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- W2135563623 endingPage "379" @default.
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- W2135563623 abstract "SUMMARY Infection of humans with the nematode worm parasite Anisakis simplex was first described in the 1960s in association with the consumption of raw or undercooked fish. During the 1990s it was realized that even the ingestion of dead worms in food fish can cause severe hypersensitivity reactions, that these may be more prevalent than infection itself, and that this outcome could be associated with food preparations previously considered safe. Not only may allergic symptoms arise from infection by the parasites (“gastroallergic anisakiasis”), but true anaphylactic reactions can also occur following exposure to allergens from dead worms by food-borne, airborne, or skin contact routes. This review discusses A. simplex pathogenesis in humans, covering immune hypersensitivity reactions both in the context of a living infection and in terms of exposure to its allergens by other routes. Over the last 20 years, several studies have concentrated on A. simplex antigen characterization and innate as well as adaptive immune response to this parasite. Molecular characterization of Anisakis allergens and isolation of their encoding cDNAs is now an active field of research that should provide improved diagnostic tools in addition to tools with which to enhance our understanding of pathogenesis and controversial aspects of A. simplex allergy. We also discuss the potential relevance of parasite products such as allergens, proteinases, and proteinase inhibitors and the activation of basophils, eosinophils, and mast cells in the induction of A. simplex -related immune hypersensitivity states induced by exposure to the parasite, dead or alive." @default.
- W2135563623 created "2016-06-24" @default.
- W2135563623 creator A5021580384 @default.
- W2135563623 creator A5045555799 @default.
- W2135563623 date "2008-04-01" @default.
- W2135563623 modified "2023-10-02" @default.
- W2135563623 title "<i>Anisakis simplex</i> : from Obscure Infectious Worm to Inducer of Immune Hypersensitivity" @default.
- W2135563623 cites W1485077063 @default.
- W2135563623 cites W1508294714 @default.
- W2135563623 cites W1513699960 @default.
- W2135563623 cites W1518189780 @default.
- W2135563623 cites W1526031328 @default.
- W2135563623 cites W1602406214 @default.
- W2135563623 cites W1603126127 @default.
- W2135563623 cites W1785508065 @default.
- W2135563623 cites W1900981725 @default.
- W2135563623 cites W1929340328 @default.
- W2135563623 cites W194956367 @default.
- W2135563623 cites W1963907257 @default.
- W2135563623 cites W1964551771 @default.
- W2135563623 cites W1966426214 @default.
- W2135563623 cites W1968961392 @default.
- W2135563623 cites W1970667784 @default.
- W2135563623 cites W1971191023 @default.
- W2135563623 cites W1973140142 @default.
- W2135563623 cites W1973723753 @default.
- W2135563623 cites W1973776145 @default.
- W2135563623 cites W1974345115 @default.
- W2135563623 cites W1974415615 @default.
- W2135563623 cites W1975190212 @default.
- W2135563623 cites W1975449550 @default.
- W2135563623 cites W1975800949 @default.
- W2135563623 cites W1978013324 @default.
- W2135563623 cites W1979365546 @default.
- W2135563623 cites W1979419170 @default.
- W2135563623 cites W1979757635 @default.
- W2135563623 cites W1980049685 @default.
- W2135563623 cites W1982293312 @default.
- W2135563623 cites W1986959599 @default.
- W2135563623 cites W1987999181 @default.
- W2135563623 cites W1988884354 @default.
- W2135563623 cites W1989151135 @default.
- W2135563623 cites W1990306286 @default.
- W2135563623 cites W1990409100 @default.
- W2135563623 cites W1992345614 @default.
- W2135563623 cites W1992613748 @default.
- W2135563623 cites W1993548203 @default.
- W2135563623 cites W1993829167 @default.
- W2135563623 cites W1994209044 @default.
- W2135563623 cites W1994853634 @default.
- W2135563623 cites W1996404346 @default.
- W2135563623 cites W1997048122 @default.
- W2135563623 cites W1997196506 @default.
- W2135563623 cites W1997453211 @default.
- W2135563623 cites W2001219252 @default.
- W2135563623 cites W2001607819 @default.
- W2135563623 cites W2001757816 @default.
- W2135563623 cites W2002126735 @default.
- W2135563623 cites W2002935863 @default.
- W2135563623 cites W2004619863 @default.
- W2135563623 cites W2005231879 @default.
- W2135563623 cites W2005553694 @default.
- W2135563623 cites W2005973133 @default.
- W2135563623 cites W2007683482 @default.
- W2135563623 cites W2009252429 @default.
- W2135563623 cites W2009972285 @default.
- W2135563623 cites W2010584345 @default.
- W2135563623 cites W2011140256 @default.
- W2135563623 cites W2011467591 @default.
- W2135563623 cites W2011719110 @default.
- W2135563623 cites W2015282703 @default.
- W2135563623 cites W2015694276 @default.
- W2135563623 cites W2016187294 @default.
- W2135563623 cites W2016192098 @default.
- W2135563623 cites W2016679659 @default.
- W2135563623 cites W2019610054 @default.
- W2135563623 cites W2021263576 @default.
- W2135563623 cites W2022017784 @default.
- W2135563623 cites W2023807550 @default.
- W2135563623 cites W2024659034 @default.
- W2135563623 cites W2025074228 @default.
- W2135563623 cites W2026615894 @default.
- W2135563623 cites W2027302925 @default.
- W2135563623 cites W2027725877 @default.
- W2135563623 cites W2028890113 @default.
- W2135563623 cites W2029457676 @default.
- W2135563623 cites W2031501484 @default.
- W2135563623 cites W2031814997 @default.
- W2135563623 cites W2032317828 @default.
- W2135563623 cites W2032336491 @default.
- W2135563623 cites W2032917683 @default.
- W2135563623 cites W2034685358 @default.
- W2135563623 cites W2036597349 @default.
- W2135563623 cites W2037164650 @default.
- W2135563623 cites W2037408454 @default.
- W2135563623 cites W2037462223 @default.
- W2135563623 cites W2037823749 @default.
- W2135563623 cites W2038209432 @default.