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• W2135546946 endingPage "950" @default.
• W2135546946 startingPage "921" @default.
• W2135546946 abstract "This review applies some new experimental findings and theoretical ideas about how reinforcers act on the neural mechanisms of learning and memory to the problem of how addictive drugs affect behaviour. A basic assumption of this analysis is that all changes in behaviour, including those involved in drug addiction and the initiation of drug self-administration, require the storage of new information in the nervous system. Animal studies suggest that such information is processed in several (this review deals with three) more or less independent learning and memory systems in the mammalian brain. Reinforcers can interact with these systems in three ways: they activate neural substrates of observable approach or escape responses, they produce unobservable internal states that can be perceived as rewarding or aversive, and they modulate or enhance the information stored in each of the memory systems. It is suggested that each addictive drug maintains its own self-administration by mimicking some subset of these actions. Evidence supporting the notion of multiple memory systems and data on the actions of several drugs (amphetamine, cocaine, nicotine, alcohol and morphine) on these systems are briefly reviewed. The utility of the concept of “reward” for understanding the effects of drugs on behaviour is discussed. Evidence demonstrating actions of drugs on multiple neural substrates of reinforcement suggests that no single factor is likely to explain either addictive behaviour in general or self-administration in particular. Some of the findings on the development and maintenance of self-administration by animals of the five exemplar drugs are discussed in the context of these ideas." @default.
• W2135546946 created "2016-06-24" @default.
• W2135546946 creator A5081348091 @default.
• W2135546946 date "1996-07-01" @default.
• W2135546946 modified "2023-10-10" @default.
• W2135546946 title "Addictive drugs as reinforcers: multiple partial actions on memory systems" @default.
• W2135546946 cites W113523507 @default.
• W2135546946 cites W1163570360 @default.
• W2135546946 cites W1526520529 @default.
• W2135546946 cites W1576139686 @default.
• W2135546946 cites W1588642945 @default.
• W2135546946 cites W163271895 @default.
• W2135546946 cites W164622610 @default.
• W2135546946 cites W1912922016 @default.
• W2135546946 cites W1963482390 @default.
• W2135546946 cites W1963894555 @default.
• W2135546946 cites W1964115906 @default.
• W2135546946 cites W1964388466 @default.
• W2135546946 cites W1964394862 @default.
• W2135546946 cites W1964890792 @default.
• W2135546946 cites W1964909230 @default.
• W2135546946 cites W1965676891 @default.
• W2135546946 cites W1966778920 @default.
• W2135546946 cites W1967236505 @default.
• W2135546946 cites W1968404715 @default.
• W2135546946 cites W1969247127 @default.
• W2135546946 cites W1970514326 @default.
• W2135546946 cites W1972396583 @default.
• W2135546946 cites W1973529564 @default.
• W2135546946 cites W1974100637 @default.
• W2135546946 cites W1974330214 @default.
• W2135546946 cites W1974692779 @default.
• W2135546946 cites W1975704730 @default.
• W2135546946 cites W1975782714 @default.
• W2135546946 cites W1976213197 @default.
• W2135546946 cites W1976454573 @default.
• W2135546946 cites W1976754102 @default.
• W2135546946 cites W1979293058 @default.
• W2135546946 cites W1979684634 @default.
• W2135546946 cites W1979907350 @default.
• W2135546946 cites W1982641194 @default.
• W2135546946 cites W1982869197 @default.
• W2135546946 cites W1982956447 @default.
• W2135546946 cites W1984039810 @default.
• W2135546946 cites W1984110918 @default.
• W2135546946 cites W1984572605 @default.
• W2135546946 cites W1985647135 @default.
• W2135546946 cites W1988234143 @default.
• W2135546946 cites W1988733693 @default.
• W2135546946 cites W1988749016 @default.
• W2135546946 cites W1989895849 @default.
• W2135546946 cites W1989905120 @default.
• W2135546946 cites W1990407463 @default.
• W2135546946 cites W1990599317 @default.
• W2135546946 cites W1991169887 @default.
• W2135546946 cites W1991789082 @default.
• W2135546946 cites W1991857869 @default.
• W2135546946 cites W1993202660 @default.
• W2135546946 cites W1994237258 @default.
• W2135546946 cites W1994744737 @default.
• W2135546946 cites W1995866585 @default.
• W2135546946 cites W1997216215 @default.
• W2135546946 cites W1998459031 @default.
• W2135546946 cites W1998483562 @default.
• W2135546946 cites W1998501022 @default.
• W2135546946 cites W1999131869 @default.
• W2135546946 cites W1999286995 @default.
• W2135546946 cites W1999464270 @default.
• W2135546946 cites W1999727386 @default.
• W2135546946 cites W1999813581 @default.
• W2135546946 cites W1999971120 @default.
• W2135546946 cites W2000667455 @default.
• W2135546946 cites W2001865657 @default.
• W2135546946 cites W2002140212 @default.
• W2135546946 cites W2002953387 @default.
• W2135546946 cites W2003290371 @default.
• W2135546946 cites W2004195455 @default.
• W2135546946 cites W2004676408 @default.
• W2135546946 cites W2005236279 @default.
• W2135546946 cites W2005657014 @default.
• W2135546946 cites W2005997674 @default.
• W2135546946 cites W2006256936 @default.
• W2135546946 cites W2006990598 @default.
• W2135546946 cites W2007169577 @default.
• W2135546946 cites W2007455229 @default.
• W2135546946 cites W2007942266 @default.
• W2135546946 cites W2009778458 @default.
• W2135546946 cites W2010095814 @default.
• W2135546946 cites W2010169238 @default.
• W2135546946 cites W2010569958 @default.
• W2135546946 cites W2010671209 @default.
• W2135546946 cites W2011063805 @default.
• W2135546946 cites W2011154525 @default.
• W2135546946 cites W2011178927 @default.
• W2135546946 cites W2011246896 @default.
• W2135546946 cites W2012512063 @default.
• W2135546946 cites W2012587996 @default.
• W2135546946 cites W2012747866 @default.

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