @default.
• W2135480887 cites W2044148171 @default.
• W2135480887 cites W2044245131 @default.
• W2135480887 cites W2048687970 @default.
• W2135480887 cites W2053725906 @default.
• W2135480887 cites W2059900765 @default.
• W2135480887 cites W2063838385 @default.
• W2135480887 cites W2065536425 @default.
• W2135480887 cites W2079602051 @default.
• W2135480887 cites W2081191076 @default.
• W2135480887 cites W2084748751 @default.
• W2135480887 cites W2087683833 @default.
• W2135480887 cites W2094017200 @default.
• W2135480887 cites W2097706816 @default.
• W2135480887 cites W2101413010 @default.
• W2135480887 cites W2102322292 @default.
• W2135480887 cites W2103550195 @default.
• W2135480887 cites W2110846909 @default.
• W2135480887 cites W2115948763 @default.
• W2135480887 cites W2120953128 @default.
• W2135480887 cites W2122592421 @default.
• W2135480887 cites W2128642001 @default.
• W2135480887 cites W2130427506 @default.
• W2135480887 cites W2130856032 @default.
• W2135480887 cites W2134323601 @default.
• W2135480887 cites W2135839670 @default.
• W2135480887 cites W2136558851 @default.
• W2135480887 cites W2140736091 @default.
• W2135480887 cites W2146738944 @default.
• W2135480887 cites W2158911468 @default.
• W2135480887 cites W2161847095 @default.
• W2135480887 cites W2167884000 @default.
• W2135480887 cites W2283508680 @default.
• W2135480887 cites W2414900583 @default.
• W2135480887 cites W4211261481 @default.
• W2135480887 cites W4235405857 @default.
• W2135480887 doi "https://doi.org/10.1002/ajmg.b.32087" @default.
• W2135480887 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3494378" @default.
• W2135480887 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22911880" @default.
• W2135480887 hasPublicationYear "2012" @default.
• W2135480887 type Work @default.
• W2135480887 sameAs 2135480887 @default.
• W2135480887 citedByCount "51" @default.
• W2135480887 countsByYear W21354808872013 @default.
• W2135480887 countsByYear W21354808872014 @default.
• W2135480887 countsByYear W21354808872015 @default.
• W2135480887 countsByYear W21354808872016 @default.
• W2135480887 countsByYear W21354808872017 @default.
• W2135480887 countsByYear W21354808872019 @default.
• W2135480887 countsByYear W21354808872020 @default.
• W2135480887 countsByYear W21354808872021 @default.
• W2135480887 countsByYear W21354808872022 @default.
• W2135480887 countsByYear W21354808872023 @default.
• W2135480887 crossrefType "journal-article" @default.
• W2135480887 hasAuthorship W2135480887A5001189613 @default.
• W2135480887 hasAuthorship W2135480887A5002163035 @default.
• W2135480887 hasAuthorship W2135480887A5002275174 @default.
• W2135480887 hasAuthorship W2135480887A5003288631 @default.
• W2135480887 hasAuthorship W2135480887A5007372549 @default.

• next