FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2135540660> ?p ?o ?g. }

• W2135540660 endingPage "686" @default.
• W2135540660 startingPage "680" @default.
• W2135540660 abstract "Background— Guidelines for anticoagulant therapy in patients with atrial fibrillation are based on stroke risk as calculated by either the CHADS 2 or the CHA 2 DS 2 VASc scores and do not integrate bleeding risk in an explicit, quantitative manner. Our objective was to quantify the net clinical benefit resulting from improved decision making about antithrombotic therapy. Methods and Results— This study is a retrospective cohort study of 1876 adults with nonvalvular atrial fibrillation or flutter seen in primary care settings of an integrated healthcare delivery system between December 2012 and January 2014. Projections for quality-adjusted life expectancy reported as quality-adjusted life-years were calculated by a decision analytic model that integrates patient-specific risk factors for stroke and hemorrhage and examines strategies of no antithrombotic therapy, aspirin, or oral anticoagulation with warfarin. Net clinical benefit was defined by the gain or loss in quality-adjusted life expectancy between current treatment and treatment recommended by an Atrial Fibrillation Decision Support Tool. Current treatment was discordant from treatment recommended by the Atrial Fibrillation Decision Support Tool in 931 patients. A clinically significant gain in quality-adjusted life expectancy (defined as ≥0.1 quality-adjusted life-years) was projected in 832 patients. Subgroups were examined. For example, oral anticoagulant therapy was recommended for 188 who currently were receiving no antithrombotic therapy. For the entire cohort, a total of 736 quality-adjusted life-years could be gained were treatment changed to that recommended by the Atrial Fibrillation Decision Support Tool. Conclusions— Use of a decision support tool that integrates patient-specific stroke and bleeding risk could result in significant gains in quality-adjusted life expectancy for a primary care population of patients with atrial fibrillation." @default.
• W2135540660 created "2016-06-24" @default.
• W2135540660 creator A5000282567 @default.
• W2135540660 creator A5004994895 @default.
• W2135540660 creator A5006246283 @default.
• W2135540660 creator A5015108133 @default.
• W2135540660 creator A5020964569 @default.
• W2135540660 creator A5024175492 @default.
• W2135540660 creator A5024653715 @default.
• W2135540660 creator A5024671507 @default.
• W2135540660 creator A5038405190 @default.
• W2135540660 creator A5040020177 @default.
• W2135540660 creator A5040268432 @default.
• W2135540660 creator A5050794885 @default.
• W2135540660 creator A5053897572 @default.
• W2135540660 creator A5056458209 @default.
• W2135540660 creator A5067359683 @default.
• W2135540660 creator A5071022843 @default.
• W2135540660 creator A5083506995 @default.
• W2135540660 creator A5086132499 @default.
• W2135540660 creator A5086193367 @default.
• W2135540660 creator A5091740246 @default.
• W2135540660 date "2014-09-01" @default.
• W2135540660 modified "2023-09-23" @default.
• W2135540660 title "Integrating Real-Time Clinical Information to Provide Estimates of Net Clinical Benefit of Antithrombotic Therapy for Patients With Atrial Fibrillation" @default.
• W2135540660 cites W127340632 @default.
• W2135540660 cites W1586488555 @default.
• W2135540660 cites W1964685156 @default.
• W2135540660 cites W1967046500 @default.
• W2135540660 cites W1972218629 @default.
• W2135540660 cites W2000372136 @default.
• W2135540660 cites W2011936209 @default.
• W2135540660 cites W2039531178 @default.
• W2135540660 cites W2057748188 @default.
• W2135540660 cites W2066157763 @default.
• W2135540660 cites W2067443499 @default.
• W2135540660 cites W2077250899 @default.
• W2135540660 cites W2094969018 @default.
• W2135540660 cites W2119221555 @default.
• W2135540660 cites W2124601103 @default.
• W2135540660 cites W2126206943 @default.
• W2135540660 cites W2127985968 @default.
• W2135540660 cites W2132505348 @default.
• W2135540660 cites W2144891869 @default.
• W2135540660 cites W2152647843 @default.
• W2135540660 cites W2163492706 @default.
• W2135540660 cites W2165762371 @default.
• W2135540660 cites W2337831406 @default.
• W2135540660 cites W2546446487 @default.
• W2135540660 cites W3030533492 @default.
• W2135540660 cites W4252527014 @default.
• W2135540660 doi "https://doi.org/10.1161/circoutcomes.114.001163" @default.
• W2135540660 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25205788" @default.
• W2135540660 hasPublicationYear "2014" @default.
• W2135540660 type Work @default.
• W2135540660 sameAs 2135540660 @default.
• W2135540660 citedByCount "26" @default.
• W2135540660 countsByYear W21355406602015 @default.
• W2135540660 countsByYear W21355406602016 @default.
• W2135540660 countsByYear W21355406602017 @default.
• W2135540660 countsByYear W21355406602018 @default.
• W2135540660 countsByYear W21355406602019 @default.
• W2135540660 countsByYear W21355406602020 @default.
• W2135540660 countsByYear W21355406602022 @default.
• W2135540660 countsByYear W21355406602023 @default.
• W2135540660 crossrefType "journal-article" @default.
• W2135540660 hasAuthorship W2135540660A5000282567 @default.
• W2135540660 hasAuthorship W2135540660A5004994895 @default.
• W2135540660 hasAuthorship W2135540660A5006246283 @default.
• W2135540660 hasAuthorship W2135540660A5015108133 @default.
• W2135540660 hasAuthorship W2135540660A5020964569 @default.
• W2135540660 hasAuthorship W2135540660A5024175492 @default.
• W2135540660 hasAuthorship W2135540660A5024653715 @default.
• W2135540660 hasAuthorship W2135540660A5024671507 @default.
• W2135540660 hasAuthorship W2135540660A5038405190 @default.
• W2135540660 hasAuthorship W2135540660A5040020177 @default.
• W2135540660 hasAuthorship W2135540660A5040268432 @default.
• W2135540660 hasAuthorship W2135540660A5050794885 @default.
• W2135540660 hasAuthorship W2135540660A5053897572 @default.
• W2135540660 hasAuthorship W2135540660A5056458209 @default.
• W2135540660 hasAuthorship W2135540660A5067359683 @default.
• W2135540660 hasAuthorship W2135540660A5071022843 @default.
• W2135540660 hasAuthorship W2135540660A5083506995 @default.
• W2135540660 hasAuthorship W2135540660A5086132499 @default.
• W2135540660 hasAuthorship W2135540660A5086193367 @default.
• W2135540660 hasAuthorship W2135540660A5091740246 @default.
• W2135540660 hasBestOaLocation W21355406601 @default.
• W2135540660 hasConcept C107327155 @default.
• W2135540660 hasConcept C126322002 @default.
• W2135540660 hasConcept C127413603 @default.
• W2135540660 hasConcept C133925201 @default.
• W2135540660 hasConcept C154945302 @default.
• W2135540660 hasConcept C159110408 @default.
• W2135540660 hasConcept C177713679 @default.
• W2135540660 hasConcept C1862650 @default.
• W2135540660 hasConcept C2776301958 @default.
• W2135540660 hasConcept C2777015399 @default.
• W2135540660 hasConcept C2777628954 @default.

• next